在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ERP44 Antibody

  • 中文名稱:
    ERP44兔多克隆抗體
  • 貨號:
    CSB-PA007801GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Endoplasmic reticulum resident protein 44 antibody; Endoplasmic reticulum resident protein 44 kDa antibody; Endoplasmic reticulum resident protein ERp44 antibody; ER protein 44 antibody; ERp44 antibody; ERP44_HUMAN antibody; KIAA0573 antibody; PDIA10 antibody; Protein disulfide isomerase family A; member 10 antibody; Thioredoxin domain containing 4 (endoplasmic reticulum) antibody; Thioredoxin domain containing protein 4 antibody; Thioredoxin domain-containing protein 4 antibody; UNQ532/PRO1075 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human ERP44
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum.
  • 基因功能參考文獻:
    1. Endogenous ERp44 is O-glycosylated and secreted by human primary endometrial cells, suggesting possible pathophysiological roles of these processes. PMID: 25097228
    2. findings indicated that overexpression of miR-101 could downregulate ERp44 PMID: 24804790
    3. the decrease in 5-HT uptake rates of GDM trophoblast is the consequence of defective insulin signaling, which entraps SERT with ERp44 and impairs its glycosylation. PMID: 25512553
    4. The ERp44 assembly control cycle couples secretion fidelity and efficiency downstream of the calnexin/calreticulin and BiP-dependent quality control cycles. PMID: 23685074
    5. ERp44 together with Ero1-Lalpha plays an important role in disulfide formation of SERT, which may be a prerequisite step for the assembly of SERT molecules in oligomeric form. PMID: 22451649
    6. contains a thioredoxin domain with a CRFS motif and is induced during ER stress PMID: 11847130
    7. Ero1alpha and Ero1beta are retained in the endoplasmic reticulum by interactions with PDI and ERp44 PMID: 16677073
    8. ERGIC-53 provides a platform that receives micro(2)L(2) subunits from the BiP-dependent checkpoint, assisting polymerization. In this process, ERp44 couples thiol-dependent assembly and quality control. PMID: 17805346
    9. ERp44-mediated retention of FGE, indicating that noncovalent interactions between ERp44 and FGE are sufficient to mediate ER retention. PMID: 18178549
    10. Study shows that SUMF1 interacts with protein disulfide isomerase (PDI) and ERp44, two thioredoxin family members residing in the early secretory pathway, and with ERGIC-53, a lectin that shuttles between the ER and the Golgi. PMID: 18508857
    11. Crystal structure of ERp44 at a resolution of 2.6 A, is presented. PMID: 18552768

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum lumen.
  • 數據庫鏈接:

    HGNC: 18311

    OMIM: 609170

    KEGG: hsa:23071

    STRING: 9606.ENSP00000262455

    UniGene: Hs.154023



主站蜘蛛池模板: 成人国产三级在线观看| 亚洲精品色午夜无码专区日韩| 国产尤物精品视频| 亚洲中文字幕永久在线全国| 2020久久天天躁狠狠躁夜夜| 337p日本欧洲亚洲大胆精品| 欧美日本国产va高清cabal| 久久亚洲精品无码网站| 2021国产精品香蕉在线观看| 大香伊人久久精品一区二区| 欧美丰满熟妇xx猛交| 黑人巨大跨种族video| 被c到高潮疯狂喷水国产| 麻豆国产av尤物网站尤物| 真人性囗交69视频| 国产色诱视频在线观看| 亚洲国产精品无码久久久蜜芽| 国产大片黄在线观看私人影院| 性裸交a片一区二区三区| 99尹人香蕉国产免费天天| 女人被狂躁高潮啊的视频在线看 | 老妇肥熟凸凹丰满刺激| 又湿又黄裸乳漫画无遮挡网站| 狠狠综合久久久久尤物| 人人妻人人玩人人澡人人爽| 激情毛片无码专区| 中文字幕精品视频在线看免费| 97久久草草超级碰碰碰| 亚洲熟女乱色综合亚洲图片| 成人国产网站v片免费观看| 狠狠色色综合站| 国产av无码国产av毛片| 午夜片神马影院福利| 亚洲va在线va天堂xxxx| 337p日本欧洲亚洲大胆在线| 学生妹亚洲一区二区| 国产精品综合一区二区三区| 国产午夜av秒播在线观看| 337p日本欧洲亚洲大胆| 一边捏奶头一边啪高潮视频| 综合 欧美 小说 另类 图|