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LSR Antibody, Biotin conjugated

  • 中文名稱:
    LSR兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA801252LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) LSR Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    ILDR3 antibody; Immunoglobulin like domain containing receptor 3 antibody; Lipolysis Stimulated Lipoprotein Receptor antibody; Lipolysis stimulated remnant antibody; Lipolysis-stimulated lipoprotein receptor antibody; LISCH antibody; LISCH protein antibody; LISCH7 antibody; Liver specific bHLH Zip transcription factor antibody; LSR antibody; LSR_HUMAN antibody; MGC10659 antibody; MGC48312 antibody; MGC48503 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Lipolysis-stimulated lipoprotein receptor protein (112-233AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells.
  • 基因功能參考文獻:
    1. this study shows that loss of tricellular tight junction protein LSR promotes cell invasion and migration via upregulation of TEAD1/AREG in endometrial cancer PMID: 28071680
    2. Lipolysis-stimulated lipoprotein receptor (LSR)-deficient CaCo-2 cells exhibited increased cell proliferation. PMID: 27391068
    3. Results of this study provide novel evidence that tricellular tight junctions protein LSR negatively regulates cancer cell progression and development in endometrial cancer. PMID: 27036040
    4. Lipolysis-stimulated lipoprotein receptors (LSRs) localized to bicellular junctions in association with myosin regulatory light chain 2 (MRLC2) at low cell densities and to tricellular contacts when myosin phosphatase target subunit 1 (MYPT1) localized to the bicellular regions. PMID: 28493278
    5. analysis of how Clostridium difficile binary toxin CDT interacts with its host cell receptor, Lipolysis-stimulated Lipoprotein Receptor PMID: 25882847
    6. These data show that Clostridium difficile binary toxin CDT induces clustering of the lipolysis-stimulated lipoprotein receptor into lipid rafts. PMID: 23631918
    7. findings show that Clostridium spiroforme toxin (CST)enters target cells via the lipolysis-stimulated lipoprotein receptor; findings indicate that CST shares LSR with C. difficile CDT and C. perfringens iota toxin as a host cell surface receptor PMID: 22252869
    8. LSR defines tricellular contacts in epithelial cellular sheets by acting as a landmark to recruit tricellulin for tricellular tight junction formation. PMID: 21245199
    9. LISCH7 may have a role in progression of human colon cancer PMID: 17975147

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  • 亞細胞定位:
    Cell membrane; Single-pass membrane protein.
  • 蛋白家族:
    Immunoglobulin superfamily, LISCH7 family
  • 數據庫鏈接:

    HGNC: 29572

    OMIM: 616582

    KEGG: hsa:51599

    STRING: 9606.ENSP00000354575

    UniGene: Hs.466507



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