在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. KLF13 Antibody

KLF13 Antibody

  • 中文名稱(chēng)：
    KLF13兔多克隆抗體
  • 貨號(hào)：
    CSB-PA012387GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    KLF13
  • 別名：
    Basic transcription element binding protein 3 antibody; Basic transcription element-binding protein 3 antibody; BTE binding protein 3 antibody; BTE-binding protein 3 antibody; BTEB3 antibody; C2 H2 zinc finger protein antibody; FKLF 2 antibody; FKLF2 antibody; Klf13 antibody; KLF13_HUMAN antibody; Krueppel-like factor 13 antibody; Kruppel like factor 13 antibody; Novel Sp1 like zinc finger transcription factor antibody; Novel Sp1-like zinc finger transcription factor 1 antibody; NSLP1 antibody; RANTES factor of late activated T lymphocytes 1 antibody; RANTES factor of late activated T-lymphocytes 1 antibody; RFLAT 1 antibody; RFLAT-1 antibody; RFLAT1 antibody; Transcription factor BTEB3 antibody; Transcription factor NSLP1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human KLF13
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells.
  • 基因功能參考文獻(xiàn)：
    1. Results show that cg07814318 methylation in blood was significantly associated with obesity and correlated with several obesity-related physical and biochemical traits. The exome sequencing of KLF13 gene in blood identified nine SNPs within its gene body, and two SNPs as cis-meQTL of cg07814318. The sequencing variations within KLF13 genes could drive dynamic modifications of obesity-related CpG methylation. PMID: 28508896
    2. KLF13 functions as a tumor suppressor protein in PCa, and the pharmacological activation of KLF13 might represent a potential approach for the treatment of prostate cancer. PMID: 29843216
    3. Our results suggest the cg07814318 site could be involved in orexigenic processes, and also implicate KLF13 in obesity. Our findings are the first to associate methylation levels in blood with brain activity in obesity-related regions, and further support previous findings between ghrelin, brain activity and genetic differences. PMID: 28194012
    4. KLF13 is critical for the activation of the HPV productive life cycle and is likely involved in initiation and progression of cervical cancer. PMID: 27041562
    5. Knockdown of either FBW7gamma or GSK3beta by small interfering RNA increases KLF13 expression in resting human T lymphocytes. PMID: 22797700
    6. No associations were found between maternal genetic polymorphisms in RANTES (-403G/A) and mother-to-child HIV-1 transmission; plasma, cervical and breastmilk viral loads; or breastmilk chemokine concentrations. PMID: 20518834
    7. KLF13 contributes to malignancy in oral cancer cells and may be a useful biomarker fo early detection and da possible target for therapy. PMID: 20539070
    8. Data support cross-regulation among BMP2, KLF9, and KLF13 to maintain progesterone sensitivity in stromal cells undergoing differentiation and suggest that loss of this network compromises establishment of uterine receptivity and implantation success. PMID: 20410205
    9. protein analysis of BTEB3 and BTEB4 and their binding to CYP1A1 PMID: 12036432
    10. functional domains and DNA-binding sequences PMID: 12050170
    11. A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes. PMID: 12093895
    12. Feedback mechanism for the transcriptional control of the KLF13 gene in the erythroid environment. PMID: 15716005
    13. KLF13 is a key regulator of late RANTES expression in T lymphocytes PMID: 17074812
    14. Coexpression of PRP4 and KLF13 increases nuclear localization of KLF13 and CCL5 transcription. PMID: 17513757
    15. Transient transfection of Kruppel-like factor 4 suppressed LDLR, steroidogenic acute regulatory protein, and CYP11A PMID: 18056793

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    Sp1 C2H2-type zinc-finger protein family
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 13672

    OMIM: 605328

    KEGG: hsa:51621

    STRING: 9606.ENSP00000302456

    UniGene: Hs.376443



主站蜘蛛池模板： 玩弄少妇人妻| 免费观看一区二区三区 | 免费国产黄网站在线观看| 国产午夜精品理论片| 国产精品白丝久久av网站| 国产色诱视频在线播放网站| 亚洲成av人片一区二区梦乃| 可以看三级的网站| 免费人妻精品一区二区三区 | 免费午夜福利不卡片在线播放 | 国产精品高清一区二区不卡片| 国产a v高清一区二区三区| 亚洲丰满熟女一区二区v| 国产97在线 | 亚洲| 在线不卡日本v二区到六区| 亚洲 卡通 欧美 制服 中文| 国产成人a区在线观看视频| 熟妇与小伙子matur老熟妇e| 精品无码久久久久国产手机版| 中文字幕在线精品视频入口一区| 中文国产成人精品久久app| 亚洲国产成人久久综合一区| 人妻洗澡被强公日日澡电影| 免费无码av片在线观看网址| 国产手机在线无码播放视频| 无码不卡av东京热毛片| 国产精品点击进入在线影院高清 | 日本又色又爽又黄的视频免| 西欧free性满足hd| 麻豆一区二区在我观看| 天堂在/线资源中文在线| 亚洲人禽杂交av片久久| 野外亲子乱子伦视频丶| 亚洲国产一区二区三区| 国产精品久久国产精品99盘| 18禁成人黄网站免费观看久久| 国产成人精品久久亚洲高清不卡| 亚洲第一成年免费网站| 日本三级在线播放线观看视频| 久久精品国产99精品国产2021| 不卡无码av一区二区三区|