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  4. GNL2 Antibody

GNL2 Antibody

  • 中文名稱：
    GNL2兔多克隆抗體
  • 貨號：
    CSB-PA618806LA01HU
  • 規格：
    ￥440
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) GNL2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GNL2
  • 別名：
    Autoantigen NGP-1 antibody; Autoantigen NGP1 antibody; DJ423B22.6 (novel nucleolar guanosine 5'-triphosphate binding protein antibody; FLJ40906 antibody; GNL2 antibody; Guanine nucleotide binding protein-like 2 (nucleolar) antibody; HUMAUANTIG antibody; NGP1 antibody; NOG2_HUMAN antibody; novel nucleolar guanosine 5'-triphosphate binding protein autoantigen antibody; nucleolar G-protein gene 1 antibody; Nucleolar GTP binding protein 2 antibody; Nucleolar GTP-binding protein 2 antibody; Nucleolar GTPase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Nucleolar GTP-binding protein 2 protein (1-731AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，GNL2 Antibody (CSB-PA618806LA01HU)，的標記方式是Non-conjugated。對于GNL2 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA618806LB01HU GNL2 Antibody, HRP conjugated ELISA
    FITC CSB-PA618806LC01HU GNL2 Antibody, FITC conjugated
    Biotin CSB-PA618806LD01HU GNL2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels.
  • 基因功能參考文獻：
    1. NGP-1 promotes cell cycle progression through the activation of the p53/p21(Cip-1/Waf1) pathway. PMID: 26203195
    2. GNL2 and SEC13 are required for nonsense-mediated mRNA decay pathway in human cells. PMID: 25452588
  • 亞細胞定位：
    Nucleus, nucleolus.
  • 蛋白家族：
    TRAFAC class YlqF/YawG GTPase family, NOG2 subfamily
  • 組織特異性：
    Widely expressed, with the highest expression level in testis.
  • 數據庫鏈接：

    HGNC: 29925

    OMIM: 609365

    KEGG: hsa:29889

    STRING: 9606.ENSP00000362153

    UniGene: Hs.75528



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