在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. LDB1 Antibody, FITC conjugated

LDB1 Antibody, FITC conjugated

  • 中文名稱：
    LDB1兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA771433LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) LDB1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LDB1
  • 別名：
    Carboxyl Terminal LIM Domain Binding 2 antibody; Carboxyl-terminal LIM domain-binding protein 2 antibody; CLIM 2 antibody; CLIM-2 antibody; hLdb1 antibody; LDB-1 antibody; ldb1 antibody; LDB1_HUMAN antibody; LIM Domain Binding 1 antibody; LIM domain binding factor CLIM2 antibody; LIM domain-binding factor CLIM2 antibody; LIM domain-binding protein 1 antibody; NLI antibody; Nuclear LIM Domain Interactor antibody; Nuclear LIM interactor antibody; xldb1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human LIM domain-binding protein 1 protein (50-375AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state.
  • 基因功能參考文獻(xiàn)：
    1. Data indicate that LIM-domain-binding protein 1 (LDB1) has a strong role in colorectal cancer (CRC) progression. PMID: 27713177
    2. LDB1 maintains the terminally differentiated state of beta cells and is a component of active enhancers in both murine and human islets. PMID: 27941246
    3. SSBP3 Interacts With Islet-1 and Ldb1 to Impact Pancreatic beta-Cell Target Genes PMID: 26495868
    4. Alanine scanning mutagenesis of the LIM interaction domain of LDB1 revealed a discrete motif, R(320)LITR, required for LMO2 binding. PMID: 26598604
    5. In t(8;21) leukemia cells, LDB1 functions as a component of the stable AML1-ETO-containing transcription factor complex (AETFC). The AETFC components cooperatively regulate gene expression and contribute to leukemogenesis. PMID: 23812588
    6. We investigated NLI (Ldb1 homolog) complex occupancy and chromatin conformation of the beta-globin locus in human erythroid cells. PMID: 22010104
    7. These studies are consistent with a model in which TIF1gamma acts to ubiquitinate LDB1 leading to degradation of LDB1 and changes in transcription of LDB1-dependent promoters. PMID: 20447379
    8. Expression of LDB1 (LIM-domain-binding 1) protein in which Lys134 is replaced with arginine leads to enhanced expression of the mutant protein compared with the wild-type protein. PMID: 20423330
    9. Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate development PMID: 12381786
    10. characterize the assembly of a five-component complex containing TAL1, LMO2, Ldb1, E12, and DNA. The bHLH domains of TAL1 and E12 alone primarily formed helical homodimers, but together formed heterodimers, to which LMO2 bound with high affinity PMID: 17910069

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    LDB family
  • 組織特異性：
    Expressed in a wide range of adult tissues including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, lung and peripheral blood leukocytes.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 6532

    OMIM: 603451

    KEGG: hsa:8861

    STRING: 9606.ENSP00000392466

    UniGene: Hs.454418



主站蜘蛛池模板： 天天狠天天透天天伊人| 国产成人一区二区无码不卡在线 | 午夜人性色福利无码视频在线观看| 午夜无码人妻av大片色欲| 午夜福利视频| 7878成人国产在线观看| 亚洲 综合 欧美在线视频| 亚洲精品无码久久毛片波多野吉衣| 国产乱子伦在线一区二区| 性欧美欧美巨大69| 蜜桃成人无码区免费视频网站| 久久久774这里只有精品17| 奇米影视7777狠狠狠狠影视| .精品久久久麻豆国产精品| 国产精品无码久久久久成人影院| 亚洲大乳高潮日本专区| 成 人 社区在线视频| 国产欧美va天堂在线观看视频下载| 亚洲中文字幕久久无码| 国产美女视频免费观看的网站| 天天爽天天狠久久久综合麻豆 | 亚洲日韩欧美一区二区三区在线| 国产成 人 综合 亚洲网站| 国产99久久精品一区二区| 中文字幕久久熟女蜜桃| 亚洲中文字幕在线第二页| 成年片色大黄全免费网站久久高潮| 国产色婷婷亚洲99精品小说 | 国产极品美女到高潮| 久久久国产99久久国产久麻豆| 亚洲精品网站在线观看你懂的 | 三男一女吃奶添下面视频| 久久天天躁夜夜躁狠狠i女人| 在线精品视频一区二区三四| 男女无遮挡xx00动态图120秒| 色播久久人人爽人人爽人人片av| 亚洲伊人久久大香线蕉| 公与淑婷厨房猛烈进出视频免费| 理论片午午伦夜理片影院99| 偷看农村女人做爰毛片色| 亚洲图片校园另激情类小说|