在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GALR1 Antibody

  • 中文名稱:
    GALR1兔多克隆抗體
  • 貨號:
    CSB-PA009223LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: HepG2 whole cell lysate
      All lanes: GALR1 antibody at 2µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 39 kDa
      Observed band size: 39 kDa
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GALR1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    GALR1; GALNR; GALNR1; Galanin receptor type 1; GAL1-R; GALR-1
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Galanin receptor type 1 protein (293-349AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,GALR1 Antibody (CSB-PA009223LA01HU),的標記方式是Non-conjugated。對于GALR1 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA009223LB01HU GALR1 Antibody, HRP conjugated ELISA
    FITC CSB-PA009223LC01HU GALR1 Antibody, FITC conjugated
    Biotin CSB-PA009223LD01HU GALR1 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
  • 基因功能參考文獻:
    1. High methylation of GALR1 is associated with head and neck cancer. PMID: 27027429
    2. Study provides evidence that GAL and GALR1/2 genes were identified as aberrantly methylated in head and neck squamous cell carcinoma. PMID: 27685843
    3. The MOR-Gal1R heteromer can explain previous results showing antagonistic galanin-opioid interactions and offers a new therapeutic target for the treatment of opioid use disorder PMID: 28007761
    4. GAL and its receptors, GALR1 and GALR2, play a role in head and neck squamous cell carcinoma tumorigenesis PMID: 26572146
    5. Variants in genes for galanin (GAL) and its receptors (GALR1, GALR2, GALR3), despite their disparate genomic loci, conferred increased risk of depression and anxiety in people who experienced childhood adversity or recent negative life events. PMID: 24706871
    6. GALR1 methylation is associated with endometrial cancer. PMID: 23727823
    7. Moreover, we have identified a novel role for the GalR1/galanin receptor-ligand axis in chemoresistance, providing evidence to support its further evaluation as a potential therapeutic target and biomarker in colorectal cancer . PMID: 22859720
    8. Genetic variants in the GALR1 gene are associated with a protective effect in nicotine dependence. PMID: 21796100
    9. The results of this study suggested an association between variation at the GALR1 locus and baseline craving for tobacco in smokers seeking cessation treatment. PMID: 21430647
    10. it has been demonstrated that GalR1-5-HT1A receptors heteromerize. PMID: 20171159
    11. disregulation of galanin receptor 1 may lead to uncontrolled proliferation and neoplastic transformation PMID: 15767248
    12. The analyzed single nucleotide polymorphisms in GAL and GALR1 do not play major role in early onset obesity or dietary fat intake in obese children and adolescents. PMID: 15930442
    13. There was no effect of GALR1 on alcoholism risk. PMID: 17083333
    14. Data suggest that galanin stimulates cortisol secretion from human inner adrenocortical cells, acting through GAL-R1 coupled to the adenylate cyclase/PKA-dependent signaling cascade via a Ptx-sensitive Galpha protein. PMID: 17982695
    15. GalR1 is internalized via the clathrin-dependent, endocytic pathway and then, to a large extent, delivered to lysosomes for degradation through the lysosome-targeting signal YXXO PMID: 18385373
    16. GAL, coding for the neuropeptide galanin, and GALR1, a galanin receptor, were identified as candidate genes of oncogenesis in squamous cell carcinoma using a survey of parallel chromosomal alterations and gene expression studies in 10 SCC cell lines. PMID: 18973137
    17. GALR1 is a tumor suppressor gene in head and neck squamous cell carcinoma PMID: 19047085

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 數據庫鏈接:

    HGNC: 4132

    OMIM: 600377

    KEGG: hsa:2587

    STRING: 9606.ENSP00000299727

    UniGene: Hs.272191



主站蜘蛛池模板: 午夜精品国产精品大乳美女| 亚洲在av极品无码天堂手机版| 亚洲日韩片无码中文字幕| 日本成本人三级在线观看| 久久国产免费观看精品a片| 丰满妇女强制高潮18xxxx| 日日摸夜夜添夜夜添无码| 天堂中文8资源在线8| 亚洲综合狠狠丁香五月| 五月色婷婷丁香无码三级| 色五月丁香六月欧美综合| 18禁黄污吃奶免费看网站| 偷看农村妇女牲交| 饥渴丰满少妇大力进入| 亚洲一区精品无码色成人| 亚洲熟妇无码av不卡在线播放| 中文国产成人精品久久不卡| 国产99久久久久久免费看| 亚洲夜色噜噜av在线观看| 亚洲精品av一区在线观看 | 久久无码专区国产精品s| 国产爆乳无码视频在线观看| 波多野结av在线无码中文| 亚洲精品久久久久久中文传媒| 69精品丰满人妻无码视频a片| 综合图区亚洲另类偷窥| 夜夜添无码试看一区二区三区| 欧美性潮喷xxxxx免费视频看| 丰满女人又爽又紧又丰满| 日韩人妻无码制服丝袜视频| 中文字字幕在线乱码视频| 亚洲欧美另类精品二区| 无码一区二区三区亚洲人妻| 一二三区乱码不卡手机版| 免费人成网站在线视频| 天天摸天天做天天爽水多| 又黄又爽又猛的视频免费| 亚洲成av人片天堂网久久| 国产精品亚亚洲欧关中字幕 | 激情综合五月| 成年无码动漫av片在线观看羞羞|