在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GAS1 Antibody

  • 中文名稱:
    GAS1兔多克隆抗體
  • 貨號:
    CSB-PA009264LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: SH-SY5Y whole cell lysate, 293 whole cell lysate
      All lanes: GAS1 antibody at 3.2µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 36 kDa
      Observed band size: 36 kDa
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA009264LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA009264LA01HU at dilution of 1:100
    • Immunofluorescence staining of Hela cells with CSB-PA009264LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GAS1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    GAS-1 antibody; Gas1 antibody; GAS1_HUMAN antibody; Growth arrest-specific protein 1 antibody; Growth-arrest-specific protein 1 precursor antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Growth arrest-specific protein 1 protein (248-318AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,GAS1 Antibody (CSB-PA009264LA01HU),的標記方式是Non-conjugated。對于GAS1 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA009264LB01HU GAS1 Antibody, HRP conjugated ELISA
    FITC CSB-PA009264LC01HU GAS1 Antibody, FITC conjugated
    Biotin CSB-PA009264LD01HU GAS1 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
  • 基因功能參考文獻:
    1. Studies establish Gas1 as a negative regulator in colorectal cancer. PMID: 27401611
    2. These results demonstrated that miR-184 and the GAS1/Akt pathway may be a potential therapeutic target for intervertebral disc degeneration. PMID: 26805687
    3. WT1 modulates Akt/JNK signaling pathway mediated autophagy by controlling the expression of growth arrest-specific 1 (Gas1). PMID: 27453337
    4. Downregulation of GAS1 is associated with clear cell renal cell carcinoma. PMID: 28184927
    5. the synergistic effect of Gas1 inhibition and GDNF against glutamate-induced cell injury in human SH-SY5Y neuroblastoma cells, is reported. PMID: 26215053
    6. solutions structure and biophysical characterization of the multifaceted signalling effector protein growth arrest specific-1 PMID: 25888394
    7. This review summarizes the structure of Gas1 and molecular mechanism of action during embryonic development and cellular functions. PMID: 25429664
    8. GAS1 is a novel endogenous inhibitor of glomerular mesangial cell proliferation. PMID: 23254899
    9. Growth arrest-specific gene 1 is downregulated and inhibits tumor growth in gastric cancer. PMID: 22846196
    10. GAS1 induced the activity of caspase-3 and resulting in apoptosis of the cells. PMID: 22311470
    11. Interference of endoplasmic reticulum to Golgi transport increased immature amyloid beta protein precursor accumulation upon Gas1 expression in lipid raft fractions. PMID: 21971401
    12. we demonstrate that sequence variants in GAS1 can impair its physical interaction with SHH, suggesting a decrease in the SHH downstream signaling cascade as a pathogenic mechanism of disease. PMID: 21842183
    13. Gas1 is a novel APP-interacting protein involved in the control of APP maturation and processing. PMID: 21357679
    14. Growth arrest-specific gene 1 contributes to predicting metastasis or recurrence in stage II and III colorectal cancer. PMID: 21111449
    15. GAS1 could be considered a candidate locus for one of the types of human holoprosencephaly. PMID: 20583177
    16. Gas1 is related to the GDNF alpha receptors and regulates Ret signaling PMID: 16551639
    17. This review considers the possible involvement of GAS1 in genetic diseases, stem cell renewal, and cancer growth through its cooperative activity with Hedgehog (HH) growth factor and the HH receptor. PMID: 17726382
    18. Gas1 is a molecule involved in cell arrest that can induce apoptosis when over-expressed in different cell lines. PMID: 18394855
    19. Gas1 has all the expected properties of a melanoma tumor suppressor: suppression of metastasis in a spontaneous metastasis assay, promotion of apoptosis following dissemination of cells to secondary sites, and down-regulation in human melanoma metastasis. PMID: 18981472
    20. Results present evidence demonstrating that Gas1 exerts its effects inhibiting cell growth and inducing apoptosis of glioma cells in the absence of Shh. PMID: 19460624
    21. Results suggest that GAS1 might be a target to overcome multidrug resistance and provide a novel approach to identifying candidate genes that suppress chemoresistance of gastric cancers. PMID: 19638344
    22. GAS1 is preferentially expressed by human bulge cells, compared to differentiated hair follicle keratinocytes PMID: 20050020

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 數據庫鏈接:

    HGNC: 4165

    OMIM: 139185

    KEGG: hsa:2619

    STRING: 9606.ENSP00000298743

    UniGene: Hs.65029



主站蜘蛛池模板: 无码三级av电影在线观看| 西西人体444www高清大胆| 亚洲国产成人一区二区三区| 内射人妻少妇无码一本一道| 成人永久免费网站在线观看| 国产欧美va欧美va香蕉在| 亚洲久热中文字幕在线| 久久久国产精品va麻豆| 夜色爽爽影院18禁妓女影院| 国产麻豆剧果冻传媒白晶晶| 成人性生交大片免费看视频app| 国产成人av无码精品天堂| 国产精品国产三级国av| 亚洲日本精品国产一区vr| 亚洲精品黑牛一区二区三区| 国产对白老熟女正在播放| 日韩欧美中文字幕在线三区| 成人爽a毛片免费看| 久久精品亚洲综合专区 | 午夜理论片yy6080私人影院| 欧美xxxx做受欧美| 一二三四视频社区在线播放中国| 制服丝袜有码中文字幕在线| 狠狠色丁香久久综合婷婷| 成人免费无码大片a毛片抽搐色欲| 99精品国产兔费观看久久99| 无码成人片在线播放| 久久99精品久久久久久蜜芽 | 久久天天躁狠狠躁夜夜躁app| 亚洲国产av无码精品| 久久久久有精品国产麻豆| 国产aⅴ爽av久久久久久| 婷婷五月综合色中文字幕| 天堂www中文在线资源| 成人aa免费视频在线播放| 久久99国产综合精品女同| 色一情一乱一乱一区99av白浆| 久久精品动漫一区二区三区| 99热国产这里只有精品9| 国产成人av在线影院无毒| 国产成人精品亚洲日本在线|