在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. LARS Antibody

LARS Antibody

  • 中文名稱：
    LARS兔多克隆抗體
  • 貨號：
    CSB-PA012757GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    LARS
  • 別名：
    cytoplasmic antibody; Cytoplasmic leucyl tRNA synthetase antibody; Cytosolic leucyl tRNA synthetase antibody; FLJ10595 antibody; FLJ21788 antibody; hr025Cl antibody; HSPC 192 antibody; HSPC192 antibody; KIAA1352 antibody; LARS 1 antibody; Lars antibody; LARS1 antibody; Leucine translase antibody; Leucine tRNA ligase antibody; Leucine--tRNA ligase antibody; Leucyl tRNA synthetase cytoplasmic antibody; Leucyl-tRNA synthetase antibody; LeuRS antibody; LEUS antibody; LRS antibody; PIG 44 antibody; PIG44 antibody; Proliferation inducing gene 44 antibody; RNTLS antibody; SYLC_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human LARS
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC,IF
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs.
  • 基因功能參考文獻(xiàn)：
    1. Leucyl-tRNA synthetase (LRS) is a leucine sensor of the mTORC1 pathway. PMID: 28963468
    2. The results showed a decrease in autophagy on addition of leucine, demonstrating crosstalk between leucine sensing, LRS translocation, RagD interaction, and mTORC1 activation. PMID: 28882589
    3. the KMSKS catalytic loop affects the aminoacylation and editing capacities of leucyl-tRNA synthetase PMID: 25817995
    4. Lack of a CP1 hairpin in LeuRS led to complete loss of aminoacylation, amino acid activation, and tRNA binding; however, the mutants retained post-transfer editing. PMID: 25051973
    5. the carboxy-terminal domain of human mitochondrial (mt) leucyl-tRNA synthetase can be used to correct mt dysfunctions caused by mt-tRNA mutations. PMID: 24413190
    6. Identification of a mutation in LARS as a novel cause of infantile hepatopathy PMID: 22607940
    7. This work demonstrates that LRS is a key mediator for amino acid signaling to mTORC1. PMID: 22424946
    8. hcLeuRS can charge RNALeu with non-cognate amino acids and exclude the incorrect products by multiple editing pathways. PMID: 20805241
    9. leucyl-tRNA synthetase requires its C-terminal domain for its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex PMID: 16055448
    10. We identified a novel G3283A transition in the mitochondrial DNA tRNA(Leu (UUR)) gene in a patient with ptosis, ophthalmoparesis and hyporeflexia. PMID: 17363246
    11. Results show that K600 in human leucyl-tRNA synthetase affects amino acid specificity and tRNA aminoacylation. PMID: 17378584
    12. findings suggest that LARS1 may play roles in migration and growth of lung cancer cells, which suggest its potential implication in lung tumorigenesis PMID: 18446061
    13. Study of crystal structures of the editing domain from 2 eukaryotic cytosolic LeuRS; shows a conserved structural core containing the active site for hydrolysis, with distinct bacterial, archeal, or eukaryotic peripheral insertions. PMID: 19426743
    14. the introduction of bulky residues into the amino acid binding pocket failed to block deacylation of tRNA, indicating that the architecture of the amino acid binding pocket is different compared to that of other characterized LeuRSs PMID: 19702327

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Infantile liver failure syndrome 1 (ILFS1)
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    Class-I aminoacyl-tRNA synthetase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 6512

    OMIM: 151350

    KEGG: hsa:51520

    STRING: 9606.ENSP00000377954

    UniGene: Hs.432674



主站蜘蛛池模板： 国产精品∧v在线观看| 久久亚洲精品国产亚洲老地址| 久热这里只精品99国产6-99re视…| 成人做爰视频www网站| 亚洲国产中文在线视频| 四虎影库在线永久影院免费观看| 97人妻人人揉人人躁人人| 婷婷久久综合九色综合绿巨人| 4480yy私人精品国产| 裸体丰满白嫩大尺度尤物| 久久偷看各类wc女厕嘘嘘偷窃| 肥臀浪妇太爽了快点再快点 | 97一期涩涩97片久久久久久久| 国产精华av午夜在线观看| 亚洲一区二区三区四区| 日韩精品无码一区二区三区| 97精品久久天干天天| 尤物tv国产精品看片在线| 777午夜福利理论电影网| 先锋影音最新色资源站| 免费精品国偷自产在线在线| 一本清日本在线视频精品| 日日碰狠狠躁久久躁| 波多野结衣 黑人| 蜜臀av色欲a片无人一区| 天堂中文在线8最新版地址| 欧美老熟妇videos极品另类| 少妇高潮太爽了在线观看| 日韩精品无码人成视频| 青青草原精品99久久精品66| 黑人大荫蒂高潮视频| 国产亚洲精品久久久久9999| 137肉体摄影日本裸交| 亚洲精品一区二区三区四区五区| 久久久精品2020免费观看| 亚洲欧美在线制服丝袜国产| 8888四色奇米在线观看| 夜夜爽一区二区三区精品| av免费播放一区二区三区| 清纯小美女主播流白浆| 久久99精品久久久久久水蜜桃|