在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Interleukin-13 receptor subunit alpha-1 (IL13RA1), partial

Recombinant Human Interleukin-13 receptor subunit alpha-1 (IL13RA1), partial

  • 中文名稱：
    人IL13RA1重組蛋白
  • 貨號：
    CSB-YP011591HU1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人IL13RA1重組蛋白
  • 貨號：
    CSB-EP011591HU1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人IL13RA1重組蛋白
  • 貨號：
    CSB-EP011591HU1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人IL13RA1重組蛋白
  • 貨號：
    CSB-BP011591HU1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人IL13RA1重組蛋白
  • 貨號：
    CSB-MP011591HU1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    IL13RA1; IL13R; IL13RA; Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19; CD antigen CD213a1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
  • 基因功能參考文獻：
    1. High IL13RA1 expression is associated with Invasive breast Cancer. PMID: 28634667
    2. in humans and mice indicate, for the first time, a role of interleukin-13 receptor alpha1 in myocardial homeostasis and heart failure and suggests a new therapeutic target to treat heart disease. PMID: 28528324
    3. sIL13ralpha1 as a circulating human protein with an unexpected role in glucose metabolism. PMID: 28874358
    4. IL-13Ralpha1 has a protective role in bleomycin-induced pulmonary injury and repair. PMID: 26153764
    5. required for induction of the alternative macrophage activation pathway by IL-13 but not by IL-4 PMID: 25766112
    6. Results identified FAM120A in the IL13/IL13Ralpha2 signaling pathway as a key mediator of invasion and liver metastasis in colon cancer. PMID: 25896327
    7. miR-143 regulation of IL-13-induced inflammatory cytokine and mucus production in nasal epithelial cells from allergic rhinitis patients probably partly depends on inhibition of IL13Ralpha1. PMID: 25529447
    8. MiR-143 may be associated with allergic reaction in human mast cells via downregulation of IL13RA1. PMID: 23965966
    9. In humans, IL-13Ralpha1 lies within the PARK12 locus of susceptibility to Parkinson's disease and may have a role in the pathogenesis of this neurodegenerative disease. PMID: 23169588
    10. These results indicate that an inherited polymorphism of the IL-4R controls the ability of the human immune system to regulate the magnitude of IL-17 production PMID: 21294892
    11. The IL-13R A(1) +1398 A/G polymorphism does not contribute to asthma or allergic rhinitis susceptibility. PMID: 21425907
    12. IL-13Ralpha1 is expressed on human CD4(+) T(H)17 cells PMID: 21236478
    13. Mutation and functional analysis in human malignant glioma cells PMID: 11939409
    14. IL4RA and STAT6 are candidate genes for atopic disorders. 26 single-nucleotide polymorphisms (SNPs)and simple repeats are being reported spanning a total of 147kb in IL4RA and STAT6 genes of the Indian population PMID: 12522691
    15. Allele frequency of IL13RA1 polymorphism was not associated with rapid decline of lung function in smokers. PMID: 12594065
    16. Overexpression of IL-13Ralpha1 may play some role in pathogenesis of chronic stage of atopic dermatitis or psoriasis. PMID: 14527737
    17. Bronchial submucosal mast cell IL-13 receptor alpha 1 expression is higher in asthmatics than normal controls. PMID: 16918506
    18. IL-13Ralpha1 polymorphism was associated with higher total IgE in children with atopic asthma PMID: 17006604
    19. the IL13RA1 subunit gene -281T>G and 1365A>G polymorphisms do not contribute to asthma susceptibility or severity, although the IL13RA1 subunit gene locus might be involved in the control of immunoglobulin E production PMID: 17392323
    20. concomitant expression of IL-13Ralpha1 and IL-13Ralpha2 may be associated with the pathogenesis of idiopathic interstitial pneumonia. PMID: 19654941

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Type I cytokine receptor family, Type 5 subfamily
  • 組織特異性：
    Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.
  • 數據庫鏈接：

    HGNC: 5974

    OMIM: 300119

    KEGG: hsa:3597

    STRING: 9606.ENSP00000360730

    UniGene: Hs.496646



主站蜘蛛池模板： 人妻影音先锋啪啪av资源| 2020无码专区人妻系列日韩| 1000部精品久久久久久久久| 亚洲午夜理论片在线观看 | 国产一区二区在线视频| 国产精品综合一区二区三区| 羞涩的丰满人妻40p| 精品人妻av区波多野结衣| 中文字幕在线日亚州9| 亚洲熟女乱综合一区二区在线 | 亚洲无日韩码精品| 亚洲愉拍自拍另类天堂| 免费三级网站| 琪琪女色窝窝777777| 国产精品美女久久久网站动漫| 越南女子杂交内射bbwxz| 久久偷看各类wc女厕嘘嘘偷窃| 亚洲日本中文字幕天天更新 | 东北老女人高潮大喊舒服死了| 性欧美丰满熟妇xxxx性| 97se亚洲精品一区| 国内揄拍国内精品对白86| 久久―日本道色综合久久| 曰批免费视频播放免费| 国产精品日韩av在线播放| 亚洲 日本 欧美 中文字幕| 在线播放国产麻豆va剧情| 中文天堂网www新版资源在线| 无码熟妇人妻av在线电影| 女人高潮流白浆视频| 色综合色狠狠天天综合网| 久久精品av国产一区二区| 性欧美大战久久久久久久久| 中文幕无线码中文字夫妻| 色欲av久久综合人妻无码| 18无码粉嫩小泬无套在线观看| 国产精品99久久免费黑人人妻 | 日韩综合夜夜香内射| 奇米综合四色77777久久| 国产午夜鲁丝片av无码| 色先锋av资源中文字幕|