在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. KCTD6 Antibody, FITC conjugated

KCTD6 Antibody, FITC conjugated

  • 中文名稱：
    KCTD6兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA822756LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) KCTD6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KCTD6
  • 別名：
    BTB/POZ domain-containing protein KCTD6 antibody; KCASH3 antibody; kctd6 antibody; KCTD6_HUMAN antibody; MGC27385 antibody; potassium channel tetramerization domain containing 6 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human BTB/POZ domain-containing protein KCTD6 protein (1-237AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1; the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation.
  • 基因功能參考文獻：
    1. A biophysical characterization of the POZ/BTB of KCTD6, is reported. PMID: 24307990
    2. Rescuing KCASHs expression reduces the Hedgehog-dependent medulloblastoma growth, suggesting that loss of members of this novel family of native HDAC inhibitors is crucial in sustaining Hh pathway-mediated tumorigenesis. PMID: 21472142
  • 亞細胞定位：
    Cytoplasm, myofibril, sarcomere, M line.
  • 組織特異性：
    Highly expressed in cerebellum and brain. Expression is down-regulated in medulloblastoma.
  • 數據庫鏈接：

    HGNC: 22235

    KEGG: hsa:200845

    STRING: 9606.ENSP00000347188

    UniGene: Hs.13982



主站蜘蛛池模板： 亚洲人成伊人成综合网久久久| 97无码精品综合| 国产欧美日韩久久久久| 久久精品国产网红主播| 亚洲毛片αv无线播放一区 | 国产精品十八禁在线观看| 日本不卡一区二区三区在线| 久草热8精品视频在线观看| 色综合欧美五月俺也去| 久久99国产精品久久| 精精国产xxxx视频在线播放| 精品无码一区二区三区电影| 在线 亚洲 国产 欧美| 国产成人午夜精品影院| 日日夜夜撸啊撸| 欧美xxxx精品另类| 亚洲国产成人久久综合碰| 国产成人欧美日本在线观看| 制服丝袜亚洲中文欧美在线| 国产欧美日韩va另类在线播放| 日日噜噜噜夜夜爽爽狠狠| 免费刺激性视频大片区| 免费人成网站视频在线观看国内| 久久精品超碰av无码| 国产又滑又嫩又白| 日本大片免a费观看视频三区| 国产在线精品无码不卡手机免费 | 午夜理理伦电影a片无码| 国内精品伊人久久久久av| 亚洲精品卡一卡三卡四卡乱码| 国产成人久久av免费| 熟妇的味道hd中文字幕| 国产精品三级国产电影| 国内偷窥一区二区三区视频| 中日韩精品视频在线观看| 摸丰满大乳奶水www免费| 成人午夜高潮刺激免费视频| 最新国产麻豆aⅴ精品无码| 色先锋av资源中文字幕| 免费一本色道久久一区| 日韩免费人妻av无码专区蜜桃|