在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. LARS Antibody

LARS Antibody

  • 中文名稱：
    LARS兔多克隆抗體
  • 貨號：
    CSB-PA012757GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    LARS
  • 別名：
    cytoplasmic antibody; Cytoplasmic leucyl tRNA synthetase antibody; Cytosolic leucyl tRNA synthetase antibody; FLJ10595 antibody; FLJ21788 antibody; hr025Cl antibody; HSPC 192 antibody; HSPC192 antibody; KIAA1352 antibody; LARS 1 antibody; Lars antibody; LARS1 antibody; Leucine translase antibody; Leucine tRNA ligase antibody; Leucine--tRNA ligase antibody; Leucyl tRNA synthetase cytoplasmic antibody; Leucyl-tRNA synthetase antibody; LeuRS antibody; LEUS antibody; LRS antibody; PIG 44 antibody; PIG44 antibody; Proliferation inducing gene 44 antibody; RNTLS antibody; SYLC_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human LARS
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC,IF
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs.
  • 基因功能參考文獻(xiàn)：
    1. Leucyl-tRNA synthetase (LRS) is a leucine sensor of the mTORC1 pathway. PMID: 28963468
    2. The results showed a decrease in autophagy on addition of leucine, demonstrating crosstalk between leucine sensing, LRS translocation, RagD interaction, and mTORC1 activation. PMID: 28882589
    3. the KMSKS catalytic loop affects the aminoacylation and editing capacities of leucyl-tRNA synthetase PMID: 25817995
    4. Lack of a CP1 hairpin in LeuRS led to complete loss of aminoacylation, amino acid activation, and tRNA binding; however, the mutants retained post-transfer editing. PMID: 25051973
    5. the carboxy-terminal domain of human mitochondrial (mt) leucyl-tRNA synthetase can be used to correct mt dysfunctions caused by mt-tRNA mutations. PMID: 24413190
    6. Identification of a mutation in LARS as a novel cause of infantile hepatopathy PMID: 22607940
    7. This work demonstrates that LRS is a key mediator for amino acid signaling to mTORC1. PMID: 22424946
    8. hcLeuRS can charge RNALeu with non-cognate amino acids and exclude the incorrect products by multiple editing pathways. PMID: 20805241
    9. leucyl-tRNA synthetase requires its C-terminal domain for its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex PMID: 16055448
    10. We identified a novel G3283A transition in the mitochondrial DNA tRNA(Leu (UUR)) gene in a patient with ptosis, ophthalmoparesis and hyporeflexia. PMID: 17363246
    11. Results show that K600 in human leucyl-tRNA synthetase affects amino acid specificity and tRNA aminoacylation. PMID: 17378584
    12. findings suggest that LARS1 may play roles in migration and growth of lung cancer cells, which suggest its potential implication in lung tumorigenesis PMID: 18446061
    13. Study of crystal structures of the editing domain from 2 eukaryotic cytosolic LeuRS; shows a conserved structural core containing the active site for hydrolysis, with distinct bacterial, archeal, or eukaryotic peripheral insertions. PMID: 19426743
    14. the introduction of bulky residues into the amino acid binding pocket failed to block deacylation of tRNA, indicating that the architecture of the amino acid binding pocket is different compared to that of other characterized LeuRSs PMID: 19702327

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Infantile liver failure syndrome 1 (ILFS1)
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    Class-I aminoacyl-tRNA synthetase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 6512

    OMIM: 151350

    KEGG: hsa:51520

    STRING: 9606.ENSP00000377954

    UniGene: Hs.432674



主站蜘蛛池模板： 无码里番纯肉h在线网站| 日韩欧国产精品一区综合无码| 成人毛片av免费| 激情国产av做激情国产爱| 久久久国产精品人人片| 内射囯产旡码丰满少妇| 国产偷国产偷亚洲清高| 最近中文字幕免费大全在线| 蜜桃麻豆www久久国产sex| 特级西西人体444www高清大胆| 精品久久久无码人妻字幂| 国产av无码专区亚洲精品| 久久精品国产99久久无毒不卡| 又色又爽又黄的视频国内| 成年女性特黄午夜视频免费看| 国产精品国产三级国产aⅴ下载| 青青草国产精品欧美成人| 少妇大胆瓣开下部自慰| 国产亚洲精品成人aa片新蒲金| 特大巨黑吊xxxx高潮| 中国熟妇牲交视频| 2021国产精品香蕉在线观看| 久久中文骚妇内射| 久久天天躁夜夜躁狠狠85麻豆| 亚洲最大成人综合网720p| 护士张开腿被奷日出白浆| 亚洲蜜芽在线精品一区| 国内精品人妻无码久久久影院蜜桃| 97午夜理论片在线影院| 性色a∨人人爽网站hdkp885| 欧美大香线蕉线伊人久久| 无套中出极品少妇白浆| 中文综合在线观| 18禁黄网站禁片无遮挡观看| 老女老肥熟国产在线视频| 亚洲中文无码av在线| 亚洲一区二区三区在线播放无码| 亚洲精品乱码一区二区三区| 国产内射爽爽大片| 日本丰满白嫩大屁股ass| 99精品热在线在线观看视频|