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  4. FBP2 Antibody

FBP2 Antibody

  • 中文名稱：
    FBP2兔多克隆抗體
  • 貨號：
    CSB-PA008460LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: MCF-7 whole cell lysate, Rat skeletal muscle tissue
      All lanes: FBP2 antibody at 3.5μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 37 kDa
      Observed band size: 37 kDa
    • Immunofluorescence staining of HepG2 cells with CSB-PA008460LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) FBP2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    6-bisphosphatase isozyme 2 antibody; 6-bisphosphate 1-phosphohydrolase 2 antibody; D fructose 1 6 bisphosphate 1 phosphohydrolase 2 antibody; D-fructose-1 antibody; F16P2_HUMAN antibody; FBP 2 antibody; fbp2 antibody; FBPase 2 antibody; FBPase antibody; fructose 1 6 bisphosphatase 2 antibody; Fructose 1 6 bisphosphatase isozyme 2 antibody; Fructose-1 antibody; Hexosediphosphatase antibody; MGC142192 antibody; Muscle FBPase antibody; Muscle fructose bisphosphatase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Rat
  • 免疫原：
    Recombinant Human Fructose-1,6-bisphosphatase isozyme 2 protein (283-339AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，FBP2 Antibody (CSB-PA008460LA01HU)，的標記方式是Non-conjugated。對于FBP2 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA008460LB01HU FBP2 Antibody, HRP conjugated ELISA
    FITC CSB-PA008460LC01HU FBP2 Antibody, FITC conjugated
    Biotin CSB-PA008460LD01HU FBP2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
  • 基因功能參考文獻：
    1. Results demonstrate that truncation of the evolutionarily conserved N-terminal residues of FBP2 results in a loss of its mitochondria-protective functions. PMID: 24412565
    2. FBP2 does negatively regulate cell growth, and reduced expression of FBP2 may contribute to carcinogenesis for gastric cancer. PMID: 24063558
    3. The key role in strong AMP binding to muscle isozyme play K20, T177 and Q179. PMID: 16213487
    4. The existence of highly AMP-sensitive muscle-like FBPase, activity of which is regulated by metabolite-dependent interaction with aldolase enables the precise regulation of muscle energy expenditures. PMID: 18214967
  • 亞細胞定位：
    Cell junction. Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line.
  • 蛋白家族：
    FBPase class 1 family
  • 組織特異性：
    Expressed in skeletal muscle (at protein level).
  • 數據庫鏈接：

    HGNC: 3607

    OMIM: 603027

    KEGG: hsa:8789

    STRING: 9606.ENSP00000364486

    UniGene: Hs.61255



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