在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

LEO1 Antibody, FITC conjugated

  • 中文名稱:
    LEO1兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào):
    CSB-PA845150NC01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) LEO1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    LEO1
  • 別名:
    Gm185 antibody; LEO1 antibody; LEO1_HUMAN antibody; LOC123439 antibody; Paf1/RNA polymerase II complex component antibody; Replicative senescence down regulated leo1 like protein antibody; Replicative senescence down-regulated leo1-like protein antibody; Replicative senescence downregulated leo1 like antibody; RNA polymerase associated protein LEO1 antibody; RNA polymerase-associated protein LEO1 antibody; Senescence downregulated leo1 like antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Peptide sequence from Human RNA polymerase-associated protein LEO1 protein (2-24AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both independently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1; it promotes leukemogenesis through association with KMT2A/MLL1-rearranged oncoproteins, such as KMT2A/MLL1-MLLT3/AF9 and KMT2A/MLL1-MLLT1/ENL. PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 'Lys-4' (H3K4me3). PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1); UB2A/B-mediated H2B ubiquitination is proposed to be coupled to transcription. PAF1C is involved in mRNA 3' end formation probably through association with cleavage and poly(A) factors. In case of infection by influenza A strain H3N2, PAF1C associates with viral NS1 protein, thereby regulating gene transcription. Involved in polyadenylation of mRNA precursors. Connects PAF1C to Wnt signaling.
  • 基因功能參考文獻(xiàn):
    1. PRL-3 and Leo1 levels were positively associated in AML patient samples. PMID: 24686170
    2. Screened glioblastomas and oligodendrogliomas for fusion genes by identifying aberrant 5'-3' expression of genes that lie over regions of a copy number change. A fusion gene between exon 11 of LEO1 and exon 10 of SLC12A1 was identified. PMID: 20196086
  • 亞細(xì)胞定位:
    Nucleus.
  • 蛋白家族:
    LEO1 family
  • 組織特異性:
    Highly expressed in skeletal muscle and heart. Weakly expressed in placenta and liver.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 30401

    OMIM: 610507

    KEGG: hsa:123169

    STRING: 9606.ENSP00000299601

    UniGene: Hs.567662



主站蜘蛛池模板: 日韩在线一区二区三区免费视频| 亚洲色精品三区二区一区| 精品国产青草久久久久福利| 成人综合网站| 黑人粗大猛烈进出高潮视频| 人妻精品久久无码区| 久久99热久久99精品| 亚洲五月综合缴情在线| 99re6热精品视频在线观看| 亚洲欧洲久久av| 精品国产一区二区三区无码 | 狠狠色噜噜狠狠狠888米奇| 日本高清aⅴ毛片免费| 久久九九精品99国产精品 | 中文字幕在线不卡精品视频99 | 成人午夜高潮免费视频在线观看| 国产成人无码视频网站在线观看| 一边吃奶一边摸做爽视频| 中文字幕av无码不卡| 国产精品久久无码不卡黑寡妇| 亚洲第一a在线观看网站| 中国妇女做爰视频| 一本久久综合亚洲鲁鲁五月天| 韩国三级hd中文字幕叫床| 精品无码国产一区二区三区av| 2020精品国产自在现线看 | 成人女人看片免费视频放人| 少妇高潮喷潮久久久影院| 国产成人精品一区二区三区免费看| 日本免费一区二区三区四区五区 | 天堂8а√中文在线官网 | 精品一卡2卡三卡4卡乱码精品视频| 国产男女猛烈无遮挡免费视频网站| 亚洲成av人片一区二区密柚| 亚洲 日本 欧美 中文字幕| 国产成人不卡无码免费视频| 精品人妻av一区二区三区| 久久精品熟女亚州av麻豆| 国产成人av在线一区二区三区 | 丰满多毛少妇做爰视频爽爽和| 乱熟女高潮一区二区在线|