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GNL2 Antibody

  • 中文名稱:
    GNL2兔多克隆抗體
  • 貨號:
    CSB-PA009624GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    GNL2
  • 別名:
    Autoantigen NGP-1 antibody; Autoantigen NGP1 antibody; DJ423B22.6 (novel nucleolar guanosine 5'-triphosphate binding protein antibody; FLJ40906 antibody; GNL2 antibody; Guanine nucleotide binding protein-like 2 (nucleolar) antibody; HUMAUANTIG antibody; NGP1 antibody; NOG2_HUMAN antibody; novel nucleolar guanosine 5'-triphosphate binding protein autoantigen antibody; nucleolar G-protein gene 1 antibody; Nucleolar GTP binding protein 2 antibody; Nucleolar GTP-binding protein 2 antibody; Nucleolar GTPase antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Human GNL2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels.
  • 基因功能參考文獻:
    1. NGP-1 promotes cell cycle progression through the activation of the p53/p21(Cip-1/Waf1) pathway. PMID: 26203195
    2. GNL2 and SEC13 are required for nonsense-mediated mRNA decay pathway in human cells. PMID: 25452588
  • 亞細胞定位:
    Nucleus, nucleolus.
  • 蛋白家族:
    TRAFAC class YlqF/YawG GTPase family, NOG2 subfamily
  • 組織特異性:
    Widely expressed, with the highest expression level in testis.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 29925

    OMIM: 609365

    KEGG: hsa:29889

    STRING: 9606.ENSP00000362153

    UniGene: Hs.75528



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