在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MATK Antibody

  • 中文名稱:
    MATK兔多克隆抗體
  • 貨號:
    CSB-PA220699
  • 規格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from Jurkat cells, using MATK antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MATK Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from Internal of Human MATK.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
  • 基因功能參考文獻:
    1. After IGF-I stimulation, CTK is recruited to IGF-IR and its recruitment facilitates CTK's subsequent association with phospho-SHPS-1. PMID: 21799000
    2. ERBB2 binds to the SH2 domain of CHK and inhibits cell growth in human breast tumor cell lines PMID: 12122014
    3. Overexpression of the Csk homologous kinase facilitates phosphorylation of akt/protein kinase b in breast neoplasms PMID: 12429987
    4. CHK Leu223 stabilizes the movement of the alphaC-helix of the protein tyrosine kinase PMID: 12782282
    5. Loss of CHK expression is associated with human brain tumors PMID: 15329911
    6. Nuclear multi-lobulation in late S phase, which is dependent on polymerization and depolymerization of microtubules, may be involved in nuclear Chk-induced inhibition of proliferation. PMID: 15748901
    7. striking functional differences between the Csk and Chk SH2 domains and revealed functional similarities between the Chk and Src SH2 domains PMID: 15890649
    8. This study describes for the first time the Src-independent actions of CHK and provides novel insights into CHK function in neural cells. PMID: 16168623
    9. Matk/CHK is not functionally redundant with Csk, and this tyrosine kinase plays an important role as a regulator of immunologic responses PMID: 16574955
    10. Findings indicate that the importance of the N-terminal domain to Chk-induced tyrosine phosphorylation in the nucleus, and implicate that nuclear tyrosine-phosphorylated proteins may contribute to inhibition of cell proliferation. PMID: 16707123
    11. Progesterone increases MATK in mast cells and reducs cell proliferation. PMID: 17492661
    12. These results reveal a potentially important role for CHK in Src activation and tumorigenicity in colon cancer cells. PMID: 17934522
    13. CHK is capable of inhibiting the CXCL12-CXCR4 pathway in neuroblastoma. PMID: 18292939

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Membrane. Note=In platelets, 90% of MATK localizes to the membrane fraction, and translocates to the cytoskeleton upon thrombin stimulation.
  • 蛋白家族:
    Protein kinase superfamily, Tyr protein kinase family, CSK subfamily
  • 組織特異性:
    Expressed in various myeloid cell lines, detected in brain and lung.
  • 數據庫鏈接:

    HGNC: 6906

    OMIM: 600038

    KEGG: hsa:4145

    STRING: 9606.ENSP00000378485

    UniGene: Hs.631845



主站蜘蛛池模板: 人妻丰满熟妇ⅴ无码区a片| 中国精品无码免费专区午夜 | 人人妻人人澡人人爽国产一区| 精品久久一区二区乱码| 中国熟妇内谢69xxxxx| 亚洲男同gv在线观看| 亚洲精品成人片在线播放| 成人午夜无码专区性视频性视频| 18禁裸男晨勃露j毛网站| 少妇高潮太爽了在线视频| 18禁黄污吃奶免费看网站| av无码中文一区二区三区四区| 日本丰满护士爆乳xxxx| 无码视频在线观看| 国产在线精品一区二区不卡麻豆| 国产精品亚洲精品日韩已满十八小| 国产日韩欧美亚欧在线观看| 中文字幕人妻互换av久久| 欧美精品国产aⅴ一区二区在线| 亚洲精品夜夜夜妓女网| 亚洲高清一区二区三区不卡 | 久久日本片精品aaaaa国产| 久久婷婷五月国产色综合| 久久精品国产精品亚洲下载| 亚洲欧美v国产一区二区| 亚洲xxxx做受欧美| 国产一区二区三区成人欧美日韩在线观看 | 色一情一乱一伦一区二区三区| 中文字幕人妻av一区二区| 日韩v亚洲v欧美v精品综合| 免费久久99精品国产自在现线| 亚洲人av在线无码影院观看| 人人爽久久涩噜噜噜av| 视频久re精品在线观看| 欧美疯狂做受xxxx高潮| 精品无码av不卡一区二区三区| 狠狠色狠狠色狠狠五月| 亚洲国产精品一区二区美利坚| 一本色道无码道dvd在线观看| 亚洲人成无码网站18禁10| 国产深夜男女无套内射|