在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HOGA1 Antibody

HOGA1 Antibody

  • 中文名稱：
    HOGA1兔多克隆抗體
  • 貨號：
    CSB-PA771464LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA771464LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of HepG2 cells with CSB-PA771464LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HOGA1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HOGA1
  • 別名：
    HOGA1 antibody; C10orf65 antibody; DHDPSL antibody; 4-hydroxy-2-oxoglutarate aldolase antibody; mitochondrial antibody; EC 4.1.3.16 antibody; Dihydrodipicolinate synthase-like antibody; DHDPS-like protein antibody; Probable 2-keto-4-hydroxyglutarate aldolase antibody; Probable KHG-aldolase antibody; Protein 569272 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human 4-hydroxy-2-oxoglutarate aldolase, mitochondrial protein (1-164AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，HOGA1 Antibody (CSB-PA771464LA01HU)，的標記方式是Non-conjugated。對于HOGA1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA771464LB01HU HOGA1 Antibody, HRP conjugated ELISA
    FITC CSB-PA771464LC01HU HOGA1 Antibody, FITC conjugated
    Biotin CSB-PA771464LD01HU HOGA1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the final step in the metabolic pathway of hydroxyproline.
  • 基因功能參考文獻：
    1. Results show that HOGA1 harboring mutations found in primary hyperoxaluria is thermally unstable and targeted for proteolytic degradation leading to an absolute loss of function. PMID: 27096395
    2. Among the seven patients identified with HOGA1 mutations the median onset of clinical symptoms was 1.8 years. Five patients initially presented with urolithiasis, and two other patients presented with urinary tract infection. PMID: 25972204
    3. Our results strongly suggest HOGA1 as a major cause of PH, indicate a greater genetic heterogeneity of hyperoxaluria, and point to a favorable outcome of type III in the context of PH despite incomplete or absent biochemical remission PMID: 22781098
    4. seven different mutations were identified in primary hyperoxaluria type 3 PMID: 22391140
    5. Two crystal forms of DHDPSL were obtained, both of which diffracted X-rays to approximately 2.0 A resolution PMID: 22232173
    6. hHOGA utilizes a type I aldolase reaction mechanism, but employs novel residue interactions for substrate binding PMID: 21998747
    7. Detection of HOGA1 variants in idiopathic calcium oxalate urolithiasis also suggests HOGA1 may be a predisposing factor for this condition PMID: 21896830
    8. DHDPSL is the gene encoding 4-hydroxy-2-oxoglutarate aldolase, catalyzing the final step in the metabolic pathway of hydroxyproline. PMID: 20797690

    顯示更多

    收起更多

  • 相關疾病：
    Hyperoxaluria primary 3 (HP3)
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    DapA family
  • 數據庫鏈接：

    HGNC: 25155

    OMIM: 613597

    KEGG: hsa:112817

    STRING: 9606.ENSP00000359680

    UniGene: Hs.180346



主站蜘蛛池模板： 久久成人影院精品777| 极品少妇被猛得白浆直喷白浆小说| 亚洲色播永久网址大全| 亚洲女人被黑人巨大进入| 无码国产伦一区二区三区视频| 香港三级韩国三级日本三级| 亚洲精品久久久一二三区 | 久久青青草原精品国产app| 日本 精品 高清不卡| 男人j进入女人j内部免费网站| 天堂а√在线中文在线新版 | 国产午夜免费高清久久影院| 国产精品二区一区二区aⅴ污介绍| 亚洲精品国产精品国自产观看| 日韩欧美中文字幕在线三区| 亚洲一区爱区精品无码| 欧美成人a在线网站| 国产乱子伦一区二区三区| 国产在线精品无码不卡手机免费| 中老年熟妇激情啪啪大屁股| 久久久久久久综合狠狠综合| 8天堂资源在线| 亚洲精品国产情侣av在线| 日产精品卡二卡三卡四卡区满十八| 无码国产精品一区二区免费式影视| 青草内射中出高潮| 人人婷婷人人澡人人爽| 最新亚洲人成无码网站| 亚洲人成色7777在线观看| 国产成人无码牲交免费视频| 国产精品调教视频一区| 精品欧洲av无码一区二区| 国产亚洲精品久久久久久小说| 久久精品国产精品亚洲38| 国产精品日韩欧美一区二区三区| 性大毛片视频| 色视频无码专区在线观看| 人人人妻人人人妻人人人| 亚洲妇熟xxxx妇色黄| 亚洲精品拍拍央视网出文| av 日韩 人妻 黑人 综合 无码|