在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HCCS Antibody

  • 中文名稱:
    HCCS兔多克隆抗體
  • 貨號(hào):
    CSB-PA010165ESR1HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: HCCS antibody at 3.54µg/ml
      Lane 1: Mouse small intestine tissue
      Lane 2: Mouse heart tissue
      Lane 3: Mouse skeletal muscle tissue
      Lane 4: Hela whole cell lysate
      Lane 5: RAW264.7 whole cell lysate
      Lane 6: MCF-7 whole cell lysate
      Lane 7: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 31 kDa
      Observed band size: 31 kDa
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) HCCS Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HCCS
  • 別名:
    CCHL antibody; CCHL_HUMAN antibody; cytochrome c heme-lyase antibody; Cytochrome c-type heme lyase antibody; DKFZp779I1858 antibody; EC 4.4.1.17 antibody; Hccs antibody; Holocytochrome c synthase (cytochrome c heme lyase) antibody; Holocytochrome c synthase antibody; Holocytochrome c type synthase antibody; Holocytochrome c-type synthase antibody; MCOPS7 antibody; OTTHUMP00000022903 antibody; OTTHUMP00000022904 antibody; OTTHUMP00000022905 antibody; OTTMUSP00000021173 antibody; OTTMUSP00000021174 antibody; RGD1563855 antibody; RP23-37L2.1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Cytochrome c-type heme lyase protein (1-268AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
  • 基因功能參考文獻(xiàn):
    1. Data suggest that although HCCS mediates heme attachment to N-terminal cysteine in heme-attachment site (CXXXH) of cytochrome C variants, up to 50% of cytochrome C produced is modified in an oxygen-dependent manner, resulting in a mixed population of cytochrome c. [HCCS = holocytochrome c synthase] PMID: 28617588
    2. Bacterial cyt c biogenesis pathways (Systems I and II) appear to recognize simply the CXXCH motif, not requiring alpha helix-1. Results here explain mechanistically how HCCS (System III) requires an extended region adjacent to CXXCH for maturation. PMID: 27387500
    3. cysteines and histidine of the heme attachment site, Cys-XX-Cys-His play a key role in mitochondrial holocytochrome c synthase PMID: 25170082
    4. These data indicate that heme contacts mediated by residues within these domains modulate the dynamics of heme binding and contribute to the stability of the HCCS-heme-cytochrome c steady state ternary complex. PMID: 25054239
    5. Identification of a deletion in two patients, including HCCS, leads to the diagnosis of microphthalmia with linear skin defects syndrome PMID: 23401659
    6. Spectroscopic analyses of HCCS alone and complexes of HCCS with site-directed variants of cytochrome c revealed the fundamental steps of heme attachment and maturation. PMID: 23150584
    7. Through the study of genetically engineered mice, the loss of HCCS is demonstrated to cause the male lethality of microphthalmia with linear skin defects (MLS) syndrome. PMID: 12444108
    8. mutant proteins (R217C and Delta 197-268) were unable to complement a Saccharomyces cerevisiae mutant deficient for the HCCS orthologue Cyc3p, in contrast to wild-type HCCS PMID: 17033964
    9. Missense mutation p.E159K of HCCS, leading to loss-of-function of encoded holocytochrome c-type synthase, in female with microphthalmia of both eyes and bilateral sclerocornea may suggest HCCS as candidate for severe ocular manifestations. PMID: 17893649

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Linear skin defects with multiple congenital anomalies 1 (LSDMCA1)
  • 亞細(xì)胞定位:
    Mitochondrion inner membrane. Membrane; Lipid-anchor.
  • 蛋白家族:
    Cytochrome c-type heme lyase family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 4837

    OMIM: 300056

    KEGG: hsa:3052

    STRING: 9606.ENSP00000326579

    UniGene: Hs.211571



主站蜘蛛池模板: 欧美老妇bbbwwbbbww| 丰满人妻被黑人猛烈进入| 国产精品自在欧美一区| 免费观看的av在线播放| 国产亚洲色婷婷久久99精品| 成在人线av无码免费看| 久久天天躁狠狠躁夜夜躁2012| 亚洲精品四区麻豆文化传媒| 亚洲人成电影综合网站色www| 欧美欧洲成本大片免费| 亚洲人成色777777老人头| 国内老熟妇对白hdxxxx| 亚洲精品无码av黄瓜影视| 欧美日韩人成视频在线播放| 亚洲一卡2卡3卡4卡5卡乱码观看| 1000部啪啪未满十八勿入| 中文天堂在线www| 国产av激情无码久久| 麻豆av字幕无码中文| 国产裸体xxxx视频在线播放| www夜片内射视频在观看视频| 大肉大捧一进一出好爽视频| 亚洲va久久久噜噜噜久久4399| 日日碰日日摸夜夜爽无码| 久久久一本精品99久久精品88| 无码av波多野结衣| 好男人日本社区www| 欧美天天拍在线视频| 国产午夜片无码区在线播放| 国产精品丝袜久久久久久不卡| 成人电线在线播放无码| 天天狠天天添日日拍| 67194熟妇在线观看线路| 人妻熟人中文字幕一区二区| 无码人妻巨屁股系列| 日本免费一区二区三区四区五区| 午夜男女爽爽影院免费视频下载| 国产精品亚洲片在线观看不卡| 特级毛片全部免费播放| 九九精品99久久久香蕉| 一本久道高清无码视频|