在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GABARAPL1 Antibody, HRP conjugated

GABARAPL1 Antibody, HRP conjugated

  • 中文名稱(chēng)：
    GABARAPL1兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA861986LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) GABARAPL1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    APG8 like antibody; APG8L antibody; ATG8 antibody; ATG8B antibody; ATG8L antibody; Early estrogen regulated protein antibody; Early estrogen-regulated protein antibody; GABA antibody; GABA(A) receptor associated protein like 1 antibody; GABA(A) receptor-associated protein-like 1 antibody; GABARAPL1 a antibody; GABARAPL1 antibody; Gamma aminobutyric acid receptor associated protein like 1 antibody; Gamma-aminobutyric acid receptor-associated protein-like 1 antibody; GBRL1_HUMAN antibody; GEC 1 antibody; GEC-1 antibody; GEC1 antibody; Glandular epithelial cell protein 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Gamma-aminobutyric acid receptor-associated protein-like 1 protein (1-117AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover.
  • 基因功能參考文獻(xiàn)：
    1. these results indicate that miR-195 regulates cell proliferation, migration, angiogenesis and autophagy of hEPCs by targeting GABARAPL1 PMID: 27623937
    2. Our data demonstrated that a specific decrease of GABARAPL1 expression in breast cancers was associated with both DNA methylation and histone deacetylation and that CREB-1 recruitment on GABARAPL1 PMID: 26474850
    3. Androgen deprivation downregulates Gabarapl1 in an AR dependent manner, resulting in the increase of autophagy flux PMID: 26050226
    4. GABARAPL1 plays an important role in cell proliferation, invasion, and autophagic flux, as well as in mitochondrial homeostasis and cellular metabolic programs in a breast cancer cell line. PMID: 24879149
    5. Kaplan-Meier survival analysis showed a significant association between low GABARAPL1 expression and poor prognosis of HCC patients. PMID: 24647565
    6. Data demonstrate that HSP90 interacts and protects GABARAPL1 from its degradation by the proteasome. PMID: 22120110
    7. analysis of specific functions of GABARAPL1 [review] PMID: 21597319
    8. Atg8 interacting motif (AIM) in Stbd1 is necessary for GABARAPL1 binding. PMID: 21893048
    9. Results indicate that the presence of a tryptophan residue in the LIR motif increases the binding affinity of GABARAPL-1/NBR1-LIR complex. PMID: 21620860
    10. Gabarapl1 mRNA expression in breast tumours is a good indicator of the risk of recurrence, specifically in lymph nodes positive patients. PMID: 20197771
    11. GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor PMID: 16431922
    12. GEC1-kappa opioid receptor binding involves hydrophobic interactions: GEC1 has chaperone-like effect. PMID: 19001416
    13. Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis. PMID: 19549685

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle membrane; Lipid-anchor. Cytoplasm, cytoskeleton. Endoplasmic reticulum. Golgi apparatus.
  • 蛋白家族：
    ATG8 family
  • 組織特異性：
    Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine. In the brain, expression is particularly intense in motone
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 4068

    OMIM: 607420

    KEGG: hsa:23710

    STRING: 9606.ENSP00000266458

    UniGene: Hs.524250



主站蜘蛛池模板： 国产精品亚洲а∨无码播放不卡| 久久不见久久见免费影院www日本| 国产美女嘘嘘嘘嘘嘘| 人妻熟女一区二区aⅴ水野朝阳 | 精品国产三级在线观看| 五十路熟妇亲子交尾| 精品一区二区三区国产在线观看| 天堂av成年av影视| 极品白嫩的小少妇| 特级无码毛片免费视频尤物| 变态另类先锋影音| 人妻熟女一区二区aⅴ清水理纱| 黑人巨大精品欧美| 国产偷人妻精品一区二区在线| 亚洲国产日韩在线人成蜜芽| 和黑人邻居中文字幕在线| 顶级欧美熟妇xx| 大学生久久香蕉国产线看观看| 成 人影片 免费观看在线| 国产成人综合色就色综合| 伊人www22综合色| 亚洲va综合va国产产va中文| 亚洲国产美女久久久久| 国产精品久久久久无码av色戒| 国产精品无码永久免费不卡 | 男人的天堂在线视频 | 久久精品人人做人人综合| 久9视频这里只有精品| 疯狂做受xxxx高潮欧美日本| 国产国拍亚洲精品av| 性无码一区二区三区在线观看| 国产亚洲日韩欧美一区二区三区| 日本中文字幕人妻不卡dvd| 亚洲日韩成人无码不卡网站| 国产精品18久久久久久vr| 97久久久人妻一区精品| 国语对白刺激精品视频 | 全黄性性激高免费视频| 国产一区丝袜在线播放| 亚洲成成熟女人专区| 精品人妻伦九区久久aaa片|