在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. KCTD6 Antibody, Biotin conjugated

KCTD6 Antibody, Biotin conjugated

  • 中文名稱：
    KCTD6兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA822756LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) KCTD6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KCTD6
  • 別名：
    BTB/POZ domain-containing protein KCTD6 antibody; KCASH3 antibody; kctd6 antibody; KCTD6_HUMAN antibody; MGC27385 antibody; potassium channel tetramerization domain containing 6 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human BTB/POZ domain-containing protein KCTD6 protein (1-237AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1; the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation.
  • 基因功能參考文獻：
    1. A biophysical characterization of the POZ/BTB of KCTD6, is reported. PMID: 24307990
    2. Rescuing KCASHs expression reduces the Hedgehog-dependent medulloblastoma growth, suggesting that loss of members of this novel family of native HDAC inhibitors is crucial in sustaining Hh pathway-mediated tumorigenesis. PMID: 21472142
  • 亞細胞定位：
    Cytoplasm, myofibril, sarcomere, M line.
  • 組織特異性：
    Highly expressed in cerebellum and brain. Expression is down-regulated in medulloblastoma.
  • 數據庫鏈接：

    HGNC: 22235

    KEGG: hsa:200845

    STRING: 9606.ENSP00000347188

    UniGene: Hs.13982



主站蜘蛛池模板： 久久精品国产99久久无毒不卡| 亚洲精品天堂成人片av在线播放 | 精品无码一区二区三区的天堂| 人妻少妇偷人精品视频| 老太婆性杂交视频| 色哟哟在线视频精品一区| 欧洲vat一区二区三区| √天堂资源中文| 国产亚洲综合欧美一区二区| 色五月激情五月| 日韩乱码人妻无码中文字幕久久| 中文字幕人妻被公上司喝醉| 国内精品免费网站牛牛| 人人妻人人澡人人爽不卡视频 | 国产欧美另类久久久精品图片 | 黄页网站在线观看免费视频| 欧美精品中文字幕在线视| 国产精品毛片大码女人| 免费无码va一区二区三区| 色一情一伦一区二区三| 久精品视频在线观看免费| 久久无码av一区二区三区电影网| 女女互磨互喷水高潮les呻吟| 日韩人妻无码一区二区三区久久99| 国产又黄又潮娇喘视频在线观看| 综合自拍亚洲综合图区高清| 狠狠cao日日穞夜夜穞av| 性xxxxx大片免费视频| 内射视频←www夜| 国产成人久久777777| 欧美午夜精品一区二区三区电影| 少妇激情av一区二区三区| 天天影视性色香欲综合网| 熟妇高潮喷沈阳45熟妇高潮喷| 九色九九九老阿姨| 午夜电影网va内射| 69堂人成无码免费视频果冻传媒| 激情综合色五月丁香六月欧美| 手机在线看片| 久久69精品久久久久久hb| 人妻丰满熟妇av无码区app|