在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

LRPAP1 Antibody, FITC conjugated

  • 中文名稱:
    LRPAP1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA013104HC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) LRPAP1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    39 kDa receptor-associated protein antibody; A2MRAP antibody; A2RAP antibody; Alpha 2 macroglobulin receptor associated protein antibody; Alpha 2 MRAP antibody; Alpha-2-macroglobulin receptor-associated protein antibody; Alpha-2-MRAP antibody; AMRP_HUMAN antibody; HBP44 antibody; Lipoprotein receptor associated protein antibody; Low density lipoprotein receptor related protein associated protein 1 antibody; Low density lipoprotein receptor-related protein-associated protein 1 antibody; Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein antibody; Low density lipoprotein related protein associated protein 1 antibody; low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1) antibody; Lrpap1 antibody; MGC138272 antibody; MRAP antibody; MYP23 antibody; RAP antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Alpha-2-macroglobulin receptor-associated protein (35-357AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.
  • 基因功能參考文獻:
    1. The clinical and biometric features we describe in this report characterize LRPAP1-related high myopia and should raise suspicion for mutations in the gene. PMID: 26271838
    2. The inhibition caused by reagents that prevented the activation of Rap was reversed by mobilizing intracellular calcium pharmacologically, whereas that caused by acrosome reaction inhibitors that impeded Rab3's binding to GTP was not. PMID: 25159528
    3. The LRPAP1 I allelic variant may be considered a candidate gene for PD, predominantly in patients having the APOE epsilon4 allelic variant. PMID: 24504617
    4. RAP inhibited light chain (LC)endocytosis by approximately 88% and ameliorated LC-induced cytokine responses and epithelial-to-mesenchymal transformation in human proximal tubular cells. PMID: 23894629
    5. Mutations in LRPAP1 are associated with severe myopia in humans. PMID: 23830514
    6. LRP1-C/T, A2M-Ile/Val and APOE-epsilon 2/epsilon 3/epsilon 4 polymorphisms are associated with AD. PMID: 20637261
    7. Findings reveal that RAP is a novel Abeta-binding protein that promotes cellular internalization of Abeta. PMID: 19826010
    8. Adenoviral-mediated expression of human receptor-asociated protein RAP in a murine model of von Willebrand disease results in a continuous rise in FVIII over 6 days. PMID: 11992244
    9. RAP is organized into three domains located in the first third (1D), middle third (2D), and last third (3D) of the protein; all three domains adopt stable tertiary structure as isolated domains and are monomers. PMID: 14674767
    10. NMR structure of domain 1 of receptor-associated protein PMID: 15213425
    11. An insertion allele is found to be associated with gallstone disease. PMID: 16704534
    12. RAP is expressed by thyrocytes in a TSH-dependent manner, both in cultured thyroid cells and in vivo PMID: 17123336
    13. analysis of the relationship between ACE and LRPAP1 gene polymorphisms and age in an Italian population PMID: 17536759
    14. Low-density lipoprotein receptor-related protein-associated protein (LRPAP1) gene IVS5 insertion/deletion polymorphism is not a risk factor for gallstone disease in a Polish population. PMID: 17913606
    15. Low-density lipoprotein receptor-related protein associated protein (LRPAP1) insertion/deletion polymorphism is associated with gallstone disease and gallbladder carcinoma PMID: 17987404
    16. LRP-1/LDLR-mediated uptake of A beta results in degeneration of perivascular cells. PMID: 18055545
    17. alterations of the RAP gene are not a common cause of hypothyroidism PMID: 18075286
    18. Our study suggests that LRPAP1-D and APOE E4 alleles significantly increase the susceptibility to degenerative dementias. PMID: 18721259

    顯示更多

    收起更多

  • 相關疾病:
    Myopia 23, autosomal recessive (MYP23)
  • 亞細胞定位:
    Rough endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment lumen. Golgi apparatus, cis-Golgi network. Golgi apparatus lumen. Endosome lumen. Cell surface.
  • 蛋白家族:
    Alpha-2-MRAP family
  • 數據庫鏈接:

    HGNC: 6701

    OMIM: 104225

    KEGG: hsa:4043

    STRING: 9606.ENSP00000421922

    UniGene: Hs.40966



主站蜘蛛池模板: 999成人精品视频在线| 小13箩利洗澡无码视频网站| 又硬又粗进去好爽免费| 在线黑人抽搐潮喷| 狠狠躁18三区二区一区| 国产成人久久精品77777综合| 亚洲精品久久7777777| 性无码专区无码片| 蜜臀色欲av在线播放国产日韩| 蜜臀久久99精品久久久久久小说 | 精品久久久久久久久久中文字幕| 午夜片神马影院福利| 人人爽久久涩噜噜噜av| 久久99国产精品二区| 国产精品综合av一区二区国产馆| 四虎成人精品在永久免费| 美女黄18以下禁止观看| 夜夜爽狠狠天天婷婷五月| 国产精品va尤物在线观看| 国产好大好硬好爽免费视频| 国产无人区码一码二码三mba| 精品人妻一区二区三区浪潮在线| 亚洲日韩av无码一区二区三区| 青青草国产精品一区二区| 亚洲欧美日韩国产另类电影| 嘿咻嘿咻男女免费专区| 中文字幕精品亚洲无线码一区| 老太脱裤子让老头玩xxxxx| 久久精品国产亚洲欧美| 国产欧美日韩精品专区| 免费人成在线观看网站| 日韩人妻熟女中文字幕a美景之屋| 国产精品白浆在线观看免费 | 丰满人妻无奈张开双腿av| 48沈阳熟女高潮嗷嗷叫| 少妇扒开粉嫩小泬视频| 双腿张开被9个黑人调教影片 | 久久无码高潮喷水抽搐| 国产熟睡乱子伦午夜视频麻豆| 成人永久免费网站在线观看| 免费无码a片一区二三区|