在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

KCNAB1 Antibody, Biotin conjugated

  • 中文名稱:
    KCNAB1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA012013LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) KCNAB1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    KCNAB1
  • 別名:
    hKvb3 antibody; hKvBeta3 antibody; K(+) channel subunit beta-1 antibody; KCAB1_HUMAN antibody; KCNA1B antibody; KCNAB1 antibody; Kv-beta-1 antibody; Kvb1.3 antibody; Voltage-gated potassium channel beta-1 subunit antibody; Voltage-gated potassium channel subunit beta-1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Voltage-gated potassium channel subunit beta-1 protein (287-401AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Modulates action potentials via its effect on the pore-forming alpha subunits. Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity. Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members. Promotes the closure of KCNA1, KCNA2 and KCNA5 channels. Accelerates KCNA4 channel closure. Accelerates the closure of heteromeric channels formed by KCNA1 and KCNA4. Accelerates the closure of heteromeric channels formed by KCNA2, KCNA5 and KCNA6. Isoform KvB1.2 has no effect on KCNA1, KCNA2 or KCNB1. Enhances KCNB1 and KCNB2 channel activity. Binds NADPH; this is required for efficient down-regulation of potassium channel activity. Has NADPH-dependent aldoketoreductase activity. Oxidation of the bound NADPH strongly decreases N-type inactivation of potassium channel activity.
  • 基因功能參考文獻:
    1. Genetic variations of KCNAB1 and CRYAA are associated with age-related nuclear cataract. PMID: 24951543
    2. Protein kinase C inhibition results in a Kv 1.5 and Kv beta 1.3 pharmacology closer to Kv 1.5 channels PMID: 24946104
    3. These results support KCNAB1 as a susceptibility gene for lateral temporal epilepsy , in agreement with previous studies showing that this gene may alter susceptibility to focal epilepsy. PMID: 21333500
    4. Double-mutant cycle analysis indicates that R5 of Kvbeta1.3 interacts with A501 and T480 of Kv1.5, residues located deep within the pore of the channel. PMID: 18987637
  • 亞細胞定位:
    Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Shaker potassium channel beta subunit family
  • 組織特異性:
    In brain, expression is most prominent in caudate nucleus, hippocampus and thalamus. Significant expression also detected in amygdala and subthalamic nucleus. Also expressed in both healthy and cardiomyopathic heart. Up to four times more abundant in left
  • 數據庫鏈接:

    HGNC: 6228

    OMIM: 601141

    KEGG: hsa:7881

    STRING: 9606.ENSP00000419952

    UniGene: Hs.654519



主站蜘蛛池模板: 国产精品美女久久久浪潮av| 国产午夜精品无码一区二区| 精品无人区无码乱码毛片国产| 国产成a人亚洲精品无码樱花| 超碰曰口干天天种夜夜爽| 中文字字幕乱码视频高清| 国产成人无码精品亚洲| 丁香五香天堂网| 国产免费看又黄又大又污的胸 | av无码精品一区二区三区四区| 久久久久无码国产精品不卡| 男女真人国产牲交a做片野外| 特级小箩利无码毛片| 国产精品乱码高清在线观看| 亚洲精品第一国产综合野草社区 | 亚洲欧美国产免费综合视频| 人人妻人人澡人人爽欧美二区| 国产综合色产在线精品| 日韩精品一区二区av在线| 人妻无码一区二区三区tv| 欧美一区二区三区激情| 男女免费观看做爰视频在线观看| 国产精品三级av及在线观看| 97se色综合一区二区二区| 欧美激情精品久久| 狠狠爱亚洲五月婷婷av| 18禁无遮挡羞羞污污污污网站| 无码少妇一区二区性色av| 风流老熟女一区二区三区| 337p粉嫩日本欧洲亚福利| 高潮迭起av乳颜射后入| 毛片免费视频肛交颜射免费视频 | 久久亚洲日韩精品一区二区三区| 无码人妻一区二区三区免费看成人| 色综合色狠狠天天综合色 | 韩国三级hd中文字幕| 成年女人看片永久免费视频| 国产熟人av一二三区| 粗大挺进尤物人妻中文字幕| 在线天堂资源www在线污| 性做久久久久久久免费看|