在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FOSL2 Antibody

  • 中文名稱:
    FOSL2兔多克隆抗體
  • 貨號:
    CSB-PA008793ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: FOSL2 antibody at 8μg/ml
      Lane 1: MCF-7 whole cell lysate
      Lane 2: Jurkat whole cell lysate
      Lane 3: PC-3 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 36, 35, 32 kDa
      Observed band size: 36 kDa
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA008793ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA008793ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) FOSL2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    FLJ23306 antibody; Fos L2 antibody; FOS like antigen 2 antibody; Fos related antigen 2 antibody; Fos-related antigen 2 antibody; FosL 2 antibody; Fosl2 antibody; FOSL2_HUMAN antibody; FRA 2 antibody; FRA-2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Fos-related antigen 2 protein (187-326AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:200-1:1000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Controls osteoclast survival and size. As a dimer with JUN, activates LIF transcription. Activates CEBPB transcription in PGE2-activated osteoblasts.
  • 基因功能參考文獻:
    1. this study indicates the existence of an aberrant miR-124-3p/Fra-2 pathway that results in glioma aggressiveness PMID: 30243808
    2. Data provide evidence that FOSL2 is the target gene of miR-143 and negatively correlated with its expression. Down-regulation of FOSL2 seems to be a critical step in regulation of OS properties and the expression of miR-143 can inhibit the proliferation, migration and invasion of OS by reducing the expression of FOSL2. PMID: 29330462
    3. FOSL2 is a direct target of miR-597 in breast cancer cells. PMID: 28393251
    4. The binding and expression of c-Fos/Fra-2 increased as a function of severity of tongue lesions, yet selective participation of c-Jun appears to promote poor differentiation and aggressive tumorigenesis. PMID: 26581505
    5. FOSL2 facilitates TGF-beta1-induced migration by interaction with Smad3 in non-small cell lung cancer.FOSL2 positively regulates TGF-beta1 signalling . PMID: 25375657
    6. FRA2 is a STAT5 target gene regulated by IL-2 in human CD4 T cells. PMID: 24587342
    7. we show that the suppression was mediated, at least in part, by a suspension culture-driven decrease in the levels of two members of the AP1 transcription factor complex, c-Jun and Fra2 PMID: 23339184
    8. SOX4 is a direct target gene of FRA-2 and induces expression of HDAC8 in adult T-cell leukemia/lymphoma. PMID: 23482931
    9. This study suggests that Fra-2 transgenic mice as an animal model of systemic sclerosis-associated pulmonary arterial hypertension display main characteristic features of the human disease. PMID: 22523431
    10. results demonstrate the presence of a common oncogenic cascade initiated by FRA2/JUND in CCR4-expressing mature T-cell malignancies such as ATLL and CTCLs PMID: 22493372
    11. FOSL2 is a critical regulator of leptin expression in adipocytes PMID: 22326952
    12. Results suggest that Fra-2 protein may be more effective than ATF-2 protein in cyst formation originated from epithelial cells of dental follicles. PMID: 20675274
    13. These findings reveal a novel function of Fra-2/AP-1 as a positive regulator of bone and matrix formation in mice and humans. PMID: 20837772
    14. Fra-2 is overexpressed in SSc and acts as a novel downstream mediator of the profibrotic effects of TGFbeta and PDGF. PMID: 20039427
    15. Fra-2 overexpression is associated with a more aggressive tumor phenotype and is probably involved in breast cancer progression in vivo. PMID: 17393299
    16. aberrantly expressed Fra-2 in association with JunD may play a major role in CCR4 expression and oncogenesis in adult T-cell leukemia. PMID: 18071306
    17. Genes for Fra2, Id2, and CSF1-receptor are deregulated, regardless of whether the in anaplastic large cell lymphoma contains the t(2;5). PMID: 19321746
    18. Fra-2 transgenic natural killer (NK)T cells produce unusually high amounts of interleukin (IL)-2 and IL-4, and proliferate abnormally. PMID: 19620306
    19. Fra-2 is present in human systemic sclerosis and may contribute to the development of microvasculopathy by inducing endothelial cell apoptosis and by reducing endothelial cell migration and chemotaxis. PMID: 19933934

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    BZIP family, Fos subfamily
  • 數據庫鏈接:

    HGNC: 3798

    OMIM: 601575

    KEGG: hsa:2355

    STRING: 9606.ENSP00000264716

    UniGene: Hs.220971



主站蜘蛛池模板: 真人与拘做受免费视频| 亚洲已满18点击进入在线观看| 五月婷婷之综合缴情| 性中国妓女毛茸茸视频| 午夜亚洲精品久久一区二区| 中国产xxxxa片在线观看| 亚洲成a人片77777kkkk| 免费裸体黄网站18禁免费| 精品无码久久久久国产电影| 国产av天堂亚洲国产av麻豆| 成人精品天堂一区二区三区| 亚洲国产成人一区二区精品区| 欧美96在线 | 欧| 国产美女亚洲精品久久久| 99久久国产露脸精品竹菊传媒| 久久这里精品国产99丫e6| 精品国产乱码久久久久夜深人妻| 亚洲精品尤物av在线观看不卡 | 亚洲精品一区二区三区新线路 | 好男人www社区视频在线资源| 成人爽a毛片在线视频| 大伊香蕉精品一区视频在线 | 亚洲自偷自偷在线成人网址| 久久精品国产只有精品96| 果冻传媒18禁免费视频| 精品影片在线观看的网站| 国产在线视频精品视频| 亚洲欧美人成网站aaa| av大片在线无码免费| 午夜大片免费男女爽爽影院| 国产av麻豆mag剧集| 国内外精品激情刺激在线| 亚洲一卡2卡三卡4卡无卡下载| 伊人久久大香线蕉av五月天宝贝| 久久精品国产亚洲精品| 大肉大捧一进一出视频出来呀 | 日本高清熟妇老熟妇| 首页 国产 亚洲 丝袜图片区| 欧美黑人巨大videos精品| 西西人体www大胆高清| 欧美丰满肥婆videos |