在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HOXA4 Antibody

HOXA4 Antibody

  • 中文名稱：
    HOXA4兔多克隆抗體
  • 貨號：
    CSB-PA090969
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA090969(HOXA4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA090969(HOXA4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    HOXA4
  • 別名：
    Dfd like protein antibody; Homeo box A4 antibody; Homeobox A4 antibody; Homeobox protein Hox-1.4 antibody; Homeobox protein Hox-1D antibody; Homeobox protein Hox-A4 antibody; Hox 1.4 like protein antibody; hox-1.4 antibody; hox-1d antibody; HOX1 antibody; HOX1D antibody; HOXA4 antibody; HXA4_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human HOXA4
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to sites in the 5'-flanking sequence of its coding region with various affinities. The consensus sequences of the high and low affinity binding sites are 5'-TAATGA[CG]-3' and 5'-CTAATTTT-3'.
  • 基因功能參考文獻：
    1. HOXA4/HOXB3 gene expression-based risk score may be useful for prognostic risk stratification and warrants prospective validation in HGSOC patients. PMID: 29402501
    2. Overexpression of HOXA4 and HOXA9 contributes to self-renewal and overpopulation of stem cells in colorectal cancers. PMID: 28464221
    3. HOXA4 increases short-term repopulation to higher levels than HOXB4, which may involve Notch signaling to induce self-renewal of primitive hematopoietic cells PMID: 26166023
    4. The NK AML patients with NPM1 mutations exhibited elevated HOXA4 methylation and expression levels of HOXA5 and MEIS1 compared with the NPM1 wildtype patients. PMID: 25585874
    5. promoter hypermethylation of HOXA4 gene could be an epigenetic mechanism mediating IM resistance in CML patients. PMID: 23484077
    6. HOXA4 showed nuclear & perinuclear staining in endothelial & smooth muscle cells in aorta. Spatial variation in expression in human aortas persisted into adulthood. Downregulation of HOXA4 expression was associated with abdominal aortic aneurysm. PMID: 21627813
    7. Studies suggest that HOXA4, HOXA5 and HOXB4 provide the spatial information needed to restrict the response to signals from the notochord, and not up regulated in pancreatic cancer. PMID: 21546695
    8. Results confirm that HOXA4 inhibits cell motility, show that it suppresses cell spreading and filopodia formation while enhancing cell-cell adhesion, and suggest a role for beta1 integrin in mediating these changes. PMID: 19723874
    9. upregulated significantly in acute myeloid leukemia patients with a white blood cell count higher than 30 x 10(9)/L cells. PMID: 12031912
    10. aberrant DNA methylation may have a major role in the control of HOXA4 gene expression in chronic lymphocytic leukemia PMID: 16688227
    11. analysis of the role of deregulated PcG genes in acute myeloid leukemia, and the downstream PcG targets HOXA4, HOXA9 and MEIS1 PMID: 18410541
    12. combination of low HOXA4 and low MEIS1 gene expression is a favourable predictor for outcome in all AML patients and that the expression levels are governed by the methylation state of these genes. PMID: 19563517

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Antp homeobox family, Deformed subfamily
  • 組織特異性：
    Embryonic nervous system.
  • 數據庫鏈接：

    HGNC: 5105

    OMIM: 142953

    KEGG: hsa:3201

    STRING: 9606.ENSP00000353151

    UniGene: Hs.533357



主站蜘蛛池模板： 国产激情大臿免费视频| 中国亚洲女人69内射少妇| 国内精品久久久人妻中文字幕| 欧美成人精品福利视频| 97色伦午夜国产亚洲精品| 99精品人妻少妇一区二区| 在线看免费无码av天堂| 无修无码h里番在线播放网站| 人妻熟女一区二区aⅴ水野朝阳| 亚洲老熟女性亚洲| 久久无码专区国产精品s | 亚洲精品乱码久久久久久蜜桃| 超碰色偷偷男人的天堂| 四虎成人欧美精品在永久在线| 欧美专区另类专区在线视频| 激情五月婷婷| 色8久久人人97超碰香蕉987| 在线人视频观看免费| av无码久久久久不卡网站蜜桃| 午夜福利视频| 2017亚洲天堂最新地址| 99精品国产高清一区二区麻豆| 日本一区二区三区免费高清| 欧洲熟妇牲交| 久久精品人人做人人爽老司机| 久久精品aⅴ无码中文字字幕| 无码国产精品一区二区高潮| 人人爽人人模人人人爽人人爱| 日韩av高潮喷水在线观看| 国产人成无码视频在线观看| 色综合视频一区二区三区| 色欲久久综合亚洲精品蜜桃| 国产卡1卡2卡3麻豆精品免费| 亚洲欧美中文日韩v在线观看| 国产精品人成视频国模| 国产成人无码激情视频| 日韩av无码一区二区三区不卡| 国产69久久精品成人看| 丰满少妇aaaaaa爰片毛片 | av第一福利网站| 性色av无码一区二区三区人妻|