在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HCLS1 (Ab-397) Antibody

HCLS1 (Ab-397) Antibody

  • 中文名稱：
    HCLS1 (Ab-397)兔多克隆抗體
  • 貨號：
    CSB-PA790699
  • 規格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from JK cells (Lane 2), using HS1 (Ab-397) antiobdy. The lane on the left is treated with synthesized peptide.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HCLS1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HCLS1
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from C-terminal of Human HCLS1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
  • 基因功能參考文獻：
    1. these studies indicate HS1 plays an important role in ROR1-dependent Wnt5a-enhanced chemokine-directed leukemia-cell migration. PMID: 28465529
    2. SDF1alpha-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells. PMID: 25359136
    3. Phosphoproteome analyses reveal specific implications of Hcls1, p21-activated kinase 1 and Ezrin in proliferation of a myeloid progenitor cell line downstream of wild-type and ITD mutant Fms-like tyrosine kinase 3 receptors. PMID: 23017497
    4. interaction of HCLS1 with LEF-1 is essential for G-CSF-triggered myeloid differentiation; data demonstrate the importance of HCLS1 in myelopoiesis in vitro and in vivo PMID: 23001182
    5. HS1 overexpressed in leukemic as compared to normal B lymphocytes. PMID: 22768161
    6. a novel role for HS1 and its phosphorylation during neutrophil directed migration. PMID: 22679023
    7. High HS1 expression predicts poor survival of chronic lymphocytic leukemia patients. PMID: 22333038
    8. SH3 domain of HS1 protein recognizes lysine-rich polyproline motifs. PMID: 21287358
    9. HS1 is a central regulator of cytoskeleton remodeling that controls lymphocyte trafficking and homing and significantly influences the tissue invasion and infiltration in chronic lymphocytic leukemia. PMID: 20530793
    10. substrate for caspase cleavage during apoptosis PMID: 11689006
    11. TBB induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells. PMID: 11988074
    12. found in cell types other than hematopoietic cells PMID: 15754022
    13. HS1 Tyr phosphorylation catalyzed by Syk and Lyn plays a crucial role in the translocation of the protein to the membrane and is involved in the cytoskeleton rearrangement triggered by thrombin in human platelets PMID: 15795233
    14. The HS1 coiled-coil region acts synergistically with the repeat domain in the modulation of the Arp2/3 complex-mediated actin polymerization. PMID: 16157603
    15. HS1 may play a role in cytoskeleon organization in B-cells and leukemic B-cells PMID: 17508001

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Peripheral membrane protein. Cytoplasm. Mitochondrion.
  • 組織特異性：
    Expressed only in tissues and cells of hematopoietic origin.
  • 數據庫鏈接：

    HGNC: 4844

    OMIM: 601306

    KEGG: hsa:3059

    STRING: 9606.ENSP00000320176

    UniGene: Hs.14601



主站蜘蛛池模板： 亚洲中文无码a∨在线观看| 天天躁日日躁狠狠躁av麻豆男男| 日本不卡高字幕在线2019| 极品粉嫩国产18尤物在线观看| 亚洲成国产人片在线观看| 亚洲另类色区欧美日韩图片| 天美传媒一区二区| 韩国精品一区二区三区无码视频| 国产福利日本一区二区三区| 日本动漫瀑乳h动漫啪啪免费| 国产三级在线观看完整版| 国产精品无码一区二区在线| 天天做天天欢摸夜夜摸狠狠摸| 亚洲色无码专区在线观看| 色天使久久综合网天天| 夜夜夜高潮夜夜爽夜夜爰爰 | 香蕉噜噜噜噜私人影院| 四虎免费最新在线永久4hu| 午夜影视免费| 国产69精品久久久久人妻刘玥| 亚洲 日韩 欧美 成人 在线| 四虎影库久免费视频| 久久人人爽人人人人片| 亚洲va久久久噜噜噜久久天堂| 国产成人啪精品视频免费视频| 亚洲色精品三区二区一区| 丰满人妻熟妇乱又伦精品视| 亚洲国产欧美在线人成大黄瓜| 亚洲精品久久久久国产剧8| 国产亚洲精品俞拍视频| 少妇内射视频播放舔大片| 亚洲乱码日产精品bd| 日韩精品亚洲人成在线观看| 无码人妻一区二区三区免费看| 狠狠躁夜夜躁人人爽天天古典| 中文无码日韩欧av影视| 精产国品一二三产区m553麻豆| 色先锋资源久久综合5566| 久在线视视频在线观看| 国产成人av综合色| 无码少妇精品一区二区免费动态|