在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. LDB1 Antibody, Biotin conjugated

LDB1 Antibody, Biotin conjugated

  • 中文名稱：
    LDB1兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA771433LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) LDB1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LDB1
  • 別名：
    Carboxyl Terminal LIM Domain Binding 2 antibody; Carboxyl-terminal LIM domain-binding protein 2 antibody; CLIM 2 antibody; CLIM-2 antibody; hLdb1 antibody; LDB-1 antibody; ldb1 antibody; LDB1_HUMAN antibody; LIM Domain Binding 1 antibody; LIM domain binding factor CLIM2 antibody; LIM domain-binding factor CLIM2 antibody; LIM domain-binding protein 1 antibody; NLI antibody; Nuclear LIM Domain Interactor antibody; Nuclear LIM interactor antibody; xldb1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human LIM domain-binding protein 1 protein (50-375AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state.
  • 基因功能參考文獻：
    1. Data indicate that LIM-domain-binding protein 1 (LDB1) has a strong role in colorectal cancer (CRC) progression. PMID: 27713177
    2. LDB1 maintains the terminally differentiated state of beta cells and is a component of active enhancers in both murine and human islets. PMID: 27941246
    3. SSBP3 Interacts With Islet-1 and Ldb1 to Impact Pancreatic beta-Cell Target Genes PMID: 26495868
    4. Alanine scanning mutagenesis of the LIM interaction domain of LDB1 revealed a discrete motif, R(320)LITR, required for LMO2 binding. PMID: 26598604
    5. In t(8;21) leukemia cells, LDB1 functions as a component of the stable AML1-ETO-containing transcription factor complex (AETFC). The AETFC components cooperatively regulate gene expression and contribute to leukemogenesis. PMID: 23812588
    6. We investigated NLI (Ldb1 homolog) complex occupancy and chromatin conformation of the beta-globin locus in human erythroid cells. PMID: 22010104
    7. These studies are consistent with a model in which TIF1gamma acts to ubiquitinate LDB1 leading to degradation of LDB1 and changes in transcription of LDB1-dependent promoters. PMID: 20447379
    8. Expression of LDB1 (LIM-domain-binding 1) protein in which Lys134 is replaced with arginine leads to enhanced expression of the mutant protein compared with the wild-type protein. PMID: 20423330
    9. Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate development PMID: 12381786
    10. characterize the assembly of a five-component complex containing TAL1, LMO2, Ldb1, E12, and DNA. The bHLH domains of TAL1 and E12 alone primarily formed helical homodimers, but together formed heterodimers, to which LMO2 bound with high affinity PMID: 17910069

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    LDB family
  • 組織特異性：
    Expressed in a wide range of adult tissues including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, lung and peripheral blood leukocytes.
  • 數據庫鏈接：

    HGNC: 6532

    OMIM: 603451

    KEGG: hsa:8861

    STRING: 9606.ENSP00000392466

    UniGene: Hs.454418



主站蜘蛛池模板： 久久久久久妓女精品影院| 国产成人av激情在线播放| 国产亚洲精品美女在线| 国产午夜精品一二区理论影院| 香蕉在线 亚洲 欧美 专区| 日韩欧美国产一区精品| 国产免费极品av吧在线观看| 日本阿v网站在线观看中文| 国产精品久久人妻无码网站一区 | 亚拍精品一区二区三区探花 | 真人作爱免费视频| 国产麻豆放荡av剧情演绎| 亚洲精品卡2卡3卡4卡5卡区| 亚洲 欧美 另类 综合 日韩| 久久理论片午夜琪琪电影院| 少妇私密推油呻吟在线播放| 无码少妇一区二区三区| 东北女人毛多水多牲交视频| 秋霞电影网午夜鲁丝片无码| 色噜噜亚洲男人的天堂www| 超薄肉色丝袜一区二区| 性生交大片免费看女人按摩| 天天爽夜夜爽夜夜爽精品视频| 三级做a全过程在线观看| 18禁超污无遮挡无码免费网站国产| 2023国产精品一卡2卡三卡4卡| 久久久久久久97| 含紧一点h边做边走动免费视频| 国产精品狼人久久久久影院| 欧美人与动zozo在线播放| 性色欲情网站iwww九文堂| 亚洲 小说 欧美 激情 另类| 国产日韩精品一区二区三区在线| 亚洲一区二区三区在线观看网站| 青青草国产三级精品三级 | 精品久久人人爽天天玩人人妻| 深夜国产一区二区三区在线看| 被技师按摩到高潮的少妇| 在线观看片a免费不卡观看| 性xxxx搡xxxxx搡欧美| 中国女人大白屁股ass|