在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GAS1 Antibody, FITC conjugated

GAS1 Antibody, FITC conjugated

  • 中文名稱：
    GAS1兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA009264LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GAS1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    GAS-1 antibody; Gas1 antibody; GAS1_HUMAN antibody; Growth arrest-specific protein 1 antibody; Growth-arrest-specific protein 1 precursor antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Growth arrest-specific protein 1 protein (248-318AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
  • 基因功能參考文獻：
    1. Studies establish Gas1 as a negative regulator in colorectal cancer. PMID: 27401611
    2. These results demonstrated that miR-184 and the GAS1/Akt pathway may be a potential therapeutic target for intervertebral disc degeneration. PMID: 26805687
    3. WT1 modulates Akt/JNK signaling pathway mediated autophagy by controlling the expression of growth arrest-specific 1 (Gas1). PMID: 27453337
    4. Downregulation of GAS1 is associated with clear cell renal cell carcinoma. PMID: 28184927
    5. the synergistic effect of Gas1 inhibition and GDNF against glutamate-induced cell injury in human SH-SY5Y neuroblastoma cells, is reported. PMID: 26215053
    6. solutions structure and biophysical characterization of the multifaceted signalling effector protein growth arrest specific-1 PMID: 25888394
    7. This review summarizes the structure of Gas1 and molecular mechanism of action during embryonic development and cellular functions. PMID: 25429664
    8. GAS1 is a novel endogenous inhibitor of glomerular mesangial cell proliferation. PMID: 23254899
    9. Growth arrest-specific gene 1 is downregulated and inhibits tumor growth in gastric cancer. PMID: 22846196
    10. GAS1 induced the activity of caspase-3 and resulting in apoptosis of the cells. PMID: 22311470
    11. Interference of endoplasmic reticulum to Golgi transport increased immature amyloid beta protein precursor accumulation upon Gas1 expression in lipid raft fractions. PMID: 21971401
    12. we demonstrate that sequence variants in GAS1 can impair its physical interaction with SHH, suggesting a decrease in the SHH downstream signaling cascade as a pathogenic mechanism of disease. PMID: 21842183
    13. Gas1 is a novel APP-interacting protein involved in the control of APP maturation and processing. PMID: 21357679
    14. Growth arrest-specific gene 1 contributes to predicting metastasis or recurrence in stage II and III colorectal cancer. PMID: 21111449
    15. GAS1 could be considered a candidate locus for one of the types of human holoprosencephaly. PMID: 20583177
    16. Gas1 is related to the GDNF alpha receptors and regulates Ret signaling PMID: 16551639
    17. This review considers the possible involvement of GAS1 in genetic diseases, stem cell renewal, and cancer growth through its cooperative activity with Hedgehog (HH) growth factor and the HH receptor. PMID: 17726382
    18. Gas1 is a molecule involved in cell arrest that can induce apoptosis when over-expressed in different cell lines. PMID: 18394855
    19. Gas1 has all the expected properties of a melanoma tumor suppressor: suppression of metastasis in a spontaneous metastasis assay, promotion of apoptosis following dissemination of cells to secondary sites, and down-regulation in human melanoma metastasis. PMID: 18981472
    20. Results present evidence demonstrating that Gas1 exerts its effects inhibiting cell growth and inducing apoptosis of glioma cells in the absence of Shh. PMID: 19460624
    21. Results suggest that GAS1 might be a target to overcome multidrug resistance and provide a novel approach to identifying candidate genes that suppress chemoresistance of gastric cancers. PMID: 19638344
    22. GAS1 is preferentially expressed by human bulge cells, compared to differentiated hair follicle keratinocytes PMID: 20050020

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4165

    OMIM: 139185

    KEGG: hsa:2619

    STRING: 9606.ENSP00000298743

    UniGene: Hs.65029



主站蜘蛛池模板： 亚洲成在人线av无码| 欧美熟妇性xxx交潮喷| 亚洲日本va中文字幕久久| 日韩毛片在线视频x| 无修无码h里番在线播放网站| 少妇性荡欲视频| 偷妻之寂寞难耐2中文字幕| 特级精品毛片免费观看| 人与动人物xxxx毛片人与狍 | 国产精品992tv在线观看| 人禽伦免费交视频播放| 欧美日韩国产精品自在自线| 色8激情欧美成人久久综合电影| 猫咪免费人成网站在线观看| 高清视频在线观看一区二区三区| 和岳每晚弄的高潮嗷嗷叫视频| 蜜桃av久久久一区二区三区麻豆| 亚洲日韩国产一区二区三区在线 | av无码午夜福利一区二区三区| 欧美精品在线观看| 国产精品日本一区二区在线播放| 欧洲极品无码一区二区三区| 97精品尹人久久大香线蕉| 午夜影视免费| 香蕉人妻av久久久久天天| 欧美亚洲色aⅴ大片| 国产三级a三级三级| 亚洲无线码在线一区观看| 亚洲国产成人久久综合电影| 欧美高清大屁股xxxxx| 性开放的女人aaa片| 麻豆国产va免费精品高清在线| 精品久久久无码中文字幕一丶| 中文字幕乱码免费| 国产 麻豆 日韩 欧美 久久| 久久综合少妇11p| 亚洲精品国产一区二区的区别| 国内老熟妇对白hdxxxx| 饥渴少妇做私密保健视频| 国产很色很黄很大爽的视频| 天天摸夜夜摸夜夜狠狠摸|