在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

LRPAP1 Antibody

  • 中文名稱:
    LRPAP1兔多克隆抗體
  • 貨號:
    CSB-PA156966
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA156966(LRPAP1 Antibody) at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: 293T cells, Human fetal kidney tissue, Primary antibody: CSB-PA156966(LRPAP1 Antibody) at dilution 1/1600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    39 kDa receptor-associated protein antibody; A2MRAP antibody; A2RAP antibody; Alpha 2 macroglobulin receptor associated protein antibody; Alpha 2 MRAP antibody; Alpha-2-macroglobulin receptor-associated protein antibody; Alpha-2-MRAP antibody; AMRP_HUMAN antibody; HBP44 antibody; Lipoprotein receptor associated protein antibody; Low density lipoprotein receptor related protein associated protein 1 antibody; Low density lipoprotein receptor-related protein-associated protein 1 antibody; Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein antibody; Low density lipoprotein related protein associated protein 1 antibody; low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1) antibody; Lrpap1 antibody; MGC138272 antibody; MRAP antibody; MYP23 antibody; RAP antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthetic peptide of Human LRPAP1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    WB 1:500-1:2000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.
  • 基因功能參考文獻:
    1. The clinical and biometric features we describe in this report characterize LRPAP1-related high myopia and should raise suspicion for mutations in the gene. PMID: 26271838
    2. The inhibition caused by reagents that prevented the activation of Rap was reversed by mobilizing intracellular calcium pharmacologically, whereas that caused by acrosome reaction inhibitors that impeded Rab3's binding to GTP was not. PMID: 25159528
    3. The LRPAP1 I allelic variant may be considered a candidate gene for PD, predominantly in patients having the APOE epsilon4 allelic variant. PMID: 24504617
    4. RAP inhibited light chain (LC)endocytosis by approximately 88% and ameliorated LC-induced cytokine responses and epithelial-to-mesenchymal transformation in human proximal tubular cells. PMID: 23894629
    5. Mutations in LRPAP1 are associated with severe myopia in humans. PMID: 23830514
    6. LRP1-C/T, A2M-Ile/Val and APOE-epsilon 2/epsilon 3/epsilon 4 polymorphisms are associated with AD. PMID: 20637261
    7. Findings reveal that RAP is a novel Abeta-binding protein that promotes cellular internalization of Abeta. PMID: 19826010
    8. Adenoviral-mediated expression of human receptor-asociated protein RAP in a murine model of von Willebrand disease results in a continuous rise in FVIII over 6 days. PMID: 11992244
    9. RAP is organized into three domains located in the first third (1D), middle third (2D), and last third (3D) of the protein; all three domains adopt stable tertiary structure as isolated domains and are monomers. PMID: 14674767
    10. NMR structure of domain 1 of receptor-associated protein PMID: 15213425
    11. An insertion allele is found to be associated with gallstone disease. PMID: 16704534
    12. RAP is expressed by thyrocytes in a TSH-dependent manner, both in cultured thyroid cells and in vivo PMID: 17123336
    13. analysis of the relationship between ACE and LRPAP1 gene polymorphisms and age in an Italian population PMID: 17536759
    14. Low-density lipoprotein receptor-related protein-associated protein (LRPAP1) gene IVS5 insertion/deletion polymorphism is not a risk factor for gallstone disease in a Polish population. PMID: 17913606
    15. Low-density lipoprotein receptor-related protein associated protein (LRPAP1) insertion/deletion polymorphism is associated with gallstone disease and gallbladder carcinoma PMID: 17987404
    16. LRP-1/LDLR-mediated uptake of A beta results in degeneration of perivascular cells. PMID: 18055545
    17. alterations of the RAP gene are not a common cause of hypothyroidism PMID: 18075286
    18. Our study suggests that LRPAP1-D and APOE E4 alleles significantly increase the susceptibility to degenerative dementias. PMID: 18721259

    顯示更多

    收起更多

  • 相關疾病:
    Myopia 23, autosomal recessive (MYP23)
  • 亞細胞定位:
    Rough endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment lumen. Golgi apparatus, cis-Golgi network. Golgi apparatus lumen. Endosome lumen. Cell surface.
  • 蛋白家族:
    Alpha-2-MRAP family
  • 數據庫鏈接:

    HGNC: 6701

    OMIM: 104225

    KEGG: hsa:4043

    STRING: 9606.ENSP00000421922

    UniGene: Hs.40966



主站蜘蛛池模板: 亚洲精品成a人在线观看| 国产精品无码久久av不卡| 青娱国产区在线| 少妇被多人c夜夜爽爽| 抽插丰满内射高潮视频| 国产乱了真实在线观看| 美女粉嫩饱满的一线天mp4| 无码一区二区三区av在线播放| 四虎成人精品永久在线视频 | 国产激情精品一区二区三区| 久久99国产只有精品| 久久毛片免费看一区二区三区 | 怡红院一区二区三区在线| 日本免费大黄在线观看| 无码人妻一区二区三区免费视频| 女乱高潮久久久久久爽爽| 日韩人妻无码精品二专区| 日本韩国亚洲欧美在线 | 国产精品美女久久久久久2018| 亚洲欧美精品suv| 2021国产精品香蕉在线观看 | 宝贝腿开大点我添添公视频免费| 成av人片一区二区三区久久 | 色婷婷久久久swag精品| 在教室伦流澡到高潮hgl动漫| 中文字幕一区二区三区久久网站 | 熟妇人妻中文字幕无码老熟妇 | 久久亚洲精品无码va白人极品| 免费的黄网站在线观看| 日韩理论午夜无码| 国产亚洲日本精品无码| 亚洲毛片αv无线播放一区| 亚洲精品久久久蜜桃| 精品一卡二卡三卡四卡网站| 亚洲а∨天堂男人色无码| 2019nv天堂香蕉在线观看| 无套熟女av呻吟在线观看| 国内精品久久久久久久电影视| 中文字幕亚洲综合久久菠萝蜜| 日韩精品一区二区三区免费视频| 久久久久人妻一区二区三区vr|