在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FOSL2 Antibody

  • 中文名稱:
    FOSL2兔多克隆抗體
  • 貨號:
    CSB-PA008793HA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA008793HA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA008793HA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) FOSL2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    FLJ23306 antibody; Fos L2 antibody; FOS like antigen 2 antibody; Fos related antigen 2 antibody; Fos-related antigen 2 antibody; FosL 2 antibody; Fosl2 antibody; FOSL2_HUMAN antibody; FRA 2 antibody; FRA-2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Fos-related antigen 2 protein (1-326AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,FOSL2 Antibody (CSB-PA008793HA01HU),的標記方式是Non-conjugated。對于FOSL2 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA008793HB01HU FOSL2 Antibody, HRP conjugated ELISA
    FITC CSB-PA008793HC01HU FOSL2 Antibody, FITC conjugated
    Biotin CSB-PA008793HD01HU FOSL2 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Controls osteoclast survival and size. As a dimer with JUN, activates LIF transcription. Activates CEBPB transcription in PGE2-activated osteoblasts.
  • 基因功能參考文獻:
    1. this study indicates the existence of an aberrant miR-124-3p/Fra-2 pathway that results in glioma aggressiveness PMID: 30243808
    2. Data provide evidence that FOSL2 is the target gene of miR-143 and negatively correlated with its expression. Down-regulation of FOSL2 seems to be a critical step in regulation of OS properties and the expression of miR-143 can inhibit the proliferation, migration and invasion of OS by reducing the expression of FOSL2. PMID: 29330462
    3. FOSL2 is a direct target of miR-597 in breast cancer cells. PMID: 28393251
    4. The binding and expression of c-Fos/Fra-2 increased as a function of severity of tongue lesions, yet selective participation of c-Jun appears to promote poor differentiation and aggressive tumorigenesis. PMID: 26581505
    5. FOSL2 facilitates TGF-beta1-induced migration by interaction with Smad3 in non-small cell lung cancer.FOSL2 positively regulates TGF-beta1 signalling . PMID: 25375657
    6. FRA2 is a STAT5 target gene regulated by IL-2 in human CD4 T cells. PMID: 24587342
    7. we show that the suppression was mediated, at least in part, by a suspension culture-driven decrease in the levels of two members of the AP1 transcription factor complex, c-Jun and Fra2 PMID: 23339184
    8. SOX4 is a direct target gene of FRA-2 and induces expression of HDAC8 in adult T-cell leukemia/lymphoma. PMID: 23482931
    9. This study suggests that Fra-2 transgenic mice as an animal model of systemic sclerosis-associated pulmonary arterial hypertension display main characteristic features of the human disease. PMID: 22523431
    10. results demonstrate the presence of a common oncogenic cascade initiated by FRA2/JUND in CCR4-expressing mature T-cell malignancies such as ATLL and CTCLs PMID: 22493372
    11. FOSL2 is a critical regulator of leptin expression in adipocytes PMID: 22326952
    12. Results suggest that Fra-2 protein may be more effective than ATF-2 protein in cyst formation originated from epithelial cells of dental follicles. PMID: 20675274
    13. These findings reveal a novel function of Fra-2/AP-1 as a positive regulator of bone and matrix formation in mice and humans. PMID: 20837772
    14. Fra-2 is overexpressed in SSc and acts as a novel downstream mediator of the profibrotic effects of TGFbeta and PDGF. PMID: 20039427
    15. Fra-2 overexpression is associated with a more aggressive tumor phenotype and is probably involved in breast cancer progression in vivo. PMID: 17393299
    16. aberrantly expressed Fra-2 in association with JunD may play a major role in CCR4 expression and oncogenesis in adult T-cell leukemia. PMID: 18071306
    17. Genes for Fra2, Id2, and CSF1-receptor are deregulated, regardless of whether the in anaplastic large cell lymphoma contains the t(2;5). PMID: 19321746
    18. Fra-2 transgenic natural killer (NK)T cells produce unusually high amounts of interleukin (IL)-2 and IL-4, and proliferate abnormally. PMID: 19620306
    19. Fra-2 is present in human systemic sclerosis and may contribute to the development of microvasculopathy by inducing endothelial cell apoptosis and by reducing endothelial cell migration and chemotaxis. PMID: 19933934

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    BZIP family, Fos subfamily
  • 數據庫鏈接:

    HGNC: 3798

    OMIM: 601575

    KEGG: hsa:2355

    STRING: 9606.ENSP00000264716

    UniGene: Hs.220971



主站蜘蛛池模板: 国产av亚洲aⅴ一区二区| 亚洲欧美日本中文字不卡| 性欧美俄罗斯乱妇| 特级毛片a片久久久久久| 天天摸夜夜摸夜夜狠狠摸| 国产一区二区在线影院| 双乳被一左一右吃着动态图| 国产av一区二区精品久久凹凸| 西西4444www大胆无码| 日日躁夜夜躁狠狠躁| 免费国产高清毛不卡片基地| 欧美乱码卡一卡二卡三新区| 成人做受黄大片| 精品夜夜爽欧美毛片视频| 国产精品点击进入在线影院高清| 国产一区二区不卡在线看| 免费毛儿一区二区十八岁| 欧美丰满熟妇xxxx性大屁股| 少妇高清精品毛片在线视频| 亚洲精品久久国产精品浴池| 欧美野性肉体狂欢大派对| 国产成人无码av在线播放dvd| 无码av免费永久免费永久专区| 国产福利自产拍| 文中字幕一区二区三区视频播放 | 国产亚洲tv在线观看| 久久久久久人妻精品一区| 人妻大战黑人白浆狂泄| 国产精品国产三级国av麻豆| 在线天堂资源www在线污| 少妇人妻在线视频| 亚洲妓女综合网99| 狠狠色噜噜狠狠狠狠色综合久av| 国产制服丝袜欧美在线观看| 久久久久国产精品无码免费看| 四虎成人精品无码永久在线| 国产精品白丝av网站| 国产真人性做爰久久网站| 欧美老熟妇喷水| 久久久精品456亚洲影院| 极品人妻videosss人妻|