在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. KLF13 Antibody, FITC conjugated

KLF13 Antibody, FITC conjugated

  • 中文名稱：
    KLF13兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA897476LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) KLF13 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KLF13
  • 別名：
    Basic transcription element binding protein 3 antibody; Basic transcription element-binding protein 3 antibody; BTE binding protein 3 antibody; BTE-binding protein 3 antibody; BTEB3 antibody; C2 H2 zinc finger protein antibody; FKLF 2 antibody; FKLF2 antibody; Klf13 antibody; KLF13_HUMAN antibody; Krueppel-like factor 13 antibody; Kruppel like factor 13 antibody; Novel Sp1 like zinc finger transcription factor antibody; Novel Sp1-like zinc finger transcription factor 1 antibody; NSLP1 antibody; RANTES factor of late activated T lymphocytes 1 antibody; RANTES factor of late activated T-lymphocytes 1 antibody; RFLAT 1 antibody; RFLAT-1 antibody; RFLAT1 antibody; Transcription factor BTEB3 antibody; Transcription factor NSLP1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Krueppel-like factor 13 protein (26-147AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells.
  • 基因功能參考文獻：
    1. Results show that cg07814318 methylation in blood was significantly associated with obesity and correlated with several obesity-related physical and biochemical traits. The exome sequencing of KLF13 gene in blood identified nine SNPs within its gene body, and two SNPs as cis-meQTL of cg07814318. The sequencing variations within KLF13 genes could drive dynamic modifications of obesity-related CpG methylation. PMID: 28508896
    2. KLF13 functions as a tumor suppressor protein in PCa, and the pharmacological activation of KLF13 might represent a potential approach for the treatment of prostate cancer. PMID: 29843216
    3. Our results suggest the cg07814318 site could be involved in orexigenic processes, and also implicate KLF13 in obesity. Our findings are the first to associate methylation levels in blood with brain activity in obesity-related regions, and further support previous findings between ghrelin, brain activity and genetic differences. PMID: 28194012
    4. KLF13 is critical for the activation of the HPV productive life cycle and is likely involved in initiation and progression of cervical cancer. PMID: 27041562
    5. Knockdown of either FBW7gamma or GSK3beta by small interfering RNA increases KLF13 expression in resting human T lymphocytes. PMID: 22797700
    6. No associations were found between maternal genetic polymorphisms in RANTES (-403G/A) and mother-to-child HIV-1 transmission; plasma, cervical and breastmilk viral loads; or breastmilk chemokine concentrations. PMID: 20518834
    7. KLF13 contributes to malignancy in oral cancer cells and may be a useful biomarker fo early detection and da possible target for therapy. PMID: 20539070
    8. Data support cross-regulation among BMP2, KLF9, and KLF13 to maintain progesterone sensitivity in stromal cells undergoing differentiation and suggest that loss of this network compromises establishment of uterine receptivity and implantation success. PMID: 20410205
    9. protein analysis of BTEB3 and BTEB4 and their binding to CYP1A1 PMID: 12036432
    10. functional domains and DNA-binding sequences PMID: 12050170
    11. A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes. PMID: 12093895
    12. Feedback mechanism for the transcriptional control of the KLF13 gene in the erythroid environment. PMID: 15716005
    13. KLF13 is a key regulator of late RANTES expression in T lymphocytes PMID: 17074812
    14. Coexpression of PRP4 and KLF13 increases nuclear localization of KLF13 and CCL5 transcription. PMID: 17513757
    15. Transient transfection of Kruppel-like factor 4 suppressed LDLR, steroidogenic acute regulatory protein, and CYP11A PMID: 18056793

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Sp1 C2H2-type zinc-finger protein family
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 13672

    OMIM: 605328

    KEGG: hsa:51621

    STRING: 9606.ENSP00000302456

    UniGene: Hs.376443



主站蜘蛛池模板： 久久精品女人天堂av| 超碰cao已满18进入离开官网 | 久久精品国产福利一区二区| 国产日韩另类综合11页| 色欲来吧来吧天天综合网| 国产精品99爱免费视频| 欧美精品videossex少妇| 高潮毛片无遮挡高清免费| 又黄又爽吃奶视频在线观看 | 中文无码精品a∨在线观看| 青椒国产97在线熟女| 人妻体验按摩到忍不住哀求继续| 国产人妖视频一区二区| 国产成人精品a视频一区| 中文字幕一二三区波多野结衣| 日本wv一本一道久久香蕉| 久久人妻夜夜做天天爽| 色狠狠av老熟女| 国产97色在线 | 国产| 在线 亚洲 国产 欧美| 成人免费无码视频在线网站 | 日本国产一区二区三区在线观看| 亚洲人色婷婷成人网站在线观看| 成人无码免费一区二区三区| 国产精品日日做人人爱| 久热在线这里只有精品国产| 18禁黄久久久aaa片| 日韩a∨精品日韩在线观看| 国内精品伊人久久久久7777| 国产免费一卡二卡三卡四卡| 在线a毛片免费视频观看| 国产三级精品三级| 少妇脱了内裤让我添| 成 人色 网 站 欧美大片在线观看| 免费视频好湿好紧好大好爽| 午夜精品乱人伦小说区| 亚洲熟妇av乱码在线观看| 国产精品久久自在自线青柠| 久久亚洲精品无码av宋| 被黑人猛躁10次高潮视频| 人妻久久久一区二区三区|