在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. KCNAB1 Antibody, FITC conjugated

KCNAB1 Antibody, FITC conjugated

  • 中文名稱：
    KCNAB1兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA012013LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) KCNAB1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KCNAB1
  • 別名：
    hKvb3 antibody; hKvBeta3 antibody; K(+) channel subunit beta-1 antibody; KCAB1_HUMAN antibody; KCNA1B antibody; KCNAB1 antibody; Kv-beta-1 antibody; Kvb1.3 antibody; Voltage-gated potassium channel beta-1 subunit antibody; Voltage-gated potassium channel subunit beta-1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Voltage-gated potassium channel subunit beta-1 protein (287-401AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Modulates action potentials via its effect on the pore-forming alpha subunits. Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity. Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members. Promotes the closure of KCNA1, KCNA2 and KCNA5 channels. Accelerates KCNA4 channel closure. Accelerates the closure of heteromeric channels formed by KCNA1 and KCNA4. Accelerates the closure of heteromeric channels formed by KCNA2, KCNA5 and KCNA6. Isoform KvB1.2 has no effect on KCNA1, KCNA2 or KCNB1. Enhances KCNB1 and KCNB2 channel activity. Binds NADPH; this is required for efficient down-regulation of potassium channel activity. Has NADPH-dependent aldoketoreductase activity. Oxidation of the bound NADPH strongly decreases N-type inactivation of potassium channel activity.
  • 基因功能參考文獻：
    1. Genetic variations of KCNAB1 and CRYAA are associated with age-related nuclear cataract. PMID: 24951543
    2. Protein kinase C inhibition results in a Kv 1.5 and Kv beta 1.3 pharmacology closer to Kv 1.5 channels PMID: 24946104
    3. These results support KCNAB1 as a susceptibility gene for lateral temporal epilepsy , in agreement with previous studies showing that this gene may alter susceptibility to focal epilepsy. PMID: 21333500
    4. Double-mutant cycle analysis indicates that R5 of Kvbeta1.3 interacts with A501 and T480 of Kv1.5, residues located deep within the pore of the channel. PMID: 18987637
  • 亞細胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Shaker potassium channel beta subunit family
  • 組織特異性：
    In brain, expression is most prominent in caudate nucleus, hippocampus and thalamus. Significant expression also detected in amygdala and subthalamic nucleus. Also expressed in both healthy and cardiomyopathic heart. Up to four times more abundant in left
  • 數據庫鏈接：

    HGNC: 6228

    OMIM: 601141

    KEGG: hsa:7881

    STRING: 9606.ENSP00000419952

    UniGene: Hs.654519



主站蜘蛛池模板： 里番本子纯肉侵犯肉全彩无码| 国产成人无码va在线观看| 神马午夜福利不卡片在线| 欧美亚洲国产第一精品久久| 狠狠色噜噜狠狠狠狠色综合网| 大伊香蕉精品视频在线| 精品午夜福利无人区乱码一区| 成人内射国产免费观看| 成人亚洲欧美在线观看| 看国产一毛片在线看手机看| 国产精品区一区二区三在线播放| 欧美亚洲国产片在线播放| 成人精品视频99在线观看免费| 全球av集中精品导航福利| 欧美老妇bbbwwbbbww| 亚洲一卡2卡3卡4卡5卡精品| 四虎永久在线精品免费网站 | 无码人妻丰满熟妇区毛片| 野外少妇被弄到喷水在线观看 | 国内精品自在自线视频| 大黑人交xxxx18视频| 日韩综合夜夜香内射| 青草伊人久久综在合线亚洲观看| 亚洲色偷偷偷网站色偷一区 | 久久久噜噜噜www成人网| 老太脱裤让老头玩ⅹxxxx| 日韩中文高清在线专区| 天天av天天av天天透| 久久婷婷成人综合色综合| 精品免费久久久久久久| 亚洲精品国产福利一区二区| 隔壁人妻被水电工征服| 最近2019免费中文第一页| 国偷自产一区二区免费视频| 亚洲综合最新无码专区| 麻豆成人av不卡一二三区| 国产精品久久久久aaaa| 50岁退休熟女露脸高潮| 色综合久久久久综合99| 狠狠色丁香久久婷婷综合蜜芽五月 | 玩弄人妻少妇500系列|