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  4. FBP2 Antibody

FBP2 Antibody

  • 中文名稱：
    FBP2兔多克隆抗體
  • 貨號：
    CSB-PA103410
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA103410(FBP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA103410(FBP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    6-bisphosphatase isozyme 2 antibody; 6-bisphosphate 1-phosphohydrolase 2 antibody; D fructose 1 6 bisphosphate 1 phosphohydrolase 2 antibody; D-fructose-1 antibody; F16P2_HUMAN antibody; FBP 2 antibody; fbp2 antibody; FBPase 2 antibody; FBPase antibody; fructose 1 6 bisphosphatase 2 antibody; Fructose 1 6 bisphosphatase isozyme 2 antibody; Fructose-1 antibody; Hexosediphosphatase antibody; MGC142192 antibody; Muscle FBPase antibody; Muscle fructose bisphosphatase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human FBP2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
  • 基因功能參考文獻：
    1. Results demonstrate that truncation of the evolutionarily conserved N-terminal residues of FBP2 results in a loss of its mitochondria-protective functions. PMID: 24412565
    2. FBP2 does negatively regulate cell growth, and reduced expression of FBP2 may contribute to carcinogenesis for gastric cancer. PMID: 24063558
    3. The key role in strong AMP binding to muscle isozyme play K20, T177 and Q179. PMID: 16213487
    4. The existence of highly AMP-sensitive muscle-like FBPase, activity of which is regulated by metabolite-dependent interaction with aldolase enables the precise regulation of muscle energy expenditures. PMID: 18214967
  • 亞細胞定位：
    Cell junction. Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line.
  • 蛋白家族：
    FBPase class 1 family
  • 組織特異性：
    Expressed in skeletal muscle (at protein level).
  • 數據庫鏈接：

    HGNC: 3607

    OMIM: 603027

    KEGG: hsa:8789

    STRING: 9606.ENSP00000364486

    UniGene: Hs.61255



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