在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. KLF13 Antibody, HRP conjugated

KLF13 Antibody, HRP conjugated

  • 中文名稱：
    KLF13兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA897476LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) KLF13 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KLF13
  • 別名：
    Basic transcription element binding protein 3 antibody; Basic transcription element-binding protein 3 antibody; BTE binding protein 3 antibody; BTE-binding protein 3 antibody; BTEB3 antibody; C2 H2 zinc finger protein antibody; FKLF 2 antibody; FKLF2 antibody; Klf13 antibody; KLF13_HUMAN antibody; Krueppel-like factor 13 antibody; Kruppel like factor 13 antibody; Novel Sp1 like zinc finger transcription factor antibody; Novel Sp1-like zinc finger transcription factor 1 antibody; NSLP1 antibody; RANTES factor of late activated T lymphocytes 1 antibody; RANTES factor of late activated T-lymphocytes 1 antibody; RFLAT 1 antibody; RFLAT-1 antibody; RFLAT1 antibody; Transcription factor BTEB3 antibody; Transcription factor NSLP1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Krueppel-like factor 13 protein (26-147AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells.
  • 基因功能參考文獻：
    1. Results show that cg07814318 methylation in blood was significantly associated with obesity and correlated with several obesity-related physical and biochemical traits. The exome sequencing of KLF13 gene in blood identified nine SNPs within its gene body, and two SNPs as cis-meQTL of cg07814318. The sequencing variations within KLF13 genes could drive dynamic modifications of obesity-related CpG methylation. PMID: 28508896
    2. KLF13 functions as a tumor suppressor protein in PCa, and the pharmacological activation of KLF13 might represent a potential approach for the treatment of prostate cancer. PMID: 29843216
    3. Our results suggest the cg07814318 site could be involved in orexigenic processes, and also implicate KLF13 in obesity. Our findings are the first to associate methylation levels in blood with brain activity in obesity-related regions, and further support previous findings between ghrelin, brain activity and genetic differences. PMID: 28194012
    4. KLF13 is critical for the activation of the HPV productive life cycle and is likely involved in initiation and progression of cervical cancer. PMID: 27041562
    5. Knockdown of either FBW7gamma or GSK3beta by small interfering RNA increases KLF13 expression in resting human T lymphocytes. PMID: 22797700
    6. No associations were found between maternal genetic polymorphisms in RANTES (-403G/A) and mother-to-child HIV-1 transmission; plasma, cervical and breastmilk viral loads; or breastmilk chemokine concentrations. PMID: 20518834
    7. KLF13 contributes to malignancy in oral cancer cells and may be a useful biomarker fo early detection and da possible target for therapy. PMID: 20539070
    8. Data support cross-regulation among BMP2, KLF9, and KLF13 to maintain progesterone sensitivity in stromal cells undergoing differentiation and suggest that loss of this network compromises establishment of uterine receptivity and implantation success. PMID: 20410205
    9. protein analysis of BTEB3 and BTEB4 and their binding to CYP1A1 PMID: 12036432
    10. functional domains and DNA-binding sequences PMID: 12050170
    11. A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes. PMID: 12093895
    12. Feedback mechanism for the transcriptional control of the KLF13 gene in the erythroid environment. PMID: 15716005
    13. KLF13 is a key regulator of late RANTES expression in T lymphocytes PMID: 17074812
    14. Coexpression of PRP4 and KLF13 increases nuclear localization of KLF13 and CCL5 transcription. PMID: 17513757
    15. Transient transfection of Kruppel-like factor 4 suppressed LDLR, steroidogenic acute regulatory protein, and CYP11A PMID: 18056793

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Sp1 C2H2-type zinc-finger protein family
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 13672

    OMIM: 605328

    KEGG: hsa:51621

    STRING: 9606.ENSP00000302456

    UniGene: Hs.376443



主站蜘蛛池模板： 暴力强奷在线播放无码| 婷婷五月深爱憿情网| 日本中文字幕乱码aa高清电影| 午夜爱爱爱爱爽爽爽网站| 日韩欧群交p片内射中文| 国产乱子轮xxx农村| 国产精品无码a∨精品影院app| 亚洲综合久久成人a片红豆| 国产精品久久久久久不卡盗摄| 熟妇与小伙子matur老熟妇e| 国产亚洲精品久久久久久打不开| 成人一在线视频日韩国产| 国产手机在线无码播放视频| 人妻丰满熟妇aⅴ无码| 国产亚洲精品97在线视频一| 春药高潮抽搐流白浆在线观看| 在线观看无码av免费不卡软件| 亚洲va中文字幕| 中国女人大白屁股ass| 亚洲一区二区无码影院| 精品无码一区二区三区av| 俺也来俺也去俺也射| 天堂网www天堂在线资源| 欧洲美熟女乱又伦av| 国产无套精品一区二区三区| 亚洲乱亚洲乱妇24p| 色惰日本视频网站www| 久久精品国产一区二区电影| 久久久www免费人成精品| 欧美性猛交xxx嘿人猛交| 久久av高潮av无码av| 新国产三级视频在线播放| 欧美变态暴力牲交videos| 国产精品嫩草99av在线| 亚洲熟妇色xxxxx欧美老妇y| 国产后入清纯学生妹 | 久久九九有精品国产23百花影院 | 国产精品美女久久久久av爽| 日本乱妇乱子视频网站-百度| 青草久久人人97超碰| 一卡二卡3卡四卡网站精品|