在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HOXA4 Antibody

HOXA4 Antibody

  • 中文名稱：
    HOXA4兔多克隆抗體
  • 貨號：
    CSB-PA010654LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Rat kidney tissue
      All lanes: HOXA4 antibody at 2.3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 35 kDa
      Observed band size: 35 kDa
    • IHC image of CSB-PA010654LA01HU diluted at 1:800 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HOXA4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HOXA4
  • 別名：
    Dfd like protein antibody; Homeo box A4 antibody; Homeobox A4 antibody; Homeobox protein Hox-1.4 antibody; Homeobox protein Hox-1D antibody; Homeobox protein Hox-A4 antibody; Hox 1.4 like protein antibody; hox-1.4 antibody; hox-1d antibody; HOX1 antibody; HOX1D antibody; HOXA4 antibody; HXA4_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Rat
  • 免疫原：
    Recombinant Human Homeobox protein Hox-A4 protein (23-173AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，HOXA4 Antibody (CSB-PA010654LA01HU)，的標記方式是Non-conjugated。對于HOXA4 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應用
    HRP CSB-PA010654LB01HU HOXA4 Antibody, HRP conjugated ELISA
    FITC CSB-PA010654LC01HU HOXA4 Antibody, FITC conjugated
    Biotin CSB-PA010654LD01HU HOXA4 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:500-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to sites in the 5'-flanking sequence of its coding region with various affinities. The consensus sequences of the high and low affinity binding sites are 5'-TAATGA[CG]-3' and 5'-CTAATTTT-3'.
  • 基因功能參考文獻：
    1. HOXA4/HOXB3 gene expression-based risk score may be useful for prognostic risk stratification and warrants prospective validation in HGSOC patients. PMID: 29402501
    2. Overexpression of HOXA4 and HOXA9 contributes to self-renewal and overpopulation of stem cells in colorectal cancers. PMID: 28464221
    3. HOXA4 increases short-term repopulation to higher levels than HOXB4, which may involve Notch signaling to induce self-renewal of primitive hematopoietic cells PMID: 26166023
    4. The NK AML patients with NPM1 mutations exhibited elevated HOXA4 methylation and expression levels of HOXA5 and MEIS1 compared with the NPM1 wildtype patients. PMID: 25585874
    5. promoter hypermethylation of HOXA4 gene could be an epigenetic mechanism mediating IM resistance in CML patients. PMID: 23484077
    6. HOXA4 showed nuclear & perinuclear staining in endothelial & smooth muscle cells in aorta. Spatial variation in expression in human aortas persisted into adulthood. Downregulation of HOXA4 expression was associated with abdominal aortic aneurysm. PMID: 21627813
    7. Studies suggest that HOXA4, HOXA5 and HOXB4 provide the spatial information needed to restrict the response to signals from the notochord, and not up regulated in pancreatic cancer. PMID: 21546695
    8. Results confirm that HOXA4 inhibits cell motility, show that it suppresses cell spreading and filopodia formation while enhancing cell-cell adhesion, and suggest a role for beta1 integrin in mediating these changes. PMID: 19723874
    9. upregulated significantly in acute myeloid leukemia patients with a white blood cell count higher than 30 x 10(9)/L cells. PMID: 12031912
    10. aberrant DNA methylation may have a major role in the control of HOXA4 gene expression in chronic lymphocytic leukemia PMID: 16688227
    11. analysis of the role of deregulated PcG genes in acute myeloid leukemia, and the downstream PcG targets HOXA4, HOXA9 and MEIS1 PMID: 18410541
    12. combination of low HOXA4 and low MEIS1 gene expression is a favourable predictor for outcome in all AML patients and that the expression levels are governed by the methylation state of these genes. PMID: 19563517

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Antp homeobox family, Deformed subfamily
  • 組織特異性：
    Embryonic nervous system.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 5105

    OMIM: 142953

    KEGG: hsa:3201

    STRING: 9606.ENSP00000353151

    UniGene: Hs.533357



主站蜘蛛池模板： 欧美村妇激情内射| 久久青草费线频观看| 国产成人综合色在线观看网站| 色婷婷五月综合激情中文字幕 | 国内精品久久久人妻中文字幕| 十八禁真人啪啪免费网站| 无码人妻专区免费视频| 国产偷窥熟女高潮精品视频| 中文字幕无线码一区二区| 午夜福利理论片高清在线| 亚洲欧洲精品无码av| 日韩高清国产一区在线| 九九热在线视频观看这里只有精品 | 亚洲精品无码专区| 亚洲色播爱爱爱爱爱爱爱 | 亚洲国产精品综合久久网各| 亚洲免费综合色在线视频| 极品少妇一区二区三区四区| 熟女人妻水多爽中文字幕| 国产成人无码免费视频在线| 宅男午夜成年影视在线观看| 国产偷国产偷亚州清高app| 情侣黄网站免费看| 99re6热视频这里只精品首页| 无码av片在线观看免费| 国产视频一区二区| 国产亚洲日韩欧美另类第八页| 午夜伦yy44880影院| 青青草无码精品伊人久久| 国产香蕉尹人视频在线| 国产乱对白刺激视频| 性欧美丰满熟妇xxxx性5| 男ji大巴进入女人的直播| 99久久国产露脸国语对白| 国产成人a区在线观看| 图片区小说区亚洲欧美自拍| 国产精品污www一区二区三区| 亚欧美日韩香蕉在线播放视频| 欧美性video高清精品| 亚洲日本成本人观看| 精品少妇ay一区二区三区|