在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ERP44 Antibody

ERP44 Antibody

  • 中文名稱：
    ERP44兔多克隆抗體
  • 貨號：
    CSB-PA438768
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA438768(ERP44 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using CSB-PA438768(ERP44 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE,Lysate: 40 μg,Lane 1-7: A431 cells, K562 cells, 231 cells, HepG2 cells, Hela cells, A549 cells, Raji cells,Primary antibody: CSB-PA438768(ERP44 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 10 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Endoplasmic reticulum resident protein 44 antibody; Endoplasmic reticulum resident protein 44 kDa antibody; Endoplasmic reticulum resident protein ERp44 antibody; ER protein 44 antibody; ERp44 antibody; ERP44_HUMAN antibody; KIAA0573 antibody; PDIA10 antibody; Protein disulfide isomerase family A; member 10 antibody; Thioredoxin domain containing 4 (endoplasmic reticulum) antibody; Thioredoxin domain containing protein 4 antibody; Thioredoxin domain-containing protein 4 antibody; UNQ532/PRO1075 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human ERP44
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum.
  • 基因功能參考文獻：
    1. Endogenous ERp44 is O-glycosylated and secreted by human primary endometrial cells, suggesting possible pathophysiological roles of these processes. PMID: 25097228
    2. findings indicated that overexpression of miR-101 could downregulate ERp44 PMID: 24804790
    3. the decrease in 5-HT uptake rates of GDM trophoblast is the consequence of defective insulin signaling, which entraps SERT with ERp44 and impairs its glycosylation. PMID: 25512553
    4. The ERp44 assembly control cycle couples secretion fidelity and efficiency downstream of the calnexin/calreticulin and BiP-dependent quality control cycles. PMID: 23685074
    5. ERp44 together with Ero1-Lalpha plays an important role in disulfide formation of SERT, which may be a prerequisite step for the assembly of SERT molecules in oligomeric form. PMID: 22451649
    6. contains a thioredoxin domain with a CRFS motif and is induced during ER stress PMID: 11847130
    7. Ero1alpha and Ero1beta are retained in the endoplasmic reticulum by interactions with PDI and ERp44 PMID: 16677073
    8. ERGIC-53 provides a platform that receives micro(2)L(2) subunits from the BiP-dependent checkpoint, assisting polymerization. In this process, ERp44 couples thiol-dependent assembly and quality control. PMID: 17805346
    9. ERp44-mediated retention of FGE, indicating that noncovalent interactions between ERp44 and FGE are sufficient to mediate ER retention. PMID: 18178549
    10. Study shows that SUMF1 interacts with protein disulfide isomerase (PDI) and ERp44, two thioredoxin family members residing in the early secretory pathway, and with ERGIC-53, a lectin that shuttles between the ER and the Golgi. PMID: 18508857
    11. Crystal structure of ERp44 at a resolution of 2.6 A, is presented. PMID: 18552768

    顯示更多

    收起更多

  • 亞細胞定位：
    Endoplasmic reticulum lumen.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18311

    OMIM: 609170

    KEGG: hsa:23071

    STRING: 9606.ENSP00000262455

    UniGene: Hs.154023



主站蜘蛛池模板： 亚洲精品国产一区二区精华液| 国产激情电影综合在线看| 天堂а在线中文在线新版| 日韩成人无码中文字幕| 国产国拍精品av在线观看| 日产乱码一二三区别免费麻豆| 天天躁人人躁人人躁狂躁| 熟妇好大好深好满好爽| 无码免费午夜福利看片| 中文字幕日韩人妻不卡一区 | 丁香婷婷综合激情五月色| 无码人妻精品一区二区三区在线| 97国产精品人妻无码久久久| 在线人成免费视频69国产| 国产伦精品一区二区三区免.费| 又硬又粗又大一区二区三区视频| 男女又色又爽又爽视频| 777午夜福利理伦电影网| 久久精品国产精品国产精品污| 又紧又大又爽精品一区二区| 亚洲人成人伊人成综合网无码| 强行征服邻居人妻淑敏| 婷婷色婷婷开心五月四房播播| 在厨房拨开内裤进入在线视频| 国产成人国拍亚洲精品| 欧美真人性做爰一二区| 九九久久精品国产av片国产| 精品国产小视频在线观看| 亚洲欧洲日产国码无码网站| 无码国产精品一区二区免费模式| 99精品无码一区二区| 久久亚洲色www成人男男| 亚洲一卡二卡三卡四卡无卡麻豆| 色欲av永久无码精品无码蜜桃| 国产又黄又爽又色的免费| 国产v在线最新观看视频| 中国女人做爰视频| 久久97国产超碰青草| 人人爽人人添人人超| 日本乱偷人妻中文字幕在线| 色悠久久久久综合网香蕉|