在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ITGA11 Antibody

  • 中文名稱:
    ITGA11兔多克隆抗體
  • 貨號:
    CSB-PA891732ESR1HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA891732ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA891732ESR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ITGA11 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    integrin a11 antibody; Integrin alpha 11 antibody; Integrin alpha-11 antibody; ITA11_HUMAN antibody; ITGA11 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Integrin alpha-11 protein (940-1141AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Integrin alpha-11/beta-1 is a receptor for collagen.
  • 基因功能參考文獻:
    1. ITGA11 is a highly promising target that is selectively overexpressed in myofibroblasts during fibrotic diseases and regulates myofibroblast differentiation and key phenotypic characteristics. PMID: 29147013
    2. By employing co-immunoprecipitation and confocal microscopy analysis we showed that integrin alpha11beta1 and protein disulfide isomerase (PDI) create complexes bounded by disulfide bonds. Using surface plasmon resonance we provide biochemical evidence that PDI can interact directly with integrin subunit alpha11. PMID: 29203246
    3. Using MDR and RF, the overall best classifier of lung cancer status were SNPs rs1799732 (DRD2), rs5744256 (IL-18), rs2306022 (ITGA11) with training accuracy of 0.6592 and a testing accuracy of 0.6572 and a cross-validation consistency of 10/10 with permutation testing P<0.0001 PMID: 27121382
    4. FGF2 may be redirecting fibroblasts towards an anti-fibrotic phenotype during wound healing by overriding TGFb1 mediated ITGA11 expression. PMID: 26403263
    5. glycated collagen in the cardiac interstitium triggers an autocrine TGF-beta2 signaling pathway that stimulates alpha11 integrin expression through Smad2/3 binding elements in the alpha11 integrin promoter PMID: 24962729
    6. Myometrium and uterine fibroids express ITGA11. PMID: 24520080
    7. Interactions between alpha11 integrins and the Smad-dependent TGF-beta2 signalling may contribute to the formation of pro-fibrotic myofibroblasts and the development of a fibrotic interstitium in diabetic cardiomyopathy. PMID: 22869616
    8. The disturbance of alpha11beta1 mediated interactions to collagen I results in a tremendous reduction of hMSC numbers owing to mitochondrial leakage accompanied by Bcl-2-associated X protein upregulation. PMID: 21796158
    9. Data show that the 3 kb alpha11 promoter contains most of the regulatory elements that direct ectomesenchymal and mesodermal fibroblast-specific expression. PMID: 19913614
    10. Major transcription start site mapped. A core promoter [nt (-)127-(+)25], a potential silencer region [nt (-)400-(-)127] and a potential enhancer region [nt (-)1519-(-)400] identified as important for alpha11 transcription in mesenchymal cells. PMID: 12392762
    11. the GFOGER sequence in fibrillar collagens is a common recognition motif used by integrins, particularly alpha11beta1 PMID: 12496264
    12. A new interferon stimulated gene. (Integrin alpha 11) PMID: 16697656
    13. Through interaction between matrix collagen and stromal fibroblasts, integrin alpha 11 stimulates cancer cell growth. PMID: 17600088
    14. analysis of a prokaryotic Scl1 collagen sequence motif that mediates binding to human collagen receptors, integrins alpha2beta1 and alpha11beta1 PMID: 18990704
    15. is a major collagen receptor on human periodontal ligament cells [and plays] a role in collagen lattice remodeling [ITGA11B1] PMID: 19641149

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Integrin alpha chain family
  • 組織特異性:
    According to PubMed:10464311, highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. According to PubMed:10486209, also found in brain, colon, lung, small i
  • 數據庫鏈接:

    HGNC: 6136

    OMIM: 604789

    KEGG: hsa:22801

    STRING: 9606.ENSP00000327290

    UniGene: Hs.436416



主站蜘蛛池模板: 无码137片内射在线影院| 看曰本女人大战黑人视频| 日本www网站色情乱码| 色综合欧美亚洲国产| 麻豆国产一区二区三区四区| 国产三级视频在线播放线观看| 国产做爰xxxⅹ高潮视频12p| 强奷人妻日本中文字幕| 国内揄拍国内精品少妇 | 亚洲色成人网一二三区| 国产萌白酱喷水视频在线观看| 成 人 a v免费视频在线观看| 麻豆亚洲国产成人精品无码区| 欧美日本国产va高清cabal| 亚洲精品中国国产嫩草影院美女| 中文字幕乱码一区二区免费| 久久亚洲精品高潮综合色a片| 久碰久摸久看视频在线观看| 免费拍拍拍网站| 亚洲精品少妇高清30p| 最新系列国产专区|亚洲国产| 国产精品美女久久久久久久| 韩国三级中文字幕hd| 蜜臀av片在线观看| 菠萝菠萝蜜午夜视频在线播放观看| 7878成人国产在线观看| 国产成人精品日本亚洲77上位| 日本少妇毛茸茸高潮| 精品精品国产高清a毛片| 亚洲欧美国产制服图片区| 免费va人成视频网站全| 国产成人综合在线女婷五月99播放 | 日韩精品成人一区二区三区| 欧美阿v高清资源在线| 色老头精品午夜福利视频| 国产片精品av在线观看夜色| 国产探花在线精品一区二区| 一二三四免费观看在线视频中文版| 国产精品国产高清国产av| 日本边添边摸边做边爱| 欧美做受又硬又粗又大视频|