在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. KCNAB1 Antibody, Biotin conjugated

KCNAB1 Antibody, Biotin conjugated

  • 中文名稱：
    KCNAB1兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA012013LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) KCNAB1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KCNAB1
  • 別名：
    hKvb3 antibody; hKvBeta3 antibody; K(+) channel subunit beta-1 antibody; KCAB1_HUMAN antibody; KCNA1B antibody; KCNAB1 antibody; Kv-beta-1 antibody; Kvb1.3 antibody; Voltage-gated potassium channel beta-1 subunit antibody; Voltage-gated potassium channel subunit beta-1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Voltage-gated potassium channel subunit beta-1 protein (287-401AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Modulates action potentials via its effect on the pore-forming alpha subunits. Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity. Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members. Promotes the closure of KCNA1, KCNA2 and KCNA5 channels. Accelerates KCNA4 channel closure. Accelerates the closure of heteromeric channels formed by KCNA1 and KCNA4. Accelerates the closure of heteromeric channels formed by KCNA2, KCNA5 and KCNA6. Isoform KvB1.2 has no effect on KCNA1, KCNA2 or KCNB1. Enhances KCNB1 and KCNB2 channel activity. Binds NADPH; this is required for efficient down-regulation of potassium channel activity. Has NADPH-dependent aldoketoreductase activity. Oxidation of the bound NADPH strongly decreases N-type inactivation of potassium channel activity.
  • 基因功能參考文獻：
    1. Genetic variations of KCNAB1 and CRYAA are associated with age-related nuclear cataract. PMID: 24951543
    2. Protein kinase C inhibition results in a Kv 1.5 and Kv beta 1.3 pharmacology closer to Kv 1.5 channels PMID: 24946104
    3. These results support KCNAB1 as a susceptibility gene for lateral temporal epilepsy , in agreement with previous studies showing that this gene may alter susceptibility to focal epilepsy. PMID: 21333500
    4. Double-mutant cycle analysis indicates that R5 of Kvbeta1.3 interacts with A501 and T480 of Kv1.5, residues located deep within the pore of the channel. PMID: 18987637
  • 亞細胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Shaker potassium channel beta subunit family
  • 組織特異性：
    In brain, expression is most prominent in caudate nucleus, hippocampus and thalamus. Significant expression also detected in amygdala and subthalamic nucleus. Also expressed in both healthy and cardiomyopathic heart. Up to four times more abundant in left
  • 數據庫鏈接：

    HGNC: 6228

    OMIM: 601141

    KEGG: hsa:7881

    STRING: 9606.ENSP00000419952

    UniGene: Hs.654519



主站蜘蛛池模板： 天天摸夜夜摸夜夜狠狠添| 亚洲国产精品综合久久网络| 色婷婷久久久swag精品| 久热在线这里只有精品国产| 蜜桃麻豆www久久国产sex| 大肉大捧一进一出好爽视色大师 | 一本一道久久综合狠狠老| 久久精品亚洲日本波多野结衣| 宅男666在线永久免费观看| 国产亚洲综合欧美视频| 麻豆视传媒官网免费观看| 日韩a片无码毛片免费看| 欧美一区内射最近更新| 欧美激情一区二区成人| 麻豆成人av不卡一二三区| 加勒比久久综合网天天| 欧洲熟妇色xxxx欧美老妇老头多毛| 日本人妻中文字幕乱码系列| 狠狠色噜噜狠狠狠狠777米奇小说 又黄又爽的60分钟视频 | 国产成人美女视频网站| 一本加勒比hezyo无码人妻| 国产手机在线精品| 免费精品国偷自产在线在线| 天天躁夜夜躁狠狠综合2020| 国产猛烈高潮尖叫视频免费| 亚洲国产精品久久亚洲精品| 一本色道久久东京热| 精品人妻无码区二区三区| 国产精品18久久久久久vr| 国产拍拍拍无码视频免费| 日本少妇xxx做受| 国产公开免费人成视频| 狠狠综合久久久久尤物丿| 成年午夜精品久久久精品| 成人无码一区二区三区网站 | 麻豆av一区二区天美传媒| 亚洲aⅴ在线无码天堂777| 久久精品青青草原伊人| 99香蕉国产精品偷在线观看| 日韩丝袜欧美人妻制服| 久久精品国产只有精品2020|