在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HINT2 Antibody

HINT2 Antibody

  • 中文名稱：
    HINT2兔多克隆抗體
  • 貨號：
    CSB-PA955413
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA955413(HINT2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA955413(HINT2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    HINT2
  • 別名：
    1190005L05Rik antibody; HINT-2 antibody; HINT-3 antibody; HINT2 antibody; HINT2_HUMAN antibody; histidine triad nucleotide binding protein 2 antibody; Histidine triad nucleotide-binding protein 2 antibody; HIT-17 antibody; HIT-17kDa antibody; mitochondrial antibody; PKCI-1-related HIT protein antibody; Protein kinase C inhibitor 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human HINT2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2. Hydrolyzes adenosine 5'-O-p-nitrophenylphosphoramidate (AMP-pNA). Hydrolyzes fluorogenic purine nucleoside tryptamine phosphoramidates in vitro. May be involved in steroid biosynthesis. May play a role in apoptosis.
  • 基因功能參考文獻：
    1. Authors deduced that HINT2 triggers apoptosis in pancreatic cancer cells by regulating mitochondrial Ca(2+) influx through the mitochondrial calcium uniporter (MCU). Authors found that HINT2 can sensitize BxPC-3 and L3.6pl cells to gemcitabine-induced apoptosis and that gemcitabine up-regulates HINT2 expression. PMID: 28947137
    2. HINT2 downregulation depended on hypoxia inducible factor (HIF)-2alpha-mediated transcriptional activation of zinc finger E-box-binding homeobox 1 (ZEB1). These results suggest that HINT2 downregulation promotes HIF-2alpha expression, which induces EMT and enhances CRC cell migration and invasion. PMID: 28088787
    3. Low HINT2 expression is associated with low response to therapy in endometrial cancer. PMID: 23682076
    4. X-ray crystal structure of human HINT2 with and without bound AMP. PMID: 23659632
    5. Hint2 is required for an optimal steroidogenic response, possibly because of a particular signalling function exerted within the mitochondria. PMID: 18653718

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    HINT family
  • 組織特異性：
    High expression in liver and pancreas. Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients.
  • 數據庫鏈接：

    HGNC: 18344

    OMIM: 609997

    KEGG: hsa:84681

    STRING: 9606.ENSP00000259667

    UniGene: Hs.70573



主站蜘蛛池模板： 久久99成人免费| 亚洲色无码专区在线观看精品| av香港经典三级级 在线| 男人女人午夜视频免费| 国产在线观看超清无码视频一区二区| 九色精品国产成人综合网站| 亚洲一区精品无码色成人| 亚洲精品无码不卡在线播放| 中文字幕 人妻熟女| 学生妹亚洲一区二区| 日韩精品久久久肉伦网站| 亚洲vs成人无码人在线观看堂| 纯肉无遮挡h肉动漫在线观看国产| 2020无码天天喷水天天爽| 丁香五月欧美成人| 亚洲精品国产精品乱码视色| 日本边添边摸边做边爱喷水| 麻豆ā片免费观看在线看| 久久精品亚洲综合专区| 无码免费一区二区三区| 中年熟妇的大黑p| 中文字幕亚洲制服在线看| 韩国三级无码hd中文字幕| 中文字幕丝袜第1页| 亚洲高清最新av网站| 2018国产精华国产精品| 国产粗话肉麻对白在线播放| 夜夜夜夜猛噜噜噜噜噜试看| 国产男女猛烈无遮挡免费视频网站| 精品无码一区二区三区| 色婷婷久久久swag精品| 亚洲精品久久一区二区三区四区| 久热中文字幕无码视频| 免费无码肉片在线观看| 国产xxx69麻豆国语对白| 暖暖 免费 高清 日本 在线| 国产经典三级av在线播放| 亚洲中文字幕无码久久2018| 色综合久久无码中文字幕 | 日韩精品乱码av一区二区| 免费人成网站视频在线观看|