在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

KCTD6 Antibody, Biotin conjugated

  • 中文名稱:
    KCTD6兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA822756LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) KCTD6 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    KCTD6
  • 別名:
    BTB/POZ domain-containing protein KCTD6 antibody; KCASH3 antibody; kctd6 antibody; KCTD6_HUMAN antibody; MGC27385 antibody; potassium channel tetramerization domain containing 6 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human BTB/POZ domain-containing protein KCTD6 protein (1-237AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1; the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation.
  • 基因功能參考文獻:
    1. A biophysical characterization of the POZ/BTB of KCTD6, is reported. PMID: 24307990
    2. Rescuing KCASHs expression reduces the Hedgehog-dependent medulloblastoma growth, suggesting that loss of members of this novel family of native HDAC inhibitors is crucial in sustaining Hh pathway-mediated tumorigenesis. PMID: 21472142
  • 亞細胞定位:
    Cytoplasm, myofibril, sarcomere, M line.
  • 組織特異性:
    Highly expressed in cerebellum and brain. Expression is down-regulated in medulloblastoma.
  • 數據庫鏈接:

    HGNC: 22235

    KEGG: hsa:200845

    STRING: 9606.ENSP00000347188

    UniGene: Hs.13982



主站蜘蛛池模板: 国产精品禁忌a片特黄a片| 熟女少妇精品一区二区| 丝袜高跟麻麻浓精受孕人妻| 免费视频国产在线观看| 日韩亚洲欧美精品综合| 又粗又硬又大又爽免费视频播放| 国产在线拍偷自揄拍无码| 久久久www成人免费看片| 天天天狠天天碰天天爱| 国产精品亚洲第一区在线观看| 中文字幕亚洲情99在线| 色一情一乱一伦一视频免费看| 亚洲乱码无人区卡1卡2卡3| 亚洲高清国产拍精品26u| 久久免费看少妇高潮v片特黄| 少妇伦子伦情品无吗| 看黄a大片爽爽影院免费无码| 草草网站影院白丝内射| 国产猛烈高潮尖叫视频免费| 亚洲国产午夜精品理论片在线播放| 国产 | 欧洲野花视频欧洲1| 亚洲嫩模喷白浆在线观看| 国产精品久久久久久久久免费| 69久久精品无码一区二区| 国产精品嫩草影院久久| 护士奶头又大又软又好摸| 无码aⅴ精品一区二区三区| 人妻熟女αⅴ一区二区三区| 亚洲深深色噜噜狠狠爱网站| 99精品视频一区在线观看| 久久久橹橹橹久久久久| 久久久国产打桩机| 国色天香天天影院综合网| 亚洲va中文字幕无码久久不卡 | 欧美另类人妖| 亚洲欧美一区二区三区日产| 天天爽天天摸天天碰| 少妇无码av无码去区钱| 久久丫精品久久丫| 欧美xxxx做受欧美1314| 国产下药迷倒白嫩美女网站|