在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

LRPAP1 Antibody, Biotin conjugated

  • 中文名稱(chēng):
    LRPAP1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào):
    CSB-PA013104HD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng):
    Rabbit anti-Homo sapiens (Human) LRPAP1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    39 kDa receptor-associated protein antibody; A2MRAP antibody; A2RAP antibody; Alpha 2 macroglobulin receptor associated protein antibody; Alpha 2 MRAP antibody; Alpha-2-macroglobulin receptor-associated protein antibody; Alpha-2-MRAP antibody; AMRP_HUMAN antibody; HBP44 antibody; Lipoprotein receptor associated protein antibody; Low density lipoprotein receptor related protein associated protein 1 antibody; Low density lipoprotein receptor-related protein-associated protein 1 antibody; Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein antibody; Low density lipoprotein related protein associated protein 1 antibody; low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1) antibody; Lrpap1 antibody; MGC138272 antibody; MRAP antibody; MYP23 antibody; RAP antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Alpha-2-macroglobulin receptor-associated protein (35-357AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類(lèi)型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.
  • 基因功能參考文獻(xiàn):
    1. The clinical and biometric features we describe in this report characterize LRPAP1-related high myopia and should raise suspicion for mutations in the gene. PMID: 26271838
    2. The inhibition caused by reagents that prevented the activation of Rap was reversed by mobilizing intracellular calcium pharmacologically, whereas that caused by acrosome reaction inhibitors that impeded Rab3's binding to GTP was not. PMID: 25159528
    3. The LRPAP1 I allelic variant may be considered a candidate gene for PD, predominantly in patients having the APOE epsilon4 allelic variant. PMID: 24504617
    4. RAP inhibited light chain (LC)endocytosis by approximately 88% and ameliorated LC-induced cytokine responses and epithelial-to-mesenchymal transformation in human proximal tubular cells. PMID: 23894629
    5. Mutations in LRPAP1 are associated with severe myopia in humans. PMID: 23830514
    6. LRP1-C/T, A2M-Ile/Val and APOE-epsilon 2/epsilon 3/epsilon 4 polymorphisms are associated with AD. PMID: 20637261
    7. Findings reveal that RAP is a novel Abeta-binding protein that promotes cellular internalization of Abeta. PMID: 19826010
    8. Adenoviral-mediated expression of human receptor-asociated protein RAP in a murine model of von Willebrand disease results in a continuous rise in FVIII over 6 days. PMID: 11992244
    9. RAP is organized into three domains located in the first third (1D), middle third (2D), and last third (3D) of the protein; all three domains adopt stable tertiary structure as isolated domains and are monomers. PMID: 14674767
    10. NMR structure of domain 1 of receptor-associated protein PMID: 15213425
    11. An insertion allele is found to be associated with gallstone disease. PMID: 16704534
    12. RAP is expressed by thyrocytes in a TSH-dependent manner, both in cultured thyroid cells and in vivo PMID: 17123336
    13. analysis of the relationship between ACE and LRPAP1 gene polymorphisms and age in an Italian population PMID: 17536759
    14. Low-density lipoprotein receptor-related protein-associated protein (LRPAP1) gene IVS5 insertion/deletion polymorphism is not a risk factor for gallstone disease in a Polish population. PMID: 17913606
    15. Low-density lipoprotein receptor-related protein associated protein (LRPAP1) insertion/deletion polymorphism is associated with gallstone disease and gallbladder carcinoma PMID: 17987404
    16. LRP-1/LDLR-mediated uptake of A beta results in degeneration of perivascular cells. PMID: 18055545
    17. alterations of the RAP gene are not a common cause of hypothyroidism PMID: 18075286
    18. Our study suggests that LRPAP1-D and APOE E4 alleles significantly increase the susceptibility to degenerative dementias. PMID: 18721259

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Myopia 23, autosomal recessive (MYP23)
  • 亞細(xì)胞定位:
    Rough endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment lumen. Golgi apparatus, cis-Golgi network. Golgi apparatus lumen. Endosome lumen. Cell surface.
  • 蛋白家族:
    Alpha-2-MRAP family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 6701

    OMIM: 104225

    KEGG: hsa:4043

    STRING: 9606.ENSP00000421922

    UniGene: Hs.40966



主站蜘蛛池模板: 一二三四视频社区在线| 亚洲国产成人精品无码区在线秒播| 国产av激情久久无码天堂 | 中文幕无线码中文字蜜桃| 亚洲一卡2卡3卡4卡 精品| 色婷婷五月综合激情中文字幕| 丰满人妻被黑人中出849| 亚洲精品国男人在线视频| 国产亚洲欧美在线专区| 欧美性受xxxx黑人xyx性爽| 福利姬液液酱喷水| 99久久国语露脸精品国产| 国产成人免费无庶挡视频| 黑人与人妻无码中字视频| 粉嫩极品国产在线观看| 国产免费无遮挡吸乳视频| 中文字幕欧美人妻精品一区 | 国产aⅴ精品一区二区三区久久| 国精品99久9在线 | 免费| 日韩亚洲欧美中文高清在线| 成人aaa片一区国产精品| 国产另类ts人妖一区二区| 亚洲综合无码中文字幕第2页| 亚洲精品在看在线观看| 性做久久久久久久免费看| 亚洲一区av在线观看| 99久久无码一区人妻a片蜜| 国产av偷闻女邻居内裤被发现| 国产日产欧产精品品不卡| 亚洲人成网站在线观看69影院| 色妞色视频一区二区三区四区| 免费无码成人av在线播| 无码专区6080yy国产电影| 国产精品无套呻吟在线| 色噜噜狠狠色综合日日| 成年无码动漫av片在线观看羞羞| 久久久774这里只有精品17| 激情航班h版在线观看| 免费99精品国产自在在线| 亚洲精品久久久一二三区| 丰满少妇被猛烈进入av久久|