在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GABARAPL1 Antibody

GABARAPL1 Antibody

  • 中文名稱：
    GABARAPL1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA009131GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    APG8 like antibody; APG8L antibody; ATG8 antibody; ATG8B antibody; ATG8L antibody; Early estrogen regulated protein antibody; Early estrogen-regulated protein antibody; GABA antibody; GABA(A) receptor associated protein like 1 antibody; GABA(A) receptor-associated protein-like 1 antibody; GABARAPL1 a antibody; GABARAPL1 antibody; Gamma aminobutyric acid receptor associated protein like 1 antibody; Gamma-aminobutyric acid receptor-associated protein-like 1 antibody; GBRL1_HUMAN antibody; GEC 1 antibody; GEC-1 antibody; GEC1 antibody; Glandular epithelial cell protein 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human GABARAPL1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover.
  • 基因功能參考文獻(xiàn)：
    1. these results indicate that miR-195 regulates cell proliferation, migration, angiogenesis and autophagy of hEPCs by targeting GABARAPL1 PMID: 27623937
    2. Our data demonstrated that a specific decrease of GABARAPL1 expression in breast cancers was associated with both DNA methylation and histone deacetylation and that CREB-1 recruitment on GABARAPL1 PMID: 26474850
    3. Androgen deprivation downregulates Gabarapl1 in an AR dependent manner, resulting in the increase of autophagy flux PMID: 26050226
    4. GABARAPL1 plays an important role in cell proliferation, invasion, and autophagic flux, as well as in mitochondrial homeostasis and cellular metabolic programs in a breast cancer cell line. PMID: 24879149
    5. Kaplan-Meier survival analysis showed a significant association between low GABARAPL1 expression and poor prognosis of HCC patients. PMID: 24647565
    6. Data demonstrate that HSP90 interacts and protects GABARAPL1 from its degradation by the proteasome. PMID: 22120110
    7. analysis of specific functions of GABARAPL1 [review] PMID: 21597319
    8. Atg8 interacting motif (AIM) in Stbd1 is necessary for GABARAPL1 binding. PMID: 21893048
    9. Results indicate that the presence of a tryptophan residue in the LIR motif increases the binding affinity of GABARAPL-1/NBR1-LIR complex. PMID: 21620860
    10. Gabarapl1 mRNA expression in breast tumours is a good indicator of the risk of recurrence, specifically in lymph nodes positive patients. PMID: 20197771
    11. GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor PMID: 16431922
    12. GEC1-kappa opioid receptor binding involves hydrophobic interactions: GEC1 has chaperone-like effect. PMID: 19001416
    13. Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis. PMID: 19549685

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle membrane; Lipid-anchor. Cytoplasm, cytoskeleton. Endoplasmic reticulum. Golgi apparatus.
  • 蛋白家族：
    ATG8 family
  • 組織特異性：
    Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine. In the brain, expression is particularly intense in motone
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4068

    OMIM: 607420

    KEGG: hsa:23710

    STRING: 9606.ENSP00000266458

    UniGene: Hs.524250



主站蜘蛛池模板： 无码中文字幕va精品影院| 久在线观看福利视频| 成年女人18级毛片毛片免费| 骚片av蜜桃精品一区| 曰批免费视频播放免费直播| 成人乱码一区二区三区av66| 99久久99久久久精品齐齐| 337p日本欧洲亚洲大胆| 午夜免费福利小电影| 欧美不卡无线在线一二三区观| 中国少妇videos呻吟| 蜜臀av性久久久久蜜臀aⅴ麻豆 | 久久久久人妻一区二区三区vr| 亚洲欧洲国产综合aⅴ无码| 色欲天天婬色婬香综合网| 少妇粉嫩小泬白浆流出| 蜜桃av色偷偷av老熟女 | 国产精品无码a∨果冻传媒| 国产真人作爱免费视频道歉| 国产午夜精品久久久久免费视| 妺妺窝人体色www看美女| 欧美色就是色| 午夜男女爽爽影院免费视频| 性色香蕉av久久久天天网| 人人人妻人人澡人人爽欧美一区| 亚洲啪啪综合av一区| 国产成人无码18禁午夜福利网址| 午夜性爽视频男人的天堂| 真人抽搐一进一出视频| 校园春色~综合网| 18禁亚洲深夜福利入口| 无码av专区丝袜专区| 草色噜噜噜av在线观看香蕉| 天天躁日日躁狠狠躁超碰97| 国产激情无码一区二区app| 99久久精品视香蕉蕉| 在厨房拨开内裤进入毛片| 国产边摸边吃奶边做爽视频| 日本欧美亚洲中文在线观看| 亚洲午夜无码久久久久软件| 国产亚洲精品一区二区三区|