在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

KCNAB1 Antibody, FITC conjugated

  • 中文名稱:
    KCNAB1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA012013LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) KCNAB1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    KCNAB1
  • 別名:
    hKvb3 antibody; hKvBeta3 antibody; K(+) channel subunit beta-1 antibody; KCAB1_HUMAN antibody; KCNA1B antibody; KCNAB1 antibody; Kv-beta-1 antibody; Kvb1.3 antibody; Voltage-gated potassium channel beta-1 subunit antibody; Voltage-gated potassium channel subunit beta-1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Voltage-gated potassium channel subunit beta-1 protein (287-401AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Modulates action potentials via its effect on the pore-forming alpha subunits. Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity. Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members. Promotes the closure of KCNA1, KCNA2 and KCNA5 channels. Accelerates KCNA4 channel closure. Accelerates the closure of heteromeric channels formed by KCNA1 and KCNA4. Accelerates the closure of heteromeric channels formed by KCNA2, KCNA5 and KCNA6. Isoform KvB1.2 has no effect on KCNA1, KCNA2 or KCNB1. Enhances KCNB1 and KCNB2 channel activity. Binds NADPH; this is required for efficient down-regulation of potassium channel activity. Has NADPH-dependent aldoketoreductase activity. Oxidation of the bound NADPH strongly decreases N-type inactivation of potassium channel activity.
  • 基因功能參考文獻:
    1. Genetic variations of KCNAB1 and CRYAA are associated with age-related nuclear cataract. PMID: 24951543
    2. Protein kinase C inhibition results in a Kv 1.5 and Kv beta 1.3 pharmacology closer to Kv 1.5 channels PMID: 24946104
    3. These results support KCNAB1 as a susceptibility gene for lateral temporal epilepsy , in agreement with previous studies showing that this gene may alter susceptibility to focal epilepsy. PMID: 21333500
    4. Double-mutant cycle analysis indicates that R5 of Kvbeta1.3 interacts with A501 and T480 of Kv1.5, residues located deep within the pore of the channel. PMID: 18987637
  • 亞細胞定位:
    Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Shaker potassium channel beta subunit family
  • 組織特異性:
    In brain, expression is most prominent in caudate nucleus, hippocampus and thalamus. Significant expression also detected in amygdala and subthalamic nucleus. Also expressed in both healthy and cardiomyopathic heart. Up to four times more abundant in left
  • 數據庫鏈接:

    HGNC: 6228

    OMIM: 601141

    KEGG: hsa:7881

    STRING: 9606.ENSP00000419952

    UniGene: Hs.654519



主站蜘蛛池模板: 亚洲日韩欧美一区二区三区在线| 久久99精品久久只有精品| 99精品偷自拍| 国产欧美二区综合| 亚洲va天堂va欧美片a在线| 最新无码人妻在线不卡| 久久一日本综合色鬼综合色| 久久久噜噜噜久久| 国产在线精品一区二区| 国产精品一国产精品一k频道| 成人无码视频在线观看网址| 久久国产免费直播| 亚洲综合一区二区三区无码 | 久久久久99精品成人片| 极品少妇被啪到呻吟喷水| 白丝美女被狂躁免费视频网站| 18禁无遮挡羞羞啪啪免费网站| 欧美亚洲国产片在线播放| 国产网友自拍在线视频| 亚洲在av人极品无码| 免费不卡无码av在线观看| 精品国产污污免费网站入口| 国产欧美另类久久精品蜜芽| 天天做av天天爱天天爽| 国产精品偷伦视频观看免费| 亚洲欧美乱日韩乱国产| 高h猛烈失禁潮喷无码视频| 无码综合天天久久综合网| 精品999日本久久久影院| 最新日韩精品中文字幕| 久久久精品人妻一区亚美研究所| 在线 亚洲 国产 欧美| 国产免费不卡av在线播放| 偷偷色噜狠狠狠狠的777米奇| 午夜时刻免费入口| 无码少妇高潮浪潮av久久| 欧美熟妇色ⅹxxx欧美妇| 欧美乱妇狂野欧美在线视频| 国产精品内射视频免费| 亚洲精品中文字幕一区二区三区| 国产精品av免费观看|