在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GAP43 Antibody

  • 中文名稱:
    GAP43兔多克隆抗體
  • 貨號:
    CSB-PA009231DSR1HU
  • 規格:
    ¥440
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GAP43 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GAP43
  • 別名:
    Axonal membrane protein GAP 43 antibody; Axonal membrane protein GAP-43 antibody; B 50 antibody; Calmodulin binding protein P 57 antibody; F1 antibody; GAP 43 antibody; GAP43 antibody; Growth Associated Protein 43 antibody; Growth-associated protein 43 antibody; Nerve Growth Related Peptide antibody; Nerve growth related peptide GAP43 antibody; NEUM_HUMAN antibody; Neural phosphoprotein B 50 antibody; Neural phosphoprotein B-50 antibody; Neuromodulin antibody; Neuron growth associated protein 43 antibody; PP46 antibody; Protein F1 antibody; QtrA-11580 antibody; QtrA-13071 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Neuromodulin protein (1-238AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
  • 基因功能參考文獻:
    1. We found an increased expression of Nestin and GAP43 (growth associated protein 43) in treated cells. In conclusion, Periodontal ligament mesenchymal stem cells (hPDLSCs) treated with Moringin and Cannabidiol showed an improved survival capacity and neuronal differentiation potential PMID: 30096889
    2. The expression pattern of the regeneration-associated protein GAP-43 suggested a lower regenerative capacity in nigral dopaminergic neurons of Parkinson disease patients. PMID: 26748453
    3. Findings show high level of both YKL-40 and GAP-43 in CSF of older women with suicidal ideation which suggest that a disrupted synaptic glial functioning and inflammation may be related to the aetiology of suicidal ideation in older adults. PMID: 28211584
    4. associations of neuromodulin and neurogranin to Alzheimer's disease PMID: 27604409
    5. Copy-number variations are enriched for GAP43 and other neurodevelopmental genes in children with developmental coordination disorder. PMID: 27489308
    6. Downregulation of GAP43 promotes gliomas. PMID: 27495233
    7. The peripheral neuropathies lead to an initial increase in GAP-43 gene expression as a potential mechanism of regeneration, which is not sustained in neuropathies of long duration. PMID: 26071889
    8. Results show that PKC-dependent phosphorylation of GAP43 plays a critical role in regulating postsynaptic gephyrin aggregation in developing GABAergic synapses. PMID: 25755278
    9. increased expression of TH and GAP43 might be a molecular mechanism for left atrial myoelectricity remodeling of aging atrial fibrillation patients, which might be potential therapeutic targets of atrial fibrillation. PMID: 24301786
    10. GAP43 is seemingly a highly sensitive marker for peripheral nerve sheath tumors PMID: 23887302
    11. The results showed that the decreased GAP-43 levels induced by glutamate could be partially reversed by the presence of NRG-1beta PMID: 23524246
    12. Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43 PMID: 23396970
    13. immunostaning for GAP-43 was relatively similar in ganglionic versus aganglionic colon. PMID: 23153097
    14. Impaired regeneration of intra-epidermal C fibers in the early stages of type 2 diabetes mellitus, as indicated by GAP-43 expression, might be a marker of incipient diabetic neuropathy. PMID: 22209024
    15. The results of this study supported to the hypothesis of multiple rare mutations in schizophrenia, and it provides genetic clues that indicate the involvement of GAP-43 in this disorder. PMID: 22138049
    16. Through MEK/ERK pathway, S1P stimulates GAP43 transcription with increased binding of C/EBPbeta to the 5'-promoter PMID: 21769916
    17. Results demonstrate that APT-2 is the protein thioesterase involved in the acylation/deacylation cycle operating in GAP-43 subcellular distribution. PMID: 21152083
    18. Results indicate that there is no strong and direct interaction between POP and GAP43 at physiological conditions. PMID: 20869470
    19. Around 1 month post lesion, degeneration at the cochlear nuclei progressively disappeared and a relevant GAP-43 expression was found. PMID: 19593683
    20. chemical analysis of fatty acylated species in GAP43 PMID: 12105219
    21. In the dermis, there were fewer GAP-43 nerve fibers than PGP 9.5 fibers, whereas in the epidermis the numbers were equal. Only some Merkel cells and Meissner corpuscles were GAP-43-immunoreactive. PMID: 12704705
    22. Data show that GAP43 acts as an osmosensory protein that augments internal calcium in response to hypotonicity. PMID: 12805215
    23. Schizophrenia had significant decreases in GAP-43 immunoreactivity in the hilus (p<0.05, paired t-test) and inner molecular layer (p<0.05, paired t-test) but not in the outer molecular layer. In the same tissues. PMID: 15694236
    24. Growth-associated protein 43, a marker of neural outgrowth and regeneration, is expressed in endometriosis-associated nerve fibers but not in existing peritoneal nerves. PMID: 17412328
    25. HuD plays a role in the post-transcriptional control of GAP-43 mRNA PMID: 17577668
    26. Data show that functional cooperation between TrkA and p75(NTR) accelerates neuronal differentiation by increased transcription of GAP-43 and p21(CIP/WAF) genes via ERK1/2 and AP-1 activities. PMID: 17619016

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Cell projection, filopodium membrane; Peripheral membrane protein. Perikaryon. Cell projection, dendrite. Cell projection, axon. Cytoplasm.
  • 蛋白家族:
    Neuromodulin family
  • 數據庫鏈接:

    HGNC: 4140

    OMIM: 162060

    KEGG: hsa:2596

    STRING: 9606.ENSP00000377372

    UniGene: Hs.134974



主站蜘蛛池模板: 国产乱子伦精品免费无码专区| 亚洲国产一区二区三区波多野结衣| 人人妻人人爽人人做夜欢视频| 国产亚洲精品久久久久小| 国产亚洲精品电影网站在线观看| 色yeye香蕉凹凸视频在线观看| 亚洲另类无码一区二区三区| 亚洲成色在线综合网站| 色欲色香天天天综合网站| 亚洲hdmi高清线| 内射国产内射夫妻免费频道| 精品久久久久久无码专区| 日本国产成人国产在线播放| 男女爽爽无遮挡午夜视频| 亚洲爆乳无码精品aaa片蜜桃| 国产精品videossex久久发布 | 欧美激情一区二区三区高清视频| 日本熟妇色高清免费视频| 蜜臀久久99精品久久久久久小说| 内射精品无码中文字幕| 一二三四免费观看在线视频中文版 | 在线观看高h无码黄动漫| 亚洲v天堂v手机在线| 亚洲中文无码永久免费| 99热这里只就有精品22| 亚洲国产精品无码久久一区二区| 性一交一乱一乱一视频 | 国产伦久视频免费观看视频| 老熟女 露脸 嗷嗷叫| 天天做av天天爱天天爽| 午夜一区二区亚洲福利| 国产亚洲精品一区二区三区| 在线观看无码不卡av中文| 无码精品人妻一区二区三区av | 亚洲中文在线精品国产| 久久午夜无码鲁丝片午夜精品| 亚洲精品v天堂中文字幕 | 亚洲欧美国产免费综合视频| 亚洲精品国产精品国自产观看| 免费人成网站在线观看不卡| 国产亚洲精品视觉盛宴|