在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ERP44 Antibody

ERP44 Antibody

  • 中文名稱：
    ERP44兔多克隆抗體
  • 貨號：
    CSB-PA580639
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA580639(ERP44 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE,Lysate: 40 μg,Lane 1-7: Raji cells, A549 cells, Hela cells, HepG2 cells, 231 cells, K562 cells, A431 cells,Primary antibody: CSB-PA580639(ERP44 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 10 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Endoplasmic reticulum resident protein 44 antibody; Endoplasmic reticulum resident protein 44 kDa antibody; Endoplasmic reticulum resident protein ERp44 antibody; ER protein 44 antibody; ERp44 antibody; ERP44_HUMAN antibody; KIAA0573 antibody; PDIA10 antibody; Protein disulfide isomerase family A; member 10 antibody; Thioredoxin domain containing 4 (endoplasmic reticulum) antibody; Thioredoxin domain containing protein 4 antibody; Thioredoxin domain-containing protein 4 antibody; UNQ532/PRO1075 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human ERP44
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum.
  • 基因功能參考文獻：
    1. Endogenous ERp44 is O-glycosylated and secreted by human primary endometrial cells, suggesting possible pathophysiological roles of these processes. PMID: 25097228
    2. findings indicated that overexpression of miR-101 could downregulate ERp44 PMID: 24804790
    3. the decrease in 5-HT uptake rates of GDM trophoblast is the consequence of defective insulin signaling, which entraps SERT with ERp44 and impairs its glycosylation. PMID: 25512553
    4. The ERp44 assembly control cycle couples secretion fidelity and efficiency downstream of the calnexin/calreticulin and BiP-dependent quality control cycles. PMID: 23685074
    5. ERp44 together with Ero1-Lalpha plays an important role in disulfide formation of SERT, which may be a prerequisite step for the assembly of SERT molecules in oligomeric form. PMID: 22451649
    6. contains a thioredoxin domain with a CRFS motif and is induced during ER stress PMID: 11847130
    7. Ero1alpha and Ero1beta are retained in the endoplasmic reticulum by interactions with PDI and ERp44 PMID: 16677073
    8. ERGIC-53 provides a platform that receives micro(2)L(2) subunits from the BiP-dependent checkpoint, assisting polymerization. In this process, ERp44 couples thiol-dependent assembly and quality control. PMID: 17805346
    9. ERp44-mediated retention of FGE, indicating that noncovalent interactions between ERp44 and FGE are sufficient to mediate ER retention. PMID: 18178549
    10. Study shows that SUMF1 interacts with protein disulfide isomerase (PDI) and ERp44, two thioredoxin family members residing in the early secretory pathway, and with ERGIC-53, a lectin that shuttles between the ER and the Golgi. PMID: 18508857
    11. Crystal structure of ERp44 at a resolution of 2.6 A, is presented. PMID: 18552768

    顯示更多

    收起更多

  • 亞細胞定位：
    Endoplasmic reticulum lumen.
  • 數據庫鏈接：

    HGNC: 18311

    OMIM: 609170

    KEGG: hsa:23071

    STRING: 9606.ENSP00000262455

    UniGene: Hs.154023



主站蜘蛛池模板： 中文字幕av伊人av无码av狼人 | 99久久精品费精品国产一区二区 | 久久国产精品2020免费| 欧美欧洲成本大片免费| 久久人人爽爽爽人久久久| 亚洲国产精品一区第二页| 真人做受试看120分钟小视频| 日本一区二区无卡高清视频| 亚洲老熟女与小伙bbwtv| 97精品国产手机| 米奇影视第四色| 98久久人妻少妇激情啪啪 | 亚洲国产香蕉碰碰人人| 一二区成人影院电影网| 国产精品你懂的在线播放| 免费永久看黄神器无码软件| 国产精品无码一区二区牛牛| 欧洲精品成人免费视频在线观看| 国产美女精品一区二区三区 | 国产一区二区三区小说| 狠狠色丁香婷婷综合潮喷| 青青青国产在线观看资源| 亚洲va中文在线播放| 国产狂喷潮在线观看中文| 欧美三级韩国三级日本三斤| 国产性猛交普通话对白| 中国农村妇女真实bbwbbwbbw | 欧美肥老太牲交| 国产婷婷综合在线视频| 大肉大捧一进一出好爽视色大师| 男人和女人高潮免费网站| 国产在线观看精品一区二区三区 | 强行交换配乱婬bd| 久久人妻xunleige无码| 精品久久久无码中文字幕天天| 日本丰满熟妇videos| 欧美丰腴丰满大屁股熟妇| 日韩免费无码人妻波多野| 天天天天做夜夜夜做| 18禁裸体女免费观看| 亚洲高清无码加勒比|