在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HOGA1 Antibody, HRP conjugated

  • 中文名稱:
    HOGA1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA771464LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) HOGA1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HOGA1
  • 別名:
    HOGA1 antibody; C10orf65 antibody; DHDPSL antibody; 4-hydroxy-2-oxoglutarate aldolase antibody; mitochondrial antibody; EC 4.1.3.16 antibody; Dihydrodipicolinate synthase-like antibody; DHDPS-like protein antibody; Probable 2-keto-4-hydroxyglutarate aldolase antibody; Probable KHG-aldolase antibody; Protein 569272 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human 4-hydroxy-2-oxoglutarate aldolase, mitochondrial protein (1-164AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the final step in the metabolic pathway of hydroxyproline.
  • 基因功能參考文獻:
    1. Results show that HOGA1 harboring mutations found in primary hyperoxaluria is thermally unstable and targeted for proteolytic degradation leading to an absolute loss of function. PMID: 27096395
    2. Among the seven patients identified with HOGA1 mutations the median onset of clinical symptoms was 1.8 years. Five patients initially presented with urolithiasis, and two other patients presented with urinary tract infection. PMID: 25972204
    3. Our results strongly suggest HOGA1 as a major cause of PH, indicate a greater genetic heterogeneity of hyperoxaluria, and point to a favorable outcome of type III in the context of PH despite incomplete or absent biochemical remission PMID: 22781098
    4. seven different mutations were identified in primary hyperoxaluria type 3 PMID: 22391140
    5. Two crystal forms of DHDPSL were obtained, both of which diffracted X-rays to approximately 2.0 A resolution PMID: 22232173
    6. hHOGA utilizes a type I aldolase reaction mechanism, but employs novel residue interactions for substrate binding PMID: 21998747
    7. Detection of HOGA1 variants in idiopathic calcium oxalate urolithiasis also suggests HOGA1 may be a predisposing factor for this condition PMID: 21896830
    8. DHDPSL is the gene encoding 4-hydroxy-2-oxoglutarate aldolase, catalyzing the final step in the metabolic pathway of hydroxyproline. PMID: 20797690

    顯示更多

    收起更多

  • 相關疾病:
    Hyperoxaluria primary 3 (HP3)
  • 亞細胞定位:
    Mitochondrion.
  • 蛋白家族:
    DapA family
  • 數據庫鏈接:

    HGNC: 25155

    OMIM: 613597

    KEGG: hsa:112817

    STRING: 9606.ENSP00000359680

    UniGene: Hs.180346



主站蜘蛛池模板: 久久亚洲国产成人精品性色| 一区一区三区产品乱码亚洲| 亚洲国产成人无码电影| 免费做a爰片久久毛片a片| 亚洲熟妇久久精品| 日本亲与子乱人妻hd| 日韩av片无码一区二区三区| 国产女厕所盗摄老师厕所嘘嘘| 亚洲日韩国产精品第一页一区| 日本老熟妇毛茸茸| 国产精品国语对白露脸在线播放 | 99噜噜噜在线播放| 天天做天天爱天天综合网2021| 亚洲精品无码你懂的| 国农村精品国产自线拍| 欧美老熟妇videos极品另类| 亚洲精品天天影视综合网| 国产高清视频色拍| 四虎av永久在线精品免费观看| 亚洲人成在线观看| 成人国产精品无码网站| 无码人妻一区二区三区四区av| 久久综合九色综合网站| 中国熟妇牲交视频| 韩国无码色视频在线观看| 377p欧洲日本亚洲大胆| 对白脏话肉麻粗话av| 人人狠狠综合久久88成人| 麻豆精品久久久久久中文字幕无码| 久久人妻天天av| 国产精品久久久久久麻豆一区| 不卡无码人妻一区二区三区 | 无码av无码天堂资源网影音先锋| 亚洲国产精品第一区二区| 久久婷婷五月综合色国产香蕉 | 国产午夜福利在线观看视频_ | 在线 v亚洲 v欧美v 专区| 成人欧美一区二区三区黑人| 看国产黄大片在线观看| 国精产品蘑菇一区一区有限| 久久久久国色av免费看|