在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HOXA4 Antibody, HRP conjugated

  • 中文名稱:
    HOXA4兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA010654LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) HOXA4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HOXA4
  • 別名:
    Dfd like protein antibody; Homeo box A4 antibody; Homeobox A4 antibody; Homeobox protein Hox-1.4 antibody; Homeobox protein Hox-1D antibody; Homeobox protein Hox-A4 antibody; Hox 1.4 like protein antibody; hox-1.4 antibody; hox-1d antibody; HOX1 antibody; HOX1D antibody; HOXA4 antibody; HXA4_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Homeobox protein Hox-A4 protein (23-173AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to sites in the 5'-flanking sequence of its coding region with various affinities. The consensus sequences of the high and low affinity binding sites are 5'-TAATGA[CG]-3' and 5'-CTAATTTT-3'.
  • 基因功能參考文獻:
    1. HOXA4/HOXB3 gene expression-based risk score may be useful for prognostic risk stratification and warrants prospective validation in HGSOC patients. PMID: 29402501
    2. Overexpression of HOXA4 and HOXA9 contributes to self-renewal and overpopulation of stem cells in colorectal cancers. PMID: 28464221
    3. HOXA4 increases short-term repopulation to higher levels than HOXB4, which may involve Notch signaling to induce self-renewal of primitive hematopoietic cells PMID: 26166023
    4. The NK AML patients with NPM1 mutations exhibited elevated HOXA4 methylation and expression levels of HOXA5 and MEIS1 compared with the NPM1 wildtype patients. PMID: 25585874
    5. promoter hypermethylation of HOXA4 gene could be an epigenetic mechanism mediating IM resistance in CML patients. PMID: 23484077
    6. HOXA4 showed nuclear & perinuclear staining in endothelial & smooth muscle cells in aorta. Spatial variation in expression in human aortas persisted into adulthood. Downregulation of HOXA4 expression was associated with abdominal aortic aneurysm. PMID: 21627813
    7. Studies suggest that HOXA4, HOXA5 and HOXB4 provide the spatial information needed to restrict the response to signals from the notochord, and not up regulated in pancreatic cancer. PMID: 21546695
    8. Results confirm that HOXA4 inhibits cell motility, show that it suppresses cell spreading and filopodia formation while enhancing cell-cell adhesion, and suggest a role for beta1 integrin in mediating these changes. PMID: 19723874
    9. upregulated significantly in acute myeloid leukemia patients with a white blood cell count higher than 30 x 10(9)/L cells. PMID: 12031912
    10. aberrant DNA methylation may have a major role in the control of HOXA4 gene expression in chronic lymphocytic leukemia PMID: 16688227
    11. analysis of the role of deregulated PcG genes in acute myeloid leukemia, and the downstream PcG targets HOXA4, HOXA9 and MEIS1 PMID: 18410541
    12. combination of low HOXA4 and low MEIS1 gene expression is a favourable predictor for outcome in all AML patients and that the expression levels are governed by the methylation state of these genes. PMID: 19563517

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Antp homeobox family, Deformed subfamily
  • 組織特異性:
    Embryonic nervous system.
  • 數據庫鏈接:

    HGNC: 5105

    OMIM: 142953

    KEGG: hsa:3201

    STRING: 9606.ENSP00000353151

    UniGene: Hs.533357



主站蜘蛛池模板: 国产精品有码无码av在线播放| 人人妻人人澡人人爽欧美二区| 色先锋av影音先锋在线| 三级做a全过程在线观看| 色婷婷五月综合激情中文字幕 | 国产亚洲日本精品无码| 亚洲全部无码中文字幕| 国产成人精品aa毛片| 婷婷五月综合色视频| 大肉大捧一进一出视频出来呀 | h无码精品3d动漫在线观看 | 亚洲精品国产精品制服丝袜| 午夜成人亚洲理论片在线观看| 午夜dv内射一区二区| 亚洲国产精品无码一线岛国| 国产成人av无码精品天堂| 秋秋影视午夜福利高清| 久久久中日ab精品综合| 久久狠狠高潮亚洲精品| 久久精品免视看国产成人明星 | 在线视频国产制服丝袜| 少妇性bbb搡bbb爽爽爽欧美| 国内精品卡一卡二卡三| 国产360激情盗摄全集| 亚洲男同gv在线观看| 久久久国产一区二区三区四区小说| 大香线蕉伊人精品超碰| 日本三级在线播放线观看视频| 两个黑人大战嫩白金发美女| 又黄又爽又色视频免费| 中国少妇内射xxxhd| 日本高清色倩视频在线观看| 人妻激情另类乱人伦人妻| 2021国产精品视频网站| 成人免费午夜无码视频| 草色噜噜噜av在线观看香蕉| 鲁丝片一区二区三区毛片| 免费无码在线播放av| 搡老女人老妇女老熟妇| 久久久久久久久免费看无码| 色综合欧美五月俺也去|