在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

IL13RA1 Antibody, Biotin conjugated

  • 中文名稱:
    IL13RA1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA011591LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) IL13RA1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    IL13RA1; IL13R; IL13RA; Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19; CD antigen CD213a1
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Interleukin-13 receptor subunit alpha-1 protein (22-234AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
  • 基因功能參考文獻:
    1. High IL13RA1 expression is associated with Invasive breast Cancer. PMID: 28634667
    2. in humans and mice indicate, for the first time, a role of interleukin-13 receptor alpha1 in myocardial homeostasis and heart failure and suggests a new therapeutic target to treat heart disease. PMID: 28528324
    3. sIL13ralpha1 as a circulating human protein with an unexpected role in glucose metabolism. PMID: 28874358
    4. IL-13Ralpha1 has a protective role in bleomycin-induced pulmonary injury and repair. PMID: 26153764
    5. required for induction of the alternative macrophage activation pathway by IL-13 but not by IL-4 PMID: 25766112
    6. Results identified FAM120A in the IL13/IL13Ralpha2 signaling pathway as a key mediator of invasion and liver metastasis in colon cancer. PMID: 25896327
    7. miR-143 regulation of IL-13-induced inflammatory cytokine and mucus production in nasal epithelial cells from allergic rhinitis patients probably partly depends on inhibition of IL13Ralpha1. PMID: 25529447
    8. MiR-143 may be associated with allergic reaction in human mast cells via downregulation of IL13RA1. PMID: 23965966
    9. In humans, IL-13Ralpha1 lies within the PARK12 locus of susceptibility to Parkinson's disease and may have a role in the pathogenesis of this neurodegenerative disease. PMID: 23169588
    10. These results indicate that an inherited polymorphism of the IL-4R controls the ability of the human immune system to regulate the magnitude of IL-17 production PMID: 21294892
    11. The IL-13R A(1) +1398 A/G polymorphism does not contribute to asthma or allergic rhinitis susceptibility. PMID: 21425907
    12. IL-13Ralpha1 is expressed on human CD4(+) T(H)17 cells PMID: 21236478
    13. Mutation and functional analysis in human malignant glioma cells PMID: 11939409
    14. IL4RA and STAT6 are candidate genes for atopic disorders. 26 single-nucleotide polymorphisms (SNPs)and simple repeats are being reported spanning a total of 147kb in IL4RA and STAT6 genes of the Indian population PMID: 12522691
    15. Allele frequency of IL13RA1 polymorphism was not associated with rapid decline of lung function in smokers. PMID: 12594065
    16. Overexpression of IL-13Ralpha1 may play some role in pathogenesis of chronic stage of atopic dermatitis or psoriasis. PMID: 14527737
    17. Bronchial submucosal mast cell IL-13 receptor alpha 1 expression is higher in asthmatics than normal controls. PMID: 16918506
    18. IL-13Ralpha1 polymorphism was associated with higher total IgE in children with atopic asthma PMID: 17006604
    19. the IL13RA1 subunit gene -281T>G and 1365A>G polymorphisms do not contribute to asthma susceptibility or severity, although the IL13RA1 subunit gene locus might be involved in the control of immunoglobulin E production PMID: 17392323
    20. concomitant expression of IL-13Ralpha1 and IL-13Ralpha2 may be associated with the pathogenesis of idiopathic interstitial pneumonia. PMID: 19654941

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Type I cytokine receptor family, Type 5 subfamily
  • 組織特異性:
    Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.
  • 數據庫鏈接:

    HGNC: 5974

    OMIM: 300119

    KEGG: hsa:3597

    STRING: 9606.ENSP00000360730

    UniGene: Hs.496646



主站蜘蛛池模板: 亚洲人成无码网www动漫| 亚洲国产精彩中文乱码av| 国产精品白丝久久av网站| 在线看片免费人成视频国产片| 激情综合色五月六月婷婷| 国产综合18久久久久久| 亚洲午夜久久久久妓女影院| 毛片免费全部播放无码| 中文字幕美人妻亅u乚一596| 国产日韩欧美亚欧在线| 无遮挡激情视频国产在线观看 | 国产经典三级av在线播放| 亚洲欧美日韩综合久久久久久| 国产网红无码精品视频| 亚洲色播爱爱爱爱爱爱爱| 久久www成人看片免费不卡| 一区二三区在线 | 中国| 亚洲性夜色噜噜噜网站2258kk| 精品国产欧美一区二区| 女人被黑人躁得好爽视频| 亚洲精品成人福利网站| 香蕉久久人人97超碰caoproen| 成人性做爰aaa片免费看不忠| 好男人社区神马在线观看www| 欧美日韩精品suv| 人摸人人人澡人人超碰97| 少妇激情一区二区三区视频| 隔壁邻居是巨爆乳寡妇| 久久久受www免费人成| 国产在线乱码一区二区三区| 他掀开裙子把舌头伸进去添视频| 偷偷色噜狠狠狠狠的777米奇| 国产精品无码免费专区午夜| 一区二区无码免费视频网站| 亚洲桃色天堂网| 国产偷窥熟妇高潮呻吟| 成人免费的视频| 五月丁香综合缴情六月小说| 无码人妻少妇精品无码专区漫画| 男女无遮挡激情视频| 国产精品186在线观看在线播放|