在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HCLS1 (Ab-397) Antibody

HCLS1 (Ab-397) Antibody

  • 中文名稱：
    HCLS1 (Ab-397)兔多克隆抗體
  • 貨號：
    CSB-PA790699
  • 規格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from JK cells (Lane 2), using HS1 (Ab-397) antiobdy. The lane on the left is treated with synthesized peptide.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HCLS1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HCLS1
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from C-terminal of Human HCLS1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
  • 基因功能參考文獻：
    1. these studies indicate HS1 plays an important role in ROR1-dependent Wnt5a-enhanced chemokine-directed leukemia-cell migration. PMID: 28465529
    2. SDF1alpha-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells. PMID: 25359136
    3. Phosphoproteome analyses reveal specific implications of Hcls1, p21-activated kinase 1 and Ezrin in proliferation of a myeloid progenitor cell line downstream of wild-type and ITD mutant Fms-like tyrosine kinase 3 receptors. PMID: 23017497
    4. interaction of HCLS1 with LEF-1 is essential for G-CSF-triggered myeloid differentiation; data demonstrate the importance of HCLS1 in myelopoiesis in vitro and in vivo PMID: 23001182
    5. HS1 overexpressed in leukemic as compared to normal B lymphocytes. PMID: 22768161
    6. a novel role for HS1 and its phosphorylation during neutrophil directed migration. PMID: 22679023
    7. High HS1 expression predicts poor survival of chronic lymphocytic leukemia patients. PMID: 22333038
    8. SH3 domain of HS1 protein recognizes lysine-rich polyproline motifs. PMID: 21287358
    9. HS1 is a central regulator of cytoskeleton remodeling that controls lymphocyte trafficking and homing and significantly influences the tissue invasion and infiltration in chronic lymphocytic leukemia. PMID: 20530793
    10. substrate for caspase cleavage during apoptosis PMID: 11689006
    11. TBB induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells. PMID: 11988074
    12. found in cell types other than hematopoietic cells PMID: 15754022
    13. HS1 Tyr phosphorylation catalyzed by Syk and Lyn plays a crucial role in the translocation of the protein to the membrane and is involved in the cytoskeleton rearrangement triggered by thrombin in human platelets PMID: 15795233
    14. The HS1 coiled-coil region acts synergistically with the repeat domain in the modulation of the Arp2/3 complex-mediated actin polymerization. PMID: 16157603
    15. HS1 may play a role in cytoskeleon organization in B-cells and leukemic B-cells PMID: 17508001

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Peripheral membrane protein. Cytoplasm. Mitochondrion.
  • 組織特異性：
    Expressed only in tissues and cells of hematopoietic origin.
  • 數據庫鏈接：

    HGNC: 4844

    OMIM: 601306

    KEGG: hsa:3059

    STRING: 9606.ENSP00000320176

    UniGene: Hs.14601



主站蜘蛛池模板： 久久午夜羞羞影院免费观看| 97精品久久久久中文字幕| 国产精品视频免费播放| 久久精品中文字幕一区二区三区| 黑人好猛厉害爽受不了好大撑| 18禁亚洲深夜福利人口| 精品国产三级a在线观看| 亚洲 欧美 另类 综合 日韩| 亚洲欧洲久久av| 欧美亚洲高清国产| 亚洲国产av精品一区二区蜜芽 | 99久久99视频只有精品| 熟妇人妻无乱码中文字幕| 国产精品一久久香蕉国产线看观看 | 欧美精品黑人粗大破除| 香蕉在线 亚洲 欧美 专区| 在线精品视频一区二区三区| 综合 欧美 亚洲日本| 久久视频在线视频| 国产精品嫩草影院久久| 国产美女视频免费观看网址| 国产麻豆剧果冻传媒白晶晶| 少妇人妻系列无码专区视频| 欧洲-级毛片内射| 果冻传媒mv免费播放在线观看| 国产 日韩 另类 视频一区| 国内揄拍国内精品少妇| 苍井空张开腿实干12次| 亚洲精品国产av成拍色拍个| 影音先锋中文无码一区| 樱花草在线社区www中国| 一本无码久本草在线中文字幕dvd 337p日本欧洲亚洲大胆裸体艺术 国产av一区二区三区 | 国产偷国产偷亚洲清高孕妇| 日本另类αv欧美另类aⅴ| 亚洲精品乱码久久久久久日本| 久久久精品2020免费观看| 一区二区三区鲁丝不卡麻豆 | 国产农村乱辈无码| 好吊妞国产欧美日韩免费观看| 全黄激性性视频| 秋霞鲁丝无码一区二区三区|