在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GAS1 Antibody, Biotin conjugated

  • 中文名稱:
    GAS1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA009264LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GAS1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    GAS-1 antibody; Gas1 antibody; GAS1_HUMAN antibody; Growth arrest-specific protein 1 antibody; Growth-arrest-specific protein 1 precursor antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Growth arrest-specific protein 1 protein (248-318AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
  • 基因功能參考文獻:
    1. Studies establish Gas1 as a negative regulator in colorectal cancer. PMID: 27401611
    2. These results demonstrated that miR-184 and the GAS1/Akt pathway may be a potential therapeutic target for intervertebral disc degeneration. PMID: 26805687
    3. WT1 modulates Akt/JNK signaling pathway mediated autophagy by controlling the expression of growth arrest-specific 1 (Gas1). PMID: 27453337
    4. Downregulation of GAS1 is associated with clear cell renal cell carcinoma. PMID: 28184927
    5. the synergistic effect of Gas1 inhibition and GDNF against glutamate-induced cell injury in human SH-SY5Y neuroblastoma cells, is reported. PMID: 26215053
    6. solutions structure and biophysical characterization of the multifaceted signalling effector protein growth arrest specific-1 PMID: 25888394
    7. This review summarizes the structure of Gas1 and molecular mechanism of action during embryonic development and cellular functions. PMID: 25429664
    8. GAS1 is a novel endogenous inhibitor of glomerular mesangial cell proliferation. PMID: 23254899
    9. Growth arrest-specific gene 1 is downregulated and inhibits tumor growth in gastric cancer. PMID: 22846196
    10. GAS1 induced the activity of caspase-3 and resulting in apoptosis of the cells. PMID: 22311470
    11. Interference of endoplasmic reticulum to Golgi transport increased immature amyloid beta protein precursor accumulation upon Gas1 expression in lipid raft fractions. PMID: 21971401
    12. we demonstrate that sequence variants in GAS1 can impair its physical interaction with SHH, suggesting a decrease in the SHH downstream signaling cascade as a pathogenic mechanism of disease. PMID: 21842183
    13. Gas1 is a novel APP-interacting protein involved in the control of APP maturation and processing. PMID: 21357679
    14. Growth arrest-specific gene 1 contributes to predicting metastasis or recurrence in stage II and III colorectal cancer. PMID: 21111449
    15. GAS1 could be considered a candidate locus for one of the types of human holoprosencephaly. PMID: 20583177
    16. Gas1 is related to the GDNF alpha receptors and regulates Ret signaling PMID: 16551639
    17. This review considers the possible involvement of GAS1 in genetic diseases, stem cell renewal, and cancer growth through its cooperative activity with Hedgehog (HH) growth factor and the HH receptor. PMID: 17726382
    18. Gas1 is a molecule involved in cell arrest that can induce apoptosis when over-expressed in different cell lines. PMID: 18394855
    19. Gas1 has all the expected properties of a melanoma tumor suppressor: suppression of metastasis in a spontaneous metastasis assay, promotion of apoptosis following dissemination of cells to secondary sites, and down-regulation in human melanoma metastasis. PMID: 18981472
    20. Results present evidence demonstrating that Gas1 exerts its effects inhibiting cell growth and inducing apoptosis of glioma cells in the absence of Shh. PMID: 19460624
    21. Results suggest that GAS1 might be a target to overcome multidrug resistance and provide a novel approach to identifying candidate genes that suppress chemoresistance of gastric cancers. PMID: 19638344
    22. GAS1 is preferentially expressed by human bulge cells, compared to differentiated hair follicle keratinocytes PMID: 20050020

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 數據庫鏈接:

    HGNC: 4165

    OMIM: 139185

    KEGG: hsa:2619

    STRING: 9606.ENSP00000298743

    UniGene: Hs.65029



主站蜘蛛池模板: 男人的好看免费观看在线视频| 中国女人大白屁股ass| 国产精品福利视频萌白酱| 国产亚洲精品久久久久久无| 日本高清二区视频久二区| 吃奶呻吟张开双腿做受在线播放| 女人被爽到高潮视频免费国产| 亚洲裸男gv网站| 无码人妻aⅴ一区二区三区| 另类内射国产在线| 波多野42部无码喷潮在线| 日韩成人无码毛片一区二区| 久久成人国产精品无码| 男人的天堂2018无码| 久久久精品人妻无码专区不卡| 國产一二三内射在线看片| 人人妻人人妻人人片av| 97视频精品全国免费观看| 欧美人与禽zozzo性伦交| 国产婷婷综合在线视频| 毛片内射久久久一区| 国产麻豆md传媒视频| 四川少妇被弄到高潮| 老汉色老汉首页a亚洲| 男女啪啪永久免费网站| 亚洲国产精品久久精品| 黄瓜视频在线观看| 成人午夜亚洲精品无码区毛片| 老汉老妇姓交视频| 国产激情高中生呻吟视频| 久久婷婷国产综合精品| 亚洲精品久久7777777| 亚洲综合色婷婷七月丁香| 日产乱码一二三区别免费麻豆| 亚洲伊人成综合网2222| 欧美牲交a欧牲交aⅴ久久| av人摸人人人澡人人超碰小说| 亚洲精品一区二区三区麻豆| 精品视频在线观自拍自拍| 人人爽人人片人人片av| 一区二区三区人妻无码|