在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GAP43 (Ab-41) Antibody

  • 中文名稱:
    GAP43 (Ab-41)兔多克隆抗體
  • 貨號:
    CSB-PA249056
  • 規格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from mouse brain tissue using GAP43(Ab-41) Antibody and the same antibody preincubated with blocking peptide.
    • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using GAP43(Ab-41) Antibody(left) or the same antibody preincubated with blocking peptide(right).
    • Immunofluorescence staining of methanol-fixed Hela cells using GAP43(Ab-41) Antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GAP43 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GAP43
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Peptide sequence around aa.38~43 (Q-A-S-F-R) derived from Human GAP43.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC,IF
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:1000
    IHC 1:50-1:200
    IF 1:100-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
  • 基因功能參考文獻:
    1. We found an increased expression of Nestin and GAP43 (growth associated protein 43) in treated cells. In conclusion, Periodontal ligament mesenchymal stem cells (hPDLSCs) treated with Moringin and Cannabidiol showed an improved survival capacity and neuronal differentiation potential PMID: 30096889
    2. The expression pattern of the regeneration-associated protein GAP-43 suggested a lower regenerative capacity in nigral dopaminergic neurons of Parkinson disease patients. PMID: 26748453
    3. Findings show high level of both YKL-40 and GAP-43 in CSF of older women with suicidal ideation which suggest that a disrupted synaptic glial functioning and inflammation may be related to the aetiology of suicidal ideation in older adults. PMID: 28211584
    4. associations of neuromodulin and neurogranin to Alzheimer's disease PMID: 27604409
    5. Copy-number variations are enriched for GAP43 and other neurodevelopmental genes in children with developmental coordination disorder. PMID: 27489308
    6. Downregulation of GAP43 promotes gliomas. PMID: 27495233
    7. The peripheral neuropathies lead to an initial increase in GAP-43 gene expression as a potential mechanism of regeneration, which is not sustained in neuropathies of long duration. PMID: 26071889
    8. Results show that PKC-dependent phosphorylation of GAP43 plays a critical role in regulating postsynaptic gephyrin aggregation in developing GABAergic synapses. PMID: 25755278
    9. increased expression of TH and GAP43 might be a molecular mechanism for left atrial myoelectricity remodeling of aging atrial fibrillation patients, which might be potential therapeutic targets of atrial fibrillation. PMID: 24301786
    10. GAP43 is seemingly a highly sensitive marker for peripheral nerve sheath tumors PMID: 23887302
    11. The results showed that the decreased GAP-43 levels induced by glutamate could be partially reversed by the presence of NRG-1beta PMID: 23524246
    12. Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43 PMID: 23396970
    13. immunostaning for GAP-43 was relatively similar in ganglionic versus aganglionic colon. PMID: 23153097
    14. Impaired regeneration of intra-epidermal C fibers in the early stages of type 2 diabetes mellitus, as indicated by GAP-43 expression, might be a marker of incipient diabetic neuropathy. PMID: 22209024
    15. The results of this study supported to the hypothesis of multiple rare mutations in schizophrenia, and it provides genetic clues that indicate the involvement of GAP-43 in this disorder. PMID: 22138049
    16. Through MEK/ERK pathway, S1P stimulates GAP43 transcription with increased binding of C/EBPbeta to the 5'-promoter PMID: 21769916
    17. Results demonstrate that APT-2 is the protein thioesterase involved in the acylation/deacylation cycle operating in GAP-43 subcellular distribution. PMID: 21152083
    18. Results indicate that there is no strong and direct interaction between POP and GAP43 at physiological conditions. PMID: 20869470
    19. Around 1 month post lesion, degeneration at the cochlear nuclei progressively disappeared and a relevant GAP-43 expression was found. PMID: 19593683
    20. chemical analysis of fatty acylated species in GAP43 PMID: 12105219
    21. In the dermis, there were fewer GAP-43 nerve fibers than PGP 9.5 fibers, whereas in the epidermis the numbers were equal. Only some Merkel cells and Meissner corpuscles were GAP-43-immunoreactive. PMID: 12704705
    22. Data show that GAP43 acts as an osmosensory protein that augments internal calcium in response to hypotonicity. PMID: 12805215
    23. Schizophrenia had significant decreases in GAP-43 immunoreactivity in the hilus (p<0.05, paired t-test) and inner molecular layer (p<0.05, paired t-test) but not in the outer molecular layer. In the same tissues. PMID: 15694236
    24. Growth-associated protein 43, a marker of neural outgrowth and regeneration, is expressed in endometriosis-associated nerve fibers but not in existing peritoneal nerves. PMID: 17412328
    25. HuD plays a role in the post-transcriptional control of GAP-43 mRNA PMID: 17577668
    26. Data show that functional cooperation between TrkA and p75(NTR) accelerates neuronal differentiation by increased transcription of GAP-43 and p21(CIP/WAF) genes via ERK1/2 and AP-1 activities. PMID: 17619016

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Cell projection, filopodium membrane; Peripheral membrane protein. Perikaryon. Cell projection, dendrite. Cell projection, axon. Cytoplasm.
  • 蛋白家族:
    Neuromodulin family
  • 數據庫鏈接:

    HGNC: 4140

    OMIM: 162060

    KEGG: hsa:2596

    STRING: 9606.ENSP00000377372

    UniGene: Hs.134974



主站蜘蛛池模板: 九九久久精品国产波多野结衣| 欧美日韩精品无码一本二本三本色 | 国产人在线成免费视频| 特黄aaaaaaa片免费视频| 蜜桃视频一区二区在线观看| 日产一区日产2区| 国产精品无码综合区| 欧美亚洲国产第一精品久久| 亚洲男人天堂| 成人欧美一区二区三区黑人| 国内揄拍国内精品对白86| 99久e在线精品视频在线| 精品国产三级a∨在线欧美| 欧美xxxx做受欧美| 蜜桃av久久久一区二区三区麻豆 | 国产亚洲精品第一综合另类灬| 美女露出奶头扒开尿口视频直播| 色综亚洲国产vv在线观看| 国产亚洲美女精品久久久| 精品偷拍被偷拍在线观看| 成人国产精品秘片多多| 荫蒂被男人添的好舒服爽免费视频| 日韩在线一区二区三区免费视频| 久久精品成人免费观看97| 国产精品视频二区不卡| 国产精品嫩草影院av| 电影内射视频免费观看| 国产97色在线 | 欧洲| 正在播放老肥熟妇露脸| 亚洲va中文字幕无码久久| 99这里有精品视频视频| 久久天天躁狠狠躁夜夜2020一 | 精品一区二区三区无码免费直播| 韩国三级hd中文字幕| 少妇被又大又粗下爽a片| 无码人妻一区二区三区免费手机 | 国产精品无码久久av| 国产好大好硬好爽免费不卡| 国产av丝袜一区二区三区| 三个男吃我奶头一边一个视频| 国产三区在线成人av|