在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GAP43 Antibody

  • 中文名稱:
    GAP43兔多克隆抗體
  • 貨號:
    CSB-PA000387
  • 規格:
    ¥1090
  • 圖片:
    • Western blot analysis of 1) Hela, 2) Mouse Brain, 3) Rat Brain tissue, diluted at 1:3000.
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    GAP43
  • 別名:
    Axonal membrane protein GAP 43 antibody; Axonal membrane protein GAP-43 antibody; B 50 antibody; Calmodulin binding protein P 57 antibody; F1 antibody; GAP 43 antibody; GAP43 antibody; Growth Associated Protein 43 antibody; Growth-associated protein 43 antibody; Nerve Growth Related Peptide antibody; Nerve growth related peptide GAP43 antibody; NEUM_HUMAN antibody; Neural phosphoprotein B 50 antibody; Neural phosphoprotein B-50 antibody; Neuromodulin antibody; Neuron growth associated protein 43 antibody; PP46 antibody; Protein F1 antibody; QtrA-11580 antibody; QtrA-13071 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Recombinant Protein
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-3000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
  • 基因功能參考文獻:
    1. We found an increased expression of Nestin and GAP43 (growth associated protein 43) in treated cells. In conclusion, Periodontal ligament mesenchymal stem cells (hPDLSCs) treated with Moringin and Cannabidiol showed an improved survival capacity and neuronal differentiation potential PMID: 30096889
    2. The expression pattern of the regeneration-associated protein GAP-43 suggested a lower regenerative capacity in nigral dopaminergic neurons of Parkinson disease patients. PMID: 26748453
    3. Findings show high level of both YKL-40 and GAP-43 in CSF of older women with suicidal ideation which suggest that a disrupted synaptic glial functioning and inflammation may be related to the aetiology of suicidal ideation in older adults. PMID: 28211584
    4. associations of neuromodulin and neurogranin to Alzheimer's disease PMID: 27604409
    5. Copy-number variations are enriched for GAP43 and other neurodevelopmental genes in children with developmental coordination disorder. PMID: 27489308
    6. Downregulation of GAP43 promotes gliomas. PMID: 27495233
    7. The peripheral neuropathies lead to an initial increase in GAP-43 gene expression as a potential mechanism of regeneration, which is not sustained in neuropathies of long duration. PMID: 26071889
    8. Results show that PKC-dependent phosphorylation of GAP43 plays a critical role in regulating postsynaptic gephyrin aggregation in developing GABAergic synapses. PMID: 25755278
    9. increased expression of TH and GAP43 might be a molecular mechanism for left atrial myoelectricity remodeling of aging atrial fibrillation patients, which might be potential therapeutic targets of atrial fibrillation. PMID: 24301786
    10. GAP43 is seemingly a highly sensitive marker for peripheral nerve sheath tumors PMID: 23887302
    11. The results showed that the decreased GAP-43 levels induced by glutamate could be partially reversed by the presence of NRG-1beta PMID: 23524246
    12. Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43 PMID: 23396970
    13. immunostaning for GAP-43 was relatively similar in ganglionic versus aganglionic colon. PMID: 23153097
    14. Impaired regeneration of intra-epidermal C fibers in the early stages of type 2 diabetes mellitus, as indicated by GAP-43 expression, might be a marker of incipient diabetic neuropathy. PMID: 22209024
    15. The results of this study supported to the hypothesis of multiple rare mutations in schizophrenia, and it provides genetic clues that indicate the involvement of GAP-43 in this disorder. PMID: 22138049
    16. Through MEK/ERK pathway, S1P stimulates GAP43 transcription with increased binding of C/EBPbeta to the 5'-promoter PMID: 21769916
    17. Results demonstrate that APT-2 is the protein thioesterase involved in the acylation/deacylation cycle operating in GAP-43 subcellular distribution. PMID: 21152083
    18. Results indicate that there is no strong and direct interaction between POP and GAP43 at physiological conditions. PMID: 20869470
    19. Around 1 month post lesion, degeneration at the cochlear nuclei progressively disappeared and a relevant GAP-43 expression was found. PMID: 19593683
    20. chemical analysis of fatty acylated species in GAP43 PMID: 12105219
    21. In the dermis, there were fewer GAP-43 nerve fibers than PGP 9.5 fibers, whereas in the epidermis the numbers were equal. Only some Merkel cells and Meissner corpuscles were GAP-43-immunoreactive. PMID: 12704705
    22. Data show that GAP43 acts as an osmosensory protein that augments internal calcium in response to hypotonicity. PMID: 12805215
    23. Schizophrenia had significant decreases in GAP-43 immunoreactivity in the hilus (p<0.05, paired t-test) and inner molecular layer (p<0.05, paired t-test) but not in the outer molecular layer. In the same tissues. PMID: 15694236
    24. Growth-associated protein 43, a marker of neural outgrowth and regeneration, is expressed in endometriosis-associated nerve fibers but not in existing peritoneal nerves. PMID: 17412328
    25. HuD plays a role in the post-transcriptional control of GAP-43 mRNA PMID: 17577668
    26. Data show that functional cooperation between TrkA and p75(NTR) accelerates neuronal differentiation by increased transcription of GAP-43 and p21(CIP/WAF) genes via ERK1/2 and AP-1 activities. PMID: 17619016

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Cell projection, filopodium membrane; Peripheral membrane protein. Perikaryon. Cell projection, dendrite. Cell projection, axon. Cytoplasm.
  • 蛋白家族:
    Neuromodulin family
  • 數據庫鏈接:

    HGNC: 4140

    OMIM: 162060

    KEGG: hsa:2596

    STRING: 9606.ENSP00000377372

    UniGene: Hs.134974



主站蜘蛛池模板: 亚洲暴爽av天天爽日日碰| 色婷婷狠狠97成为人免费| 亚洲成在人网站无码天堂 | 国产亚洲综合久久系列| 国产作爱视频免费播放| 亚洲午夜成人av电影| 伊人色综合一区二区三区| 高潮毛片无遮挡高清视频播放| 欧美一道本一区二区三区| 中美日韩毛片免费播放| 特黄aaaaaaa片免费视频| 国产女人高潮叫床视频| 337p西西人体大胆瓣开下部| 日韩综合亚洲色在线影院| 蜜桃麻豆www久久国产sex| 亚洲老妈激情一区二区三区| 五月婷婷开心中文字幕| 国产超碰人人爱被ios解锁| 五月丁香啪啪激情综合色九色| 潮喷无码正在播放| 男人和女人做爽爽视频| 午夜射精日本三级| 国产艳妇av在线出轨| 无码中出人妻中文字幕av | 亚洲精品无码不卡在线播放he| 国产 | 欧洲野花视频天堂视频p| 在办公室被c到呻吟的动态图| 99精品视频在线观看| 亚洲毛片无码不卡av在线播放| 久久九九精品国产免费看小说 | 热の综合热の国产热の潮在线| 亚洲人亚洲人成电影网站色| 无码aⅴ精品一区二区三区浪潮| 波多野结衣av一区二区全免费观看| 水蜜桃精品一二三| 久久精品亚洲综合专区| 日日摸天天爽天天爽视频| 欧美国产日韩a在线视频| 夜夜澡人摸人人添人人看| 国产成人青青久久大片| 日韩精品一区二区在线观看|