在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. IQGAP2 Antibody, HRP conjugated

IQGAP2 Antibody, HRP conjugated

  • 中文名稱：
    IQGAP2兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA615701LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) IQGAP2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    IQ motif containing GTPase activating protein 2 antibody; IQGA2_HUMAN antibody; Iqgap2 antibody; Ras GTPase activating-like protein antibody; Ras GTPase-activating-like protein IQGAP2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Ras GTPase-activating-like protein IQGAP2 protein (1245-1395AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.
  • 基因功能參考文獻(xiàn)：
    1. IQGAP2 expression correlated positively with survivability, on the contrary, IQGAP3 expression levels correlated inversely with survivability PMID: 29073199
    2. The structural basis for Cdc42-induced dimerization of IQGAP1 and IQGAP2 has been uncovered. PMID: 27524202
    3. The most frequently identified and connected to preterm birth genes in the exome library were IGF1, ATM and IQGAP2. PMID: 27163930
    4. IQGAP2 TagSNP rs457717 (A/G) was not associated with Age-Related Hearing impairment in Han male Chinese population. PMID: 26187738
    5. Thus, these data identified IQGAP2 as a novel tumor suppressor for ovarian cancer to inhibit cell invasion through regulating Wnt/b-catenin signaling, and provided a new biomarker and potential therapeutic strategy for this disease. PMID: 26549344
    6. we identified IQGAP2 as a human and zebrafish podocyte gene product that is downregulated in microarray data sets from kidney biopsies of human patients with focal segmental glomerulosclerosis and minimal change nephrotic syndrome. PMID: 26154927
    7. Data show that IQ motif-containing GTPase-activating protein 2 (IQGAP2) expression is altered in colitis. PMID: 26047140
    8. IQGAP1, IQGAP2, and IQGAP3 have diverse roles in vertebrate physiology, operating in the kidney, nervous system, cardiovascular system, pancreas, and lung. (Review) PMID: 25722290
    9. Mammalian IQGAP proteins may play a role in cytokinesis by regulating the localization of key cytokinesis regulatory proteins to the contractile apparatus during mitosis. PMID: 25229330
    10. Low IQGAP2 expression was associated with hepatocellular carcinoma. PMID: 24998570
    11. The first IQ-motifs from IQGAP2 and IQGAP3 form transient interactions with calmodulin in the absence of calcium. PMID: 21299499
    12. observations strongly indicate that IQGAP2 is a surveillance type of tumour suppressor for prostate cancer PMID: 22406297
    13. increased IQGAP1 and/or decreased IQGAP2 contribute to the pathogenesis of human HCC. PMID: 20977743
    14. The top-ranked SNP, rs457717 for association with age-related hearing impairment(P-value 3.55 x 10(-7)), was localised in an intron of the IQ motif-containing GTPase-activating-like protein (IQGAP2). PMID: 20068591
    15. The gene for the putative rac1/cdc42 effector protein IQGAP2 was found in the PAR gene cluster at 5q13, flanked by PAR1 & encompassing PAR3. It functions as a GTP-dependent effector protein in thrombin-induced platelet cytoskeletal reorganization. PMID: 12515716
    16. silencing of IQGAP2 by promoter methylation may contribute to gastric cancer development. PMID: 17957782

    顯示更多

    收起更多

  • 組織特異性：
    Isoform 2 expression is enhanced in testis.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 6111

    OMIM: 605401

    KEGG: hsa:10788

    STRING: 9606.ENSP00000274364

    UniGene: Hs.291030



主站蜘蛛池模板： 国内久久婷婷六月综合欲色啪| 特黄做受又粗又长又大又硬| 狠狠色狠狠色五月激情| 亚洲色欲色欲www在线看| 一区二区三区在线 | 欧洲| 国产精品无码制服丝袜| 色综合av综合无码综合网站| 香港特级三a毛片免费观看| av大片在线无码免费| 波多野结衣乳巨码无在线观看| 深夜福利啪啪片| 人妻系列无码专区喂奶| 亚洲日本va中文字幕亚洲| 亚洲色婷婷一区二区三区| 少妇高潮流白浆在线观看| 六月丁香亚洲综合在线视频| 99偷拍视频精品一区二区| 中文字幕无码一区二区免费| 亚洲欧美日韩中文加勒比| 日韩精品一卡2卡3卡4卡新区视频| 亚洲情综合五月天| 国产精品国色综合久久| 日韩人妻无码免费视频一二区| 日本又黄又爽又色又刺激的视频| 成人做受黄大片| 精品国产一区二区三区四区在线看| 色777狠狠狠综合| 国产偷国产偷亚洲高清app| 啦啦啦www在线观看免费视频 | 国产精品香港三级国产av| 狠狠色噜噜狠狠狠7777米奇| 少妇富婆高级按摩出水高潮| 久久免费的精品国产v∧| 天天爱天天做天天做天天吃中文 | a三级三级成人网站在线视频| 无码中文字幕在线播放2| 久久综合伊人九色综合| 久久综合九色综合欧洲98| 无套内谢的新婚少妇国语播放| 狠狠色噜噜狼狼狼色综合久| 成人av片在线观看免费|