在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. KCNAB1 Antibody

KCNAB1 Antibody

  • 中文名稱：
    KCNAB1兔多克隆抗體
  • 貨號：
    CSB-PA012013LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Mouse kidney tissue, U87 whole cell lysate, SH-SY5Y whole cell lysate
      All lanes: KCNAB1 antibody at 3.9µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 47, 45, 46 kDa
      Observed band size: 60 kDa
    • IHC image of CSB-PA012013LA01HU diluted at 1:200 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA012013LA01HU diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of HepG2 cells with CSB-PA012013LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) KCNAB1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KCNAB1
  • 別名：
    hKvb3 antibody; hKvBeta3 antibody; K(+) channel subunit beta-1 antibody; KCAB1_HUMAN antibody; KCNA1B antibody; KCNAB1 antibody; Kv-beta-1 antibody; Kvb1.3 antibody; Voltage-gated potassium channel beta-1 subunit antibody; Voltage-gated potassium channel subunit beta-1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Voltage-gated potassium channel subunit beta-1 protein (287-401AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，KCNAB1 Antibody (CSB-PA012013LA01HU)，的標記方式是Non-conjugated。對于KCNAB1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA012013LB01HU KCNAB1 Antibody, HRP conjugated ELISA
    FITC CSB-PA012013LC01HU KCNAB1 Antibody, FITC conjugated
    Biotin CSB-PA012013LD01HU KCNAB1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Modulates action potentials via its effect on the pore-forming alpha subunits. Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity. Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members. Promotes the closure of KCNA1, KCNA2 and KCNA5 channels. Accelerates KCNA4 channel closure. Accelerates the closure of heteromeric channels formed by KCNA1 and KCNA4. Accelerates the closure of heteromeric channels formed by KCNA2, KCNA5 and KCNA6. Isoform KvB1.2 has no effect on KCNA1, KCNA2 or KCNB1. Enhances KCNB1 and KCNB2 channel activity. Binds NADPH; this is required for efficient down-regulation of potassium channel activity. Has NADPH-dependent aldoketoreductase activity. Oxidation of the bound NADPH strongly decreases N-type inactivation of potassium channel activity.
  • 基因功能參考文獻：
    1. Genetic variations of KCNAB1 and CRYAA are associated with age-related nuclear cataract. PMID: 24951543
    2. Protein kinase C inhibition results in a Kv 1.5 and Kv beta 1.3 pharmacology closer to Kv 1.5 channels PMID: 24946104
    3. These results support KCNAB1 as a susceptibility gene for lateral temporal epilepsy , in agreement with previous studies showing that this gene may alter susceptibility to focal epilepsy. PMID: 21333500
    4. Double-mutant cycle analysis indicates that R5 of Kvbeta1.3 interacts with A501 and T480 of Kv1.5, residues located deep within the pore of the channel. PMID: 18987637
  • 亞細胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Shaker potassium channel beta subunit family
  • 組織特異性：
    In brain, expression is most prominent in caudate nucleus, hippocampus and thalamus. Significant expression also detected in amygdala and subthalamic nucleus. Also expressed in both healthy and cardiomyopathic heart. Up to four times more abundant in left
  • 數據庫鏈接：

    HGNC: 6228

    OMIM: 601141

    KEGG: hsa:7881

    STRING: 9606.ENSP00000419952

    UniGene: Hs.654519



主站蜘蛛池模板： 新区乱码无人区二精东| 国产成人精品999在线观看| 韩国精品一区二区无码视频| 亚欧美日韩香蕉在线播放视频| 激情综合激情五月俺也去| 中文字幕乱码亚洲无线码三区| 亚洲不卡1卡2卡三卡入口| 欧美日产国产精品| 午夜熟女插插xx免费视频| 亚洲中文字幕婷婷在线| 亚洲国产精品久久久久4婷婷| 6080亚洲人久久精品| 中文字幕乱码人妻无码久久| 亚洲人成电影在线播放| 亚洲国产精品日韩av不卡在线| 欧美特黄特色三级视频在线观看| 怡红院av亚洲一区二区三区h| а天堂8中文最新版在线官网| 成年免费视频黄网站在线观看| 久久综合狠狠综合久久综| 国产成人青青久久大片| 日本熟妇人妻中出| 国产在线视频精品视频| 三级三级久久三级久久 | 亚洲中文字幕无码永久在线| 国产精品香蕉在线观看| 综合自拍亚洲综合图区欧美| 中文字幕日产乱码国内自| 人妻无码久久一区二区三区免费 | 一区二区国产高清视频在线| 亚洲成av人在线视| 亚洲第一极品精品无码| 韩国三级l中文字幕无码| 国产欧美va天堂在线观看视频下载 | 欧美极品少妇×xxxbbb| 99精品国产一区二区| 国产成人av国语在线观看| 少妇极品熟妇人妻200片| 色偷偷亚洲男人本色 | 国产产品亚洲产品| 少妇下面好紧好多水真爽播放|