在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. KCTD6 Antibody, HRP conjugated

KCTD6 Antibody, HRP conjugated

  • 中文名稱(chēng)：
    KCTD6兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA822756LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) KCTD6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KCTD6
  • 別名：
    BTB/POZ domain-containing protein KCTD6 antibody; KCASH3 antibody; kctd6 antibody; KCTD6_HUMAN antibody; MGC27385 antibody; potassium channel tetramerization domain containing 6 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human BTB/POZ domain-containing protein KCTD6 protein (1-237AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1; the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation.
  • 基因功能參考文獻(xiàn)：
    1. A biophysical characterization of the POZ/BTB of KCTD6, is reported. PMID: 24307990
    2. Rescuing KCASHs expression reduces the Hedgehog-dependent medulloblastoma growth, suggesting that loss of members of this novel family of native HDAC inhibitors is crucial in sustaining Hh pathway-mediated tumorigenesis. PMID: 21472142
  • 亞細(xì)胞定位：
    Cytoplasm, myofibril, sarcomere, M line.
  • 組織特異性：
    Highly expressed in cerebellum and brain. Expression is down-regulated in medulloblastoma.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 22235

    KEGG: hsa:200845

    STRING: 9606.ENSP00000347188

    UniGene: Hs.13982



主站蜘蛛池模板： 99国产精品欧美一区二区三区| 久久免费视频精品在线| 无码人妻一区二区三区免费n鬼逝| 欧美日本免费一区二区三区| 天天躁夜夜躁狠狠眼泪| 狠狠躁夜夜躁人人爽天天| 少妇被又大又粗猛烈进出视频| 国精产品一区一区三区免费视频| 国产美女极度色诱视频www| 欧美亅性猛交内射| 国产在线观看高清视频黄网| 老熟妇乱子伦牲交视频| 色多多性虎精品无码av| 大桥未久亚洲一区二区| 欧美精品黑人粗大免费| 老熟女重囗味hdxx70星空| 夜爽8888视频在线观看| 天天做天天爱夜夜爽毛片| 亚洲人成人无码网www电影首页| 无码国产69精品久久久孕妇| 国产成人亚洲精品| 好日子在线观看视频大全免费动漫| 中文字幕乱码熟妇五十中出色欲| 深夜福利视频在线播放| 亚洲久久中文字幕www网站| 欧美成人精品三级网站视频| 亚洲中久无码永久在线观看同| 大香伊蕉国产av| 久久婷婷丁香七月色综合| 波多野av一区二区无码| 亚洲 另类 熟女 字幕| 国产a三级久久精品| 成人无码视频在线观看网址| 亚洲视频一区| 国产精品亚洲一区二区三区喷水| 亚洲综合精品成人| 国产精品夜色一区二区三区| 大伊香蕉精品视频在线天堂 | 99九九99九九视频精品| 乱码国产丰满人妻www| 亚洲国产成人一区二区精品区|