在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HCCS Antibody

  • 中文名稱:
    HCCS兔多克隆抗體
  • 貨號:
    CSB-PA010165GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    HCCS
  • 別名:
    CCHL antibody; CCHL_HUMAN antibody; cytochrome c heme-lyase antibody; Cytochrome c-type heme lyase antibody; DKFZp779I1858 antibody; EC 4.4.1.17 antibody; Hccs antibody; Holocytochrome c synthase (cytochrome c heme lyase) antibody; Holocytochrome c synthase antibody; Holocytochrome c type synthase antibody; Holocytochrome c-type synthase antibody; MCOPS7 antibody; OTTHUMP00000022903 antibody; OTTHUMP00000022904 antibody; OTTHUMP00000022905 antibody; OTTMUSP00000021173 antibody; OTTMUSP00000021174 antibody; RGD1563855 antibody; RP23-37L2.1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human HCCS
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
  • 基因功能參考文獻:
    1. Data suggest that although HCCS mediates heme attachment to N-terminal cysteine in heme-attachment site (CXXXH) of cytochrome C variants, up to 50% of cytochrome C produced is modified in an oxygen-dependent manner, resulting in a mixed population of cytochrome c. [HCCS = holocytochrome c synthase] PMID: 28617588
    2. Bacterial cyt c biogenesis pathways (Systems I and II) appear to recognize simply the CXXCH motif, not requiring alpha helix-1. Results here explain mechanistically how HCCS (System III) requires an extended region adjacent to CXXCH for maturation. PMID: 27387500
    3. cysteines and histidine of the heme attachment site, Cys-XX-Cys-His play a key role in mitochondrial holocytochrome c synthase PMID: 25170082
    4. These data indicate that heme contacts mediated by residues within these domains modulate the dynamics of heme binding and contribute to the stability of the HCCS-heme-cytochrome c steady state ternary complex. PMID: 25054239
    5. Identification of a deletion in two patients, including HCCS, leads to the diagnosis of microphthalmia with linear skin defects syndrome PMID: 23401659
    6. Spectroscopic analyses of HCCS alone and complexes of HCCS with site-directed variants of cytochrome c revealed the fundamental steps of heme attachment and maturation. PMID: 23150584
    7. Through the study of genetically engineered mice, the loss of HCCS is demonstrated to cause the male lethality of microphthalmia with linear skin defects (MLS) syndrome. PMID: 12444108
    8. mutant proteins (R217C and Delta 197-268) were unable to complement a Saccharomyces cerevisiae mutant deficient for the HCCS orthologue Cyc3p, in contrast to wild-type HCCS PMID: 17033964
    9. Missense mutation p.E159K of HCCS, leading to loss-of-function of encoded holocytochrome c-type synthase, in female with microphthalmia of both eyes and bilateral sclerocornea may suggest HCCS as candidate for severe ocular manifestations. PMID: 17893649

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Linear skin defects with multiple congenital anomalies 1 (LSDMCA1)
  • 亞細胞定位:
    Mitochondrion inner membrane. Membrane; Lipid-anchor.
  • 蛋白家族:
    Cytochrome c-type heme lyase family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 4837

    OMIM: 300056

    KEGG: hsa:3052

    STRING: 9606.ENSP00000326579

    UniGene: Hs.211571



主站蜘蛛池模板: 久久中文字幕人妻av熟女| 国产日韩av一区二区三区五区| 国产精品亚洲mnbav网站| 欧美精品免费观看二区| 女人与拘做受全过程免费视频| 国产嫖妓风韵犹存对白| 午夜成人无码片在线观看影院| 国产免费人成在线视频app| 欧美大胆作爱视频欣赏人体| 校花高潮抽搐冒白浆| 亚州中文字幕午夜福利电影| 激情人妻另类人妻伦| 欧洲亚洲色一区二区色99| 粉嫩粉嫩的18在线观看| 欧美色欧美亚洲日韩在线播放| 国产超碰人人做人人爱| 欧美顶级少妇做爰hd| 亚洲第一区无码专区| 亚洲黑人巨大videos| 丰满无码人妻熟妇无码区| 国产精品高清网站| 中文国产成人精品久久不卡| 国产做无码视频在线观看浪潮| 狠狠色狠狠色综合网老熟女| 久久无码中文字幕免费影院| av制服丝袜白丝国产网站| 久久久久国产精品嫩草影院| 久久精品无码一区二区三区| 国产精品高清不卡在线播放| 亚洲精品成人福利网站| 亚洲成a人片在线观看天堂无码| 人妻少妇精品视频一区二区三区| 国产成人啪精品视频网站| 国产多人群p刺激交换视频| 午夜在线观看免费线无码视频| 熟妇人妻av无码一区二区三区| 亚洲va中文字幕无码久久| 色噜噜亚洲男人的天堂www| 国产成人无码一区二区在线播放 | 亚洲日韩精品一区二区三区| 国产99久久久国产精品免费看|