在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. KLF13 Antibody, FITC conjugated

KLF13 Antibody, FITC conjugated

  • 中文名稱：
    KLF13兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA897476LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) KLF13 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KLF13
  • 別名：
    Basic transcription element binding protein 3 antibody; Basic transcription element-binding protein 3 antibody; BTE binding protein 3 antibody; BTE-binding protein 3 antibody; BTEB3 antibody; C2 H2 zinc finger protein antibody; FKLF 2 antibody; FKLF2 antibody; Klf13 antibody; KLF13_HUMAN antibody; Krueppel-like factor 13 antibody; Kruppel like factor 13 antibody; Novel Sp1 like zinc finger transcription factor antibody; Novel Sp1-like zinc finger transcription factor 1 antibody; NSLP1 antibody; RANTES factor of late activated T lymphocytes 1 antibody; RANTES factor of late activated T-lymphocytes 1 antibody; RFLAT 1 antibody; RFLAT-1 antibody; RFLAT1 antibody; Transcription factor BTEB3 antibody; Transcription factor NSLP1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Krueppel-like factor 13 protein (26-147AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells.
  • 基因功能參考文獻：
    1. Results show that cg07814318 methylation in blood was significantly associated with obesity and correlated with several obesity-related physical and biochemical traits. The exome sequencing of KLF13 gene in blood identified nine SNPs within its gene body, and two SNPs as cis-meQTL of cg07814318. The sequencing variations within KLF13 genes could drive dynamic modifications of obesity-related CpG methylation. PMID: 28508896
    2. KLF13 functions as a tumor suppressor protein in PCa, and the pharmacological activation of KLF13 might represent a potential approach for the treatment of prostate cancer. PMID: 29843216
    3. Our results suggest the cg07814318 site could be involved in orexigenic processes, and also implicate KLF13 in obesity. Our findings are the first to associate methylation levels in blood with brain activity in obesity-related regions, and further support previous findings between ghrelin, brain activity and genetic differences. PMID: 28194012
    4. KLF13 is critical for the activation of the HPV productive life cycle and is likely involved in initiation and progression of cervical cancer. PMID: 27041562
    5. Knockdown of either FBW7gamma or GSK3beta by small interfering RNA increases KLF13 expression in resting human T lymphocytes. PMID: 22797700
    6. No associations were found between maternal genetic polymorphisms in RANTES (-403G/A) and mother-to-child HIV-1 transmission; plasma, cervical and breastmilk viral loads; or breastmilk chemokine concentrations. PMID: 20518834
    7. KLF13 contributes to malignancy in oral cancer cells and may be a useful biomarker fo early detection and da possible target for therapy. PMID: 20539070
    8. Data support cross-regulation among BMP2, KLF9, and KLF13 to maintain progesterone sensitivity in stromal cells undergoing differentiation and suggest that loss of this network compromises establishment of uterine receptivity and implantation success. PMID: 20410205
    9. protein analysis of BTEB3 and BTEB4 and their binding to CYP1A1 PMID: 12036432
    10. functional domains and DNA-binding sequences PMID: 12050170
    11. A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes. PMID: 12093895
    12. Feedback mechanism for the transcriptional control of the KLF13 gene in the erythroid environment. PMID: 15716005
    13. KLF13 is a key regulator of late RANTES expression in T lymphocytes PMID: 17074812
    14. Coexpression of PRP4 and KLF13 increases nuclear localization of KLF13 and CCL5 transcription. PMID: 17513757
    15. Transient transfection of Kruppel-like factor 4 suppressed LDLR, steroidogenic acute regulatory protein, and CYP11A PMID: 18056793

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Sp1 C2H2-type zinc-finger protein family
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 13672

    OMIM: 605328

    KEGG: hsa:51621

    STRING: 9606.ENSP00000302456

    UniGene: Hs.376443



主站蜘蛛池模板： 国产精品福利一区二区久久| 香港三级日本三级妇三级| 忘忧草www中文在线资源| 蜜色欲多人av久久无码| 欧美性大战xxxxx久久久√| 国产精品久久久久久福利| 免费三级现频在线观看免费| 亚欧无线一线二线三线区别| 欧美日韩亚洲tv不卡久久| 亚洲人成网站18禁止中文字幕| 夜夜高潮夜夜爽国产伦精品| 久久人妻少妇嫩草av蜜桃 | 免费网禁国产you女网站下载| 激烈的性高湖波多野结衣| 欧美综合天天夜夜久久| 国产精品嫩草影院av| 女乱高潮久久久久久爽爽| 中国丰满熟妇av| 三上悠亚ssⅰn939无码播放| 国产精品久久久久久久9999| 奇米777四色在线精品| 欧美两根一起进3p在线观看| 乱人伦人妻中文字幕无码| 无码高潮少妇毛多水多水免费| 久久亚洲精品成人av二次元| 国产在线观看www污污污| 中国极品少妇videossexhd| 无码一区二区波多野结衣播放搜索 | 国内少妇毛片视频| 18禁无遮挡无码网站免费| 伊伊人成亚洲综合人网| 精品人妻无码区二区三区| 无码人妻熟妇av又粗又大 | 欧美黑人又粗又大又爽免费| 国产午夜福利在线观看红一片| 高潮毛片无遮挡高清免费视频| 日本又黄又爽gif动态图| 中文字幕乱码在线播放| 国产亚洲产品影视在线产品| 亚洲中文字幕日产无码2020| 男受被做哭激烈娇喘gv视频|