在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HOGA1 Antibody

HOGA1 Antibody

  • 中文名稱：
    HOGA1兔多克隆抗體
  • 貨號：
    CSB-PA771464LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA771464LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of HepG2 cells with CSB-PA771464LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HOGA1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HOGA1
  • 別名：
    HOGA1 antibody; C10orf65 antibody; DHDPSL antibody; 4-hydroxy-2-oxoglutarate aldolase antibody; mitochondrial antibody; EC 4.1.3.16 antibody; Dihydrodipicolinate synthase-like antibody; DHDPS-like protein antibody; Probable 2-keto-4-hydroxyglutarate aldolase antibody; Probable KHG-aldolase antibody; Protein 569272 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human 4-hydroxy-2-oxoglutarate aldolase, mitochondrial protein (1-164AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，HOGA1 Antibody (CSB-PA771464LA01HU)，的標記方式是Non-conjugated。對于HOGA1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA771464LB01HU HOGA1 Antibody, HRP conjugated ELISA
    FITC CSB-PA771464LC01HU HOGA1 Antibody, FITC conjugated
    Biotin CSB-PA771464LD01HU HOGA1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the final step in the metabolic pathway of hydroxyproline.
  • 基因功能參考文獻：
    1. Results show that HOGA1 harboring mutations found in primary hyperoxaluria is thermally unstable and targeted for proteolytic degradation leading to an absolute loss of function. PMID: 27096395
    2. Among the seven patients identified with HOGA1 mutations the median onset of clinical symptoms was 1.8 years. Five patients initially presented with urolithiasis, and two other patients presented with urinary tract infection. PMID: 25972204
    3. Our results strongly suggest HOGA1 as a major cause of PH, indicate a greater genetic heterogeneity of hyperoxaluria, and point to a favorable outcome of type III in the context of PH despite incomplete or absent biochemical remission PMID: 22781098
    4. seven different mutations were identified in primary hyperoxaluria type 3 PMID: 22391140
    5. Two crystal forms of DHDPSL were obtained, both of which diffracted X-rays to approximately 2.0 A resolution PMID: 22232173
    6. hHOGA utilizes a type I aldolase reaction mechanism, but employs novel residue interactions for substrate binding PMID: 21998747
    7. Detection of HOGA1 variants in idiopathic calcium oxalate urolithiasis also suggests HOGA1 may be a predisposing factor for this condition PMID: 21896830
    8. DHDPSL is the gene encoding 4-hydroxy-2-oxoglutarate aldolase, catalyzing the final step in the metabolic pathway of hydroxyproline. PMID: 20797690

    顯示更多

    收起更多

  • 相關疾病：
    Hyperoxaluria primary 3 (HP3)
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    DapA family
  • 數據庫鏈接：

    HGNC: 25155

    OMIM: 613597

    KEGG: hsa:112817

    STRING: 9606.ENSP00000359680

    UniGene: Hs.180346



主站蜘蛛池模板： 成品人视频ww入口| 国产男女猛烈无遮挡免费视频网站| 久久久久国产精品嫩草影院| 激情欧美日韩一区二区| 国产 | 欧洲野花视频欧洲1| 99久久久国产精品消防器材| 少妇被躁爽到高潮无码人狍大战| 国产69精品久久久久久久| 手机看片国产av无码| 国产精品高潮呻吟av久久黄| 亚洲精品nv久久久久久久久久| 午夜理论片yy44880影院| 亚洲中文字幕av无码区| 中文字幕久久精品无码| 国产精品激情av久久久青桔| 午夜免费福利小电影| 青乐娱精品视频一国产分类| 欧美自拍另类欧美综合图片区| 日本人妻丰满熟妇久久久久久 | 亚洲久久中文字幕www网站| 色播在线精品一区二区三区四区| 极品少妇高潮到爽| 亚洲色偷偷色噜噜狠狠99网| 2018天天躁夜夜躁狠狠躁| 国产成人午夜福利免费无码r| 亚洲人成中文字幕在线观看| 日躁夜躁狠狠躁2001| 久久66热人妻偷产精品| 超薄肉色丝袜一区二区| 99久久无码私人网站| 日韩精品无码免费一区二区三区| 公与淑婷厨房猛烈进出视频免费| 日本免费大黄在线观看| 不卡无码av一区二区三区| 国内偷窥一区二区三区视频| 四虎影视在线影院在线观看免费视频 | 欧美日激情日韩精品嗯| 国产成_人_综合_亚洲_国产| 亚洲人av高清无码| 电影内射视频免费观看| 狠狠色噜噜狠狠狠狠五月婷 |