在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. EPHA8 Antibody

EPHA8 Antibody

  • 中文名稱：
    EPHA8兔多克隆抗體
  • 貨號：
    CSB-PA007728GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    EPHA8
  • 別名：
    EPHA8 antibody; EEK antibody; HEK3 antibody; KIAA1459Ephrin type-A receptor 8 antibody; EC 2.7.10.1 antibody; EPH- and ELK-related kinase antibody; EPH-like kinase 3 antibody; EK3 antibody; hEK3 antibody; Tyrosine-protein kinase receptor EEK antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human EPHA8
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system plays also a role in axon guidance. Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth.
  • 基因功能參考文獻：
    1. Q-PCR and IHC staining revealed that EphA8 was highly expressed in OTSCC tissues, especially in advanced stage OTSCC tissues. Kaplan-Meier curve showed that high EphA8 expression was significantly associated with poor prognosis. PMID: 30300334
    2. High EPHA8 expression is associated with epithelial ovarian cancer. PMID: 26989075
    3. Human miR-10a and EphA8 regulate epithelial-mesenchymal transition (EMT) to affect glioma cell migration and invasion. PMID: 25683004
    4. RINL, as a GEF for Rab5 subfamily, is implicated in the EphA8-degradation pathway via its interaction with odin. PMID: 22291991
    5. role in stimulated cell migration in presnce of p110 gamma PI-3 kinase PMID: 12681484
    6. EphA8 receptor is capable of inducing a sustained increase in MAPK activity, thereby promoting neurite outgrowth in neuronal cells PMID: 15782114

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein. Cell projection. Early endosome membrane.
  • 蛋白家族：
    Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily
  • 數據庫鏈接：

    HGNC: 3391

    OMIM: 176945

    KEGG: hsa:2046

    STRING: 9606.ENSP00000166244

    UniGene: Hs.283613



主站蜘蛛池模板： 中文字幕aⅴ人妻一区二区| 天堂…中文在线最新版在线| 亚洲精品国产av成拍色拍婷婷| 人妻va精品va欧美va| 亚洲国产精品无码一线岛国 | 久久综合精品国产二区无码| 人妻内射一区二区在线视频| 久久国产美女精品久久| 99久久婷婷国产一区二区| 国产v亚洲v天堂无码| 久久一日本道色综合久久| 69天堂人成无码免费视频| 日韩欧美亚洲中文乱码| 手机在线看永久av片免费| 亚洲一区二区三区香蕉| 五月婷婷激情第四季| 亚洲中字慕日产2020| 久久亚洲精品无码va白人极品| 日本sm/羞辱/调教/捆绑视频 | 老熟女 露脸 嗷嗷叫| 国产成人无码免费视频97| 伊人久久精品无码麻豆一区| 色欲色香天天天综合网www| 鲁丝片一区二区三区毛片| 日本亚洲欧美在线视观看| 18禁免费吃奶摸下激烈视频| 午夜男女爽爽影院免费视频下载| 久久久无码精品午夜| 大胸美女污污污www网站| 久久精品无码专区免费| 99久久99久久精品国产片| 亚洲mv国产mv在线mv综合试看| 又粗又黄又爽视频免费看| 一 级 黄 色 片免费网站| 伊人久久精品在热线热| 92国产精品午夜福利无毒不卡| 国产午夜精品一区二区三区四区| 国产后入清纯学生妹| 国产成在线观看免费视频| 欧美天天综合色影久久精品| 丁香五月亚洲综合在线|